- When asked for his autograph later in life, Vincent Price would often sign her name. When asked why, Price would say that he promised her on her deathbed he would do his best to keep her name alive.
- Friends with Marlene Dietrich, who considered Dolores "the most beautiful woman in Hollywood".
- She contributed money to a statue likeness of her as the title character in Evangeline (1929). Upon completion in 1930, the statue was placed beside St. Martin de Tours Catholic Church in St. Martinville, Louisiana. The statue rests on a spot marking the alleged burial place of Emmeline Labiche, who local lore claims was the inspiration behind Longfellow's tragic heroine. It has become a popular tourist attraction and is known as "The Evangeline Statue".
- Reportedly slept for 16 hours a day to maintain her beauty.
- In February 1934, it was announced in the press that Dolores Del Rio was tired of playing native girl roles and has bobbed her hair, had a permanent and put on swanky clothes for her upcoming RKO Radio Picture Dance of Desire. The movie eventually never was made.
- She won the Ariel Award (Mexican Academy Award) three times: in 1946 for Las abandonadas (1945); in 1952 for Doña Perfecta (1951) and in 1954 for El niño y la niebla (1953).
- On August 19, 2020, she was honored with a day of her filmography during the Turner Classic Movies Summer Under the Stars.
- Often considered the female Rudolph Valentino, "the female Latin Lover".
- Member of the jury at the Berlin International Film Festival in 1962
- She was awarded a Star on the Hollywood Walk of Fame at 1630 Vine Street in Hollywood, California on February 8, 1960.
- Wampas Baby Star of 1926.
- She was very proud of her Spanish and Native Mexican roots. Through her father's family, the Asúnsolos, she was of Spanish Basque descent. Through her mother's family, the López-Negretes, she was mixed-race and had both Spanish and Toltec ancestors. The Toltecs were a Mesoamerican civilization that lived in what is now the State of Hidalgo, Mexico.
- Along with legendary actresses Sara García and Andrea Palma, she became one of the first leading ladies of Mexican cinema.
- Grand-aunt of actor Adam Del Rio.
- Member of the jury at the Cannes Film Festival in 1957
- Second actress, after María Félix, to win three Ariel Awards for Best Actress (1946, 1952, 1954). She also received nominations on two other occasions (1947, 1951), making her a five-time nominee. In 1975, she won a Special Ariel Award for her career.
- Following her death, she was cremated and interred at Panteon Civil de Delores in Mexico City, Mexico, specifically on the Rotunda of Illustrious Persons. She passed away on April 11, 1983, four months away from what would have been her 79th birthday on August 3.
- Between her second and third marriages, she was briefly engaged to Orson Welles.
- At the time of her death, she was planning her return to the Mexican stage in a production of the play "A Lion in Winter" ("Un león en invierno").
- In the early 1940s, when her Hollywood career began to decline, Del Río returned to Mexico and joined the Mexican film industry, which at that time was at its peak.
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