Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment U Koch, E Fiorini, R Benedito, V Besseyrias, K Schuster-Gossler, ... The Journal of experimental medicine 205 (11), 2515-2523, 2008 | 559 | 2008 |
The role of Hoxa-3 in mouse thymus and thyroid development NR Manley, MR Capecchi Development 121 (7), 1989-2003, 1995 | 511 | 1995 |
Loss of Hox-A1 (Hox-1.6) function results in the reorganization of the murine hindbrain EM Carpenter, JM Goddard, O Chisaka, NR Manley, MR Capecchi Development 118 (4), 1063-1075, 1993 | 413 | 1993 |
Mechanisms of thymus organogenesis and morphogenesis J Gordon, NR Manley Development 138 (18), 3865-3878, 2011 | 381 | 2011 |
Developing a new paradigm for thymus organogenesis CC Blackburn, NR Manley Nature Reviews Immunology 4 (4), 278-289, 2004 | 369 | 2004 |
An evolutionary perspective on the mechanisms of immunosenescence DP Shanley, D Aw, NR Manley, DB Palmer Trends in immunology 30 (7), 374-381, 2009 | 353 | 2009 |
HoxGroup 3 Paralogs Regulate the Development and Migration of the Thymus, Thyroid, and Parathyroid Glands NR Manley, MR Capecchi Developmental biology 195 (1), 1-15, 1998 | 346 | 1998 |
Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve JM Goddard, M Rossel, NR Manley, MR Capecchi Development 122 (10), 3217-3228, 1996 | 329 | 1996 |
Changes in primary lymphoid organs with aging IK Chinn, CC Blackburn, NR Manley, GD Sempowski Seminars in immunology 24 (5), 309-320, 2012 | 318 | 2012 |
Gcm2 and Foxn1 mark early parathyroid-and thymus-specific domains in the developing third pharyngeal pouch J Gordon, AR Bennett, CC Blackburn, NR Manley Mechanisms of development 103 (1-2), 141-143, 2001 | 306 | 2001 |
γ-Secretase inhibitors repress thymocyte development BK Hadland, NR Manley, D Su, GD Longmore, CL Moore, MS Wolfe, ... Proceedings of the National Academy of Sciences 98 (13), 7487-7491, 2001 | 269 | 2001 |
Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner L Chen, S Xiao, NR Manley Blood, The Journal of the American Society of Hematology 113 (3), 567-574, 2009 | 264 | 2009 |
Functional evidence for a single endodermal origin for the thymic epithelium J Gordon, VA Wilson, NF Blair, J Sheridan, A Farley, L Wilson, NR Manley, ... Nature immunology 5 (5), 546-553, 2004 | 262 | 2004 |
An ancient gene network is co-opted for teeth on old and new jaws GJ Fraser, CD Hulsey, RF Bloomquist, K Uyesugi, NR Manley, ... PLoS biology 7 (2), e1000031, 2009 | 254 | 2009 |
Coordination between CCR7-and CCR9-mediated chemokine signals in prevascular fetal thymus colonization C Liu, F Saito, Z Liu, Y Lei, S Uehara, P Love, M Lipp, S Kondo, N Manley, ... Blood 108 (8), 2531-2539, 2006 | 252 | 2006 |
Thymus organogenesis and molecular mechanisms of thymic epithelial cell differentiation NR Manley Seminars in immunology 12 (5), 421-428, 2000 | 226 | 2000 |
A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation D Su, S Navarre, W Oh, BG Condie, NR Manley Nature immunology 4 (11), 1128-1135, 2003 | 204 | 2003 |
An organized and functional thymus generated from FOXN1-reprogrammed fibroblasts N Bredenkamp, S Ulyanchenko, KE O’Neill, NR Manley, HJ Vaidya, ... Nature cell biology 16 (9), 902-908, 2014 | 195 | 2014 |
Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures NR Manley, MR Capecchi Developmental biology 192 (2), 274-288, 1997 | 192 | 1997 |
Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis D Su, S Ellis, A Napier, K Lee, NR Manley Developmental biology 236 (2), 316-329, 2001 | 191 | 2001 |