According to interviews, Sam Neill explained what made him decide to make the film was the scene in the screenplay in which the businessmen vampires buy morning coffee spiked with human blood.
In real life, Ethan Hawke had recently quit smoking cigarettes but his character, Dalton smokes several times throughout the film. Hawke therefore smoked soluble cigarettes during these scenes.
The makers of the movie hosted a contest in Worth1000.com (famous photo manipulation-contest site) to come up with images of how the world would look if nearly everyone were a vampire.
The scene in which Audrey orders Edward to drink some of her blood was not originally scripted and the idea was instead conceived during rehearsals by actors Claudia Karvan and Ethan Hawke.