Lori Loughlin in Curb Your Enthusiasm (2000)

Lori Loughlin and Jodie Sweetin in Full House (1987)

Victor Webster and Lori Loughlin in Homegrown Christmas (2018)

Lori Loughlin, Pascale Hutton, and Erin Krakow in When Calls the Heart (2014)

David Arquette, Jonathan Silverman, Kelly Hu, Greg Germann, Lori Loughlin, and Jackson Bond in In Case of Emergency (2007)

David Arquette and Lori Loughlin in In Case of Emergency (2007)

Lori Loughlin in In Case of Emergency (2007)

Kelly Hu and Lori Loughlin in In Case of Emergency (2007)

Greg Germann and Lori Loughlin in In Case of Emergency (2007)

Andrea Barber, Candace Cameron Bure, Dave Coulier, Lori Loughlin, and Jodie Sweetin in Fuller House (2016)

Lori Loughlin in When Calls the Heart (2014)

Lori Loughlin, Hrothgar Mathews, and Daniel Smith Arnold in When Calls the Heart (2014)

Lori Loughlin and Erin Krakow in When Calls the Heart (2014)

John Stamos, Candace Cameron Bure, Dave Coulier, Lori Loughlin, and Bob Saget in Fuller House (2016)

Ted Danson and Lori Loughlin in Curb Your Enthusiasm (2000)

Keanu Reeves and Lori Loughlin in The Night Before (1988)

Lori Loughlin and Shannon Presby in The New Kids (1985)

Kelly Preston, C. Thomas Howell, and Lori Loughlin in Secret Admirer (1985)

Jim Carrey, William McNamara, and Lori Loughlin in Doing Time on Maple Drive (1992)

James Spader and Lori Loughlin in The New Kids (1985)

Mary-Kate Olsen, John Stamos, Candace Cameron Bure, Dave Coulier, Lori Loughlin, Bob Saget, and Jodie Sweetin in Full House (1987)

Ashley Olsen, John Stamos, Candace Cameron Bure, Dave Coulier, Lori Loughlin, Bob Saget, and Jodie Sweetin in Full House (1987)

Ashley Olsen, Mary-Kate Olsen, John Stamos, Andrea Barber, Candace Cameron Bure, Dave Coulier, Lori Loughlin, Bob Saget, Jodie Sweetin, Blake Tuomy-Wilhoit, Dylan Tuomy-Wilhoit, and Scott Weinger in Full House (1987)