- Diane is cousin to President John F. Kennedy's Press Secretary, the late Pierre Salinger.
- Appeared in three films with Paul Reubens: Pee-wee's Big Adventure (1985), Batman Returns (1992) and Pee-wee's Big Holiday (2016).
- She directed "Anna Karenina" for Oprah Winfrey and her Book of the Month Club.
- Tim Burton directed her in two of his films: Pee-wee's Big Adventure (1985) and Batman Returns (1992).
- There is one scene in Creature (1985) when Salinger's character (Melanie Bryce) is groped by Hans Rudy Hofner (played by Klaus Kinski). It was not in the script, but an invention of Kinski's.
- Was honored as President of the Jury and Mistress of Ceremonies of the 2007 Monaco International Film Festival.
- Was directed by two Academy Award winners: Clint Eastwood and Woody Allen.
- Friend of Paul Reubens.
- Provided acting lessons to actor Mikey Post for his role as Mike Green in Martin Scorsese's HBO series Mikey Post.
- Winner of the 2015 Independent Theater Award for her performance as an inebriated Tallulah Bankhead in Ensemble Theatre Company's production of Looped.
- Filmmaker Henry Jaglom cast her in five of his films: Venice/Venice (1992) (1992), Last Summer in the Hamptons (1995) (1995), Queen of the Lot (2010) (2010), Just 45 Minutes from Broadway (2012) (2012) and Ovation (2015) (2015).
- Received the LA Drama Critics Circle Award and Drama-Logue Award for her portrayal of a schizophrenic in Zephyr Theatre's production of Standing On My Knees.
- When Salinger had to leave the Edgemar Theatre's production of Henry Jaglom's Just 45 Minutes from Broadway (2012) to complete a project in she was previously committed, Jaglom asked Karen Black to step in the for actress--Black quickly agreed to play the part, but only for a few months.
- Off Broadway Theatre credits include, Phantasie (Vineyard Theatre), Agamemnon (I.R.T.) Stage Door (I.R.T.), A Midsummer Night's Dream (Riverside Church Theatre), and Desire Under the Elms (Mamaroneck Theatre).
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