This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

Drugs targeting amyloid plaques have failed to show efficacy in clinical trials. A new approach is needed to tackle AD ...

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.

Nevertheless, we will analyze different chromatin data (DNA methylation and different histone post-translational modifications) from previously published works in 2i/LIF and Serum/LIF and compare them ...

What is multi-omics? Multi-omics is the integration of multiple omic data during analysis. Omic data principally includes ...

These modifications increase chromatin accessibility, influencing growth, differentiation, and ion transport, with contrasting effects on normal and colorectal cancer cells. Study: Short-chain ...

Dunn, recently carried out a study exploring how DNA methylation, an epigenetic modification that entails the addition of a methyl group to the DNA, contributes to the well-documented relationship ...

Late-onset Alzheimer's disease is a debilitating, progressive neurodegenerative disease that affects about 7 million ...

The well-known mechanism by which DNA methylation contributes to cancer is through the focal hypermethylation of promoters of tumor-suppressor genes. In general, DNA hypermethylation occurs at CpG ...

In summary, modern techniques for DNA methylation permit sensitive and quantitative detection of hypermethylated tumor-suppressor genes in all biological fluids and biopsy specimens. Accordingly ...