- Son of Dom DeLuise and Carol Arthur.
- Godmother was Anne Bancroft.
- Father, with ex-wife Brigitte DeLuise, of daughters Riley DeLuise (Riley DeStefano DeLuise; b. August 4, 1993) and Dylan DeLuise (b. 1998).
- David, brother Michael DeLuise, brother Peter DeLuise, and father Dom DeLuise have all appeared as guests on Stargate SG-1 (1997). Brother Peter is a regular director and creative consultant for the series.
- His daughter, Riley DeLuise, appeared in Too Smooth (1998) alongside of him.
- In Happy (1983), he appeared with his father Dom DeLuise, his mother Carol Arthur and his two brothers, Michael DeLuise and Peter DeLuise.
- Has guest starred in all three incarnations of the CSI franchise, playing different characters in all three shows.
- Younger brother of Peter DeLuise and Michael DeLuise.
- Father of actress Riley DeLuise.
- Brother-in-law of actress Anne Marie DeLuise.
- His paternal grandparents were Italian. His mother is of half Italian and half German descent.
- He and brother Michael DeLuise both appeared in episodes of CSI: NY (2004). They also appeared in two episodes of Gilmore Girls (2000) in which they played brothers.
- David, Michael, Peter, and Dom DeLuise all appeared on 21 Jump Street with David's character being the only one not related to the other's.
- (October 17, 2019) Married his girlfriend of 4 years Julia Stoepel.
- Ex-brother-in-law of Gina Nemo.
Contribute to this page
Suggest an edit or add missing content