Supplementary Data 2.  Differential gene expression analysis results.,,,,,,,,,
Probe.Set.ID,Gene.Symbol,Entrez.Gene,Ensembl,Gene.Title,Gene.Ontology.Biological.Process,Gene.Ontology.Cellular.Component,logFC,P.Value,FDR
204558_at,RAD54L,8438,---,RAD54-like (S. cerevisiae),0000724 // double-strand break repair via homologous recombination // inferred from electronic annotation /// 0000733 // DNA strand renaturation // inferred from direct assay /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // inferred from electronic annotation /// 0006310 // DNA recombination // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007126 // meiotic nuclear division // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation,0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay,-0.221173793,3.75E-05,TRUE
208910_s_at,C1QBP,708,ENSG00000108561 /// OTTHUMG00000177875,"complement component 1, q subcomponent binding protein","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0002376 // immune system process // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0006958 // complement activation, classical pathway // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0007597 // blood coagulation, intrinsic pathway // traceable author statement /// 0008380 // RNA splicing // inferred from electronic annotation /// 0014065 // phosphatidylinositol 3-kinase signaling // inferred from mutant phenotype /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0030449 // regulation of complement activation // inferred from direct assay /// 0032689 // negative regulation of interferon-gamma production // inferred from direct assay /// 0032695 // negative regulation of interleukin-12 production // inferred from direct assay /// 0039534 // negative regulation of MDA-5 signaling pathway // inferred from direct assay /// 0039536 // negative regulation of RIG-I signaling pathway // inferred from direct assay /// 0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042256 // mature ribosome assembly // inferred from mutant phenotype /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045087 // innate immune response // inferred from electronic annotation /// 0045785 // positive regulation of cell adhesion // inferred from mutant phenotype /// 0048025 // negative regulation of mRNA splicing, via spliceosome // inferred from direct assay /// 0050687 // negative regulation of defense response to virus // inferred from mutant phenotype /// 0051897 // positive regulation of protein kinase B signaling // inferred from mutant phenotype /// 0070131 // positive regulation of mitochondrial translation // inferred from sequence or structural similarity /// 0090023 // positive regulation of neutrophil chemotaxis // inferred from direct assay /// 1900026 // positive regulation of substrate adhesion-dependent cell spreading // inferred from mutant phenotype /// 1901165 // positive regulation of trophoblast cell migration // inferred from mutant phenotype /// 2000510 // positive regulation of dendritic cell chemotaxis // inferred from mutant phenotype",0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay,-0.244146879,6.26E-05,TRUE
203418_at,CCNA2,890,ENSG00000145386 /// OTTHUMG00000133072,cyclin A2,"0000079 // regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from electronic annotation /// 0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007095 // mitotic G2 DNA damage checkpoint // traceable author statement /// 0007265 // Ras protein signal transduction // inferred from expression pattern /// 0010389 // regulation of G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0031100 // organ regeneration // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0033762 // response to glucagon // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0048146 // positive regulation of fibroblast proliferation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation",0001939 // female pronucleus // inferred from electronic annotation /// 0001940 // male pronucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay,-0.39202444,9.99E-05,TRUE
205393_s_at,CHEK1,1111,ENSG00000149554 /// OTTHUMG00000165853,checkpoint kinase 1,0000077 // DNA damage checkpoint // inferred from direct assay /// 0000077 // DNA damage checkpoint // inferred from mutant phenotype /// 0000086 // G2/M transition of mitotic cell cycle // inferred from electronic annotation /// 0006260 // DNA replication // traceable author statement /// 0006281 // DNA repair // inferred from mutant phenotype /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0006975 // DNA damage induced protein phosphorylation // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0010468 // regulation of gene expression // inferred from electronic annotation /// 0010569 // regulation of double-strand break repair via homologous recombination // inferred from direct assay /// 0010767 // regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018107 // peptidyl-threonine phosphorylation // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0035407 // histone H3-T11 phosphorylation // inferred from direct assay /// 0035407 // histone H3-T11 phosphorylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0045839 // negative regulation of mitosis // inferred from direct assay /// 0046602 // regulation of mitotic centrosome separation // inferred from direct assay /// 0048096 // chromatin-mediated maintenance of transcription // inferred from sequence or structural similarity /// 0071260 // cellular response to mechanical stimulus // inferred from expression pattern /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071313 // cellular response to caffeine // inferred from electronic annotation /// 0090399 // replicative senescence // non-traceable author statement /// 2000615 // regulation of histone H3-K9 acetylation // inferred from sequence or structural similarity,"0000781 // chromosome, telomeric region // inferred from direct assay /// 0000785 // chromatin // inferred from sequence or structural similarity /// 0000794 // condensed nuclear chromosome // inferred from direct assay /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005657 // replication fork // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay",-0.277678851,0.000128709,TRUE
220196_at,MUC16,94025,ENSG00000181143 /// OTTHUMG00000169191,"mucin 16, cell surface associated",0007155 // cell adhesion // non-traceable author statement /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement,0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0019898 // extrinsic component of membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.53548541,0.000134324,TRUE
211851_x_at,BRCA1,672,ENSG00000012048 /// OTTHUMG00000157426,"breast cancer 1, early onset","0000724 // double-strand break repair via homologous recombination // inferred from direct assay /// 0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006301 // postreplication repair // inferred from direct assay /// 0006302 // double-strand break repair // inferred from mutant phenotype /// 0006302 // double-strand break repair // traceable author statement /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006349 // regulation of gene expression by genetic imprinting // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006359 // regulation of transcription from RNA polymerase III promoter // traceable author statement /// 0006629 // lipid metabolic process // inferred from electronic annotation /// 0006631 // fatty acid metabolic process // inferred from electronic annotation /// 0006633 // fatty acid biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // traceable author statement /// 0006978 // DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007098 // centrosome cycle // inferred from electronic annotation /// 0008630 // intrinsic apoptotic signaling pathway in response to DNA damage // inferred from direct assay /// 0009048 // dosage compensation by inactivation of X chromosome // inferred from electronic annotation /// 0010212 // response to ionizing radiation // inferred from mutant phenotype /// 0016567 // protein ubiquitination // inferred from direct assay /// 0030521 // androgen receptor signaling pathway // non-traceable author statement /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay /// 0031572 // G2 DNA damage checkpoint // inferred from mutant phenotype /// 0034446 // substrate adhesion-dependent cell spreading // inferred from direct assay /// 0035066 // positive regulation of histone acetylation // inferred from direct assay /// 0035067 // negative regulation of histone acetylation // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // traceable author statement /// 0042981 // regulation of apoptotic process // traceable author statement /// 0043009 // chordate embryonic development // inferred from electronic annotation /// 0043627 // response to estrogen // inferred from direct assay /// 0044030 // regulation of DNA methylation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from mutant phenotype /// 0045739 // positive regulation of DNA repair // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0046600 // negative regulation of centriole replication // non-traceable author statement /// 0051571 // positive regulation of histone H3-K4 methylation // inferred from direct assay /// 0051572 // negative regulation of histone H3-K4 methylation // inferred from electronic annotation /// 0051573 // negative regulation of histone H3-K9 methylation // inferred from direct assay /// 0051574 // positive regulation of histone H3-K9 methylation // inferred from electronic annotation /// 0051865 // protein autoubiquitination // inferred from direct assay /// 0070512 // positive regulation of histone H4-K20 methylation // inferred from direct assay /// 0071158 // positive regulation of cell cycle arrest // inferred from direct assay /// 0071681 // cellular response to indole-3-methanol // inferred from direct assay /// 0085020 // protein K6-linked ubiquitination // inferred from direct assay /// 2000145 // regulation of cell motility // inferred from direct assay /// 2000617 // positive regulation of histone H3-K9 acetylation // inferred from direct assay /// 2000620 // positive regulation of histone H4-K16 acetylation // inferred from direct assay",0000151 // ubiquitin ligase complex // non-traceable author statement /// 0000793 // condensed chromosome // inferred from electronic annotation /// 0000794 // condensed nuclear chromosome // inferred from electronic annotation /// 0001726 // ruffle // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay /// 0008274 // gamma-tubulin ring complex // non-traceable author statement /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0031436 // BRCA1-BARD1 complex // inferred from direct assay /// 0031941 // filamentous actin // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0070531 // BRCA1-A complex // inferred from direct assay,-0.093505204,0.000146928,TRUE
221521_s_at,GINS2,51659,ENSG00000131153 /// OTTHUMG00000137646,GINS complex subunit 2 (Psf2 homolog),0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement,0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement,-0.316675609,0.000147192,TRUE
219311_at,CEP76,79959,ENSG00000101624 /// OTTHUMG00000131701,centrosomal protein 76kDa,0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0046599 // regulation of centriole replication // inferred from mutant phenotype,0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0043234 // protein complex // inferred from direct assay,-0.253578927,0.000192692,TRUE
210170_at,PDLIM3,27295,ENSG00000154553 /// OTTHUMG00000160412,PDZ and LIM domain 3,0007015 // actin filament organization // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation,0005737 // cytoplasm // inferred from direct assay /// 0015629 // actin cytoskeleton // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation,0.130754468,0.000201162,TRUE
203564_at,FANCG,2189,ENSG00000221829 /// OTTHUMG00000019850,"Fanconi anemia, complementation group G",0000075 // cell cycle checkpoint // traceable author statement /// 0000160 // phosphorelay signal transduction system // inferred from electronic annotation /// 0001541 // ovarian follicle development // inferred from electronic annotation /// 0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007005 // mitochondrion organization // inferred from mutant phenotype /// 0007286 // spermatid development // inferred from electronic annotation /// 0009314 // response to radiation // inferred from electronic annotation,0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0043240 // Fanconi anaemia nuclear complex // inferred from direct assay,-0.23575947,0.000219338,TRUE
209839_at,DNM3,26052,ENSG00000197959 /// OTTHUMG00000034913,dynamin 3,0006184 // GTP catabolic process // inferred from electronic annotation /// 0006184 // GTP catabolic process // inferred from sequence or structural similarity /// 0006897 // endocytosis // inferred from sequence or structural similarity /// 0007416 // synapse assembly // inferred from sequence or structural similarity /// 0008152 // metabolic process // inferred from electronic annotation /// 0046847 // filopodium assembly // inferred from sequence or structural similarity,0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0014069 // postsynaptic density // inferred from sequence or structural similarity /// 0043197 // dendritic spine // inferred from sequence or structural similarity /// 0048471 // perinuclear region of cytoplasm // inferred from sequence or structural similarity,0.170009575,0.00024109,TRUE
209286_at,CDC42EP3,10602,ENSG00000163171 /// OTTHUMG00000100971,CDC42 effector protein (Rho GTPase binding) 3,0007165 // signal transduction // traceable author statement /// 0008360 // regulation of cell shape // inferred from electronic annotation,0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation,0.281415126,0.00029205,TRUE
219787_s_at,ECT2,1894,ENSG00000114346 /// OTTHUMG00000156762,epithelial cell transforming 2,0000902 // cell morphogenesis // inferred from electronic annotation /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032147 // activation of protein kinase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from direct assay /// 0032321 // positive regulation of Rho GTPase activity // inferred from mutant phenotype /// 0032467 // positive regulation of cytokinesis // inferred from direct assay /// 0032467 // positive regulation of cytokinesis // inferred from mutant phenotype /// 0032862 // activation of Rho GTPase activity // inferred from direct assay /// 0032863 // activation of Rac GTPase activity // inferred from mutant phenotype /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0042307 // positive regulation of protein import into nucleus // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043089 // positive regulation of Cdc42 GTPase activity // inferred from direct assay /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from mutant phenotype /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051260 // protein homooligomerization // inferred from direct assay /// 0051301 // cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0070830 // tight junction assembly // inferred from mutant phenotype /// 0071277 // cellular response to calcium ion // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay /// 0097190 // apoptotic signaling pathway // traceable author statement,0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005911 // cell-cell junction // inferred from direct assay /// 0005923 // tight junction // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032154 // cleavage furrow // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay /// 0097149 // centralspindlin complex // inferred from direct assay,-0.282485489,0.000298677,TRUE
45633_at,GINS3,64785,ENSG00000181938 /// OTTHUMG00000133486,GINS complex subunit 3 (Psf3 homolog),0006260 // DNA replication // inferred from electronic annotation,0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay,-0.15535215,0.000313337,TRUE
212656_at,TSFM,10102,ENSG00000123297 /// OTTHUMG00000153042,"Ts translation elongation factor, mitochondrial","0006412 // translation // inferred from electronic annotation /// 0006414 // translational elongation // inferred from electronic annotation /// 0032784 // regulation of DNA-templated transcription, elongation // traceable author statement",0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay,-0.165239017,0.000343164,TRUE
203362_s_at,MAD2L1,4085,ENSG00000164109 /// OTTHUMG00000132967,MAD2 mitotic arrest deficient-like 1 (yeast),0000070 // mitotic sister chromatid segregation // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // inferred from direct assay /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0045930 // negative regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0060564 // negative regulation of mitotic anaphase-promoting complex activity // inferred from direct assay /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype,"0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay",-0.314168065,0.000357107,TRUE
215136_s_at,EXOSC8,11340,ENSG00000120699 /// OTTHUMG00000016742,exosome component 8,"0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // traceable author statement /// 0006364 // rRNA processing // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0043928 // exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay // traceable author statement",0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement,-0.206912468,0.000359263,TRUE
208732_at,RAB2A,5862,ENSG00000104388 /// OTTHUMG00000134298,"RAB2A, member RAS oncogene family",0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from direct assay /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006886 // intracellular protein transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006913 // nucleocytoplasmic transport // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation,0000139 // Golgi membrane // traceable author statement /// 0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0033116 // endoplasmic reticulum-Golgi intermediate compartment membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.180746313,0.000437038,TRUE
216962_at,RPAIN,84268,ENSG00000129197 /// OTTHUMG00000177872,RPA interacting protein,0006261 // DNA-dependent DNA replication // inferred from physical interaction /// 0006281 // DNA repair // inferred from physical interaction /// 0006310 // DNA recombination // inferred from physical interaction /// 0006606 // protein import into nucleus // inferred from direct assay /// 0009411 // response to UV // inferred from direct assay,0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016605 // PML body // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation,-0.121897891,0.000452879,TRUE
202483_s_at,RANBP1,5902,ENSG00000099901 /// OTTHUMG00000150490,RAN binding protein 1,0007051 // spindle organization // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0016032 // viral process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0046604 // positive regulation of mitotic centrosome separation // inferred from electronic annotation /// 0046907 // intracellular transport // inferred from electronic annotation /// 0050790 // regulation of catalytic activity // traceable author statement,0005634 // nucleus // traceable author statement /// 0005635 // nuclear envelope // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005813 // centrosome // inferred from electronic annotation,-0.201488256,0.000516782,TRUE
218447_at,CMC2,56942,ENSG00000103121 /// OTTHUMG00000137625,C-x(9)-C motif containing 2,---,0005739 // mitochondrion // inferred from direct assay,-0.173942794,0.000517388,TRUE
201708_s_at,NIPSNAP1,8508,ENSG00000184117 /// OTTHUMG00000151294,nipsnap homolog 1 (C. elegans),0019233 // sensory perception of pain // inferred from electronic annotation,0005739 // mitochondrion // inferred from sequence or structural similarity /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0097060 // synaptic membrane // inferred from electronic annotation,-0.230017181,0.000553804,TRUE
209090_s_at,SH3GLB1,51100,ENSG00000097033 /// OTTHUMG00000010257,SH3-domain GRB2-like endophilin B1,0006654 // phosphatidic acid biosynthetic process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008654 // phospholipid biosynthetic process // inferred from electronic annotation /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0051084 // 'de novo' posttranslational protein folding // inferred from electronic annotation /// 0051259 // protein oligomerization // inferred from direct assay /// 1900740 // positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway // inferred from electronic annotation,0000139 // Golgi membrane // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005741 // mitochondrial outer membrane // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043234 // protein complex // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.213152039,0.000557638,TRUE
220651_s_at,MCM10,55388,ENSG00000065328 /// OTTHUMG00000017694,minichromosome maintenance complex component 10,0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0008283 // cell proliferation // inferred from electronic annotation,0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay,-0.297073956,0.000561397,TRUE
208085_s_at,ARHGAP6,395,ENSG00000047648 /// OTTHUMG00000021134,Rho GTPase activating protein 6,0007015 // actin filament organization // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007202 // activation of phospholipase C activity // inferred from direct assay /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // non-traceable author statement /// 0009967 // positive regulation of signal transduction // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from direct assay /// 0030041 // actin filament polymerization // non-traceable author statement /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0043087 // regulation of GTPase activity // inferred from sequence or structural similarity /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048041 // focal adhesion assembly // inferred from electronic annotation /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051497 // negative regulation of stress fiber assembly // inferred from mutant phenotype /// 0051895 // negative regulation of focal adhesion assembly // inferred from mutant phenotype,0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from mutant phenotype /// 0005829 // cytosol // traceable author statement /// 0005884 // actin filament // non-traceable author statement /// 0015629 // actin cytoskeleton // inferred from sequence or structural similarity,0.052016037,0.000575119,TRUE
212086_x_at,LMNA,4000,ENSG00000160789 /// OTTHUMG00000013961,lamin A/C,0000278 // mitotic cell cycle // traceable author statement /// 0006915 // apoptotic process // traceable author statement /// 0006921 // cellular component disassembly involved in execution phase of apoptosis // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0006997 // nucleus organization // inferred from electronic annotation /// 0006998 // nuclear envelope organization // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0007084 // mitotic nuclear envelope reassembly // traceable author statement /// 0007517 // muscle organ development // inferred from mutant phenotype /// 0008219 // cell death // inferred from electronic annotation /// 0030334 // regulation of cell migration // inferred from sequence or structural similarity /// 0030951 // establishment or maintenance of microtubule cytoskeleton polarity // inferred from sequence or structural similarity /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0034504 // protein localization to nucleus // inferred from sequence or structural similarity /// 0035105 // sterol regulatory element binding protein import into nucleus // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0044267 // cellular protein metabolic process // traceable author statement /// 0055015 // ventricular cardiac muscle cell development // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from expression pattern /// 0090201 // negative regulation of release of cytochrome c from mitochondria // inferred from electronic annotation /// 0090343 // positive regulation of cell aging // inferred from direct assay /// 2001237 // negative regulation of extrinsic apoptotic signaling pathway // inferred from electronic annotation,0005634 // nucleus // inferred from direct assay /// 0005635 // nuclear envelope // inferred from direct assay /// 0005635 // nuclear envelope // traceable author statement /// 0005638 // lamin filament // inferred from electronic annotation /// 0005638 // lamin filament // traceable author statement /// 0005652 // nuclear lamina // traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005882 // intermediate filament // traceable author statement /// 0016607 // nuclear speck // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay,0.160263201,0.000640653,TRUE
200788_s_at,PEA15,8682,ENSG00000162734 /// OTTHUMG00000031605,phosphoprotein enriched in astrocytes 15,0006810 // transport // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0008643 // carbohydrate transport // inferred from electronic annotation /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0046325 // negative regulation of glucose import // inferred from direct assay /// 1902042 // negative regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from direct assay /// 1902043 // positive regulation of extrinsic apoptotic signaling pathway via death domain receptors // inferred from electronic annotation,0005737 // cytoplasm // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement,0.160600417,0.000645693,TRUE
201531_at,ZFP36,7538,ENSG00000128016 /// OTTHUMG00000182970,ZFP36 ring finger protein,"0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0000288 // nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from direct assay /// 0000289 // nuclear-transcribed mRNA poly(A) tail shortening // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006402 // mRNA catabolic process // inferred from direct assay /// 0010467 // gene expression // traceable author statement /// 0016070 // RNA metabolic process // traceable author statement /// 0016071 // mRNA metabolic process // traceable author statement /// 0032680 // regulation of tumor necrosis factor production // inferred from direct assay /// 0035278 // negative regulation of translation involved in gene silencing by miRNA // inferred from sequence or structural similarity /// 0042594 // response to starvation // inferred from direct assay /// 0043488 // regulation of mRNA stability // inferred from electronic annotation /// 0045638 // negative regulation of myeloid cell differentiation // inferred from electronic annotation /// 0050728 // negative regulation of inflammatory response // inferred from electronic annotation /// 0050779 // RNA destabilization // inferred from electronic annotation /// 0060213 // positive regulation of nuclear-transcribed mRNA poly(A) tail shortening // inferred from direct assay /// 0070935 // 3'-UTR-mediated mRNA stabilization // inferred from direct assay /// 1900153 // positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay // inferred from sequence or structural similarity",0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0010494 // cytoplasmic stress granule // inferred from direct assay,0.346904477,0.00067465,TRUE
203871_at,SENP3,26168,ENSG00000161956 /// OTTHUMG00000178333,SUMO1/sentrin/SMT3 specific peptidase 3,0006508 // proteolysis // inferred from electronic annotation /// 0019538 // protein metabolic process // inferred from electronic annotation,0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0071339 // MLL1 complex // inferred from direct assay,-0.15490449,0.000699386,TRUE
217806_s_at,POLDIP2,26073,ENSG00000004142 /// OTTHUMG00000132065,"polymerase (DNA-directed), delta interacting protein 2",0070584 // mitochondrion morphogenesis // inferred from electronic annotation,0005634 // nucleus // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay,-0.126199591,0.000718271,TRUE
209053_s_at,WHSC1,7468,ENSG00000109685 /// OTTHUMG00000121147,Wolf-Hirschhorn syndrome candidate 1,"0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0003149 // membranous septum morphogenesis // inferred from electronic annotation /// 0003289 // atrial septum primum morphogenesis // inferred from electronic annotation /// 0003290 // atrial septum secundum morphogenesis // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0016568 // chromatin modification // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0060348 // bone development // inferred from electronic annotation",0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay,-0.270730162,0.000743746,TRUE
212870_at,SOS2,6655,ENSG00000100485 /// OTTHUMG00000140292,son of sevenless homolog 2 (Drosophila),0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007411 // axon guidance // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0051057 // positive regulation of small GTPase mediated signal transduction // inferred from electronic annotation /// 0097190 // apoptotic signaling pathway // traceable author statement,0005622 // intracellular // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement,0.176456823,0.000768475,TRUE
201693_s_at,EGR1,1958,ENSG00000120738 /// OTTHUMG00000129197,early growth response 1,"0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0001975 // response to amphetamine // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from direct assay /// 0007611 // learning or memory // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009749 // response to glucose // inferred from electronic annotation /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030217 // T cell differentiation // inferred from electronic annotation /// 0030509 // BMP signaling pathway // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032354 // response to follicle-stimulating hormone // inferred from electronic annotation /// 0032868 // response to insulin // inferred from electronic annotation /// 0032869 // cellular response to insulin stimulus // inferred from electronic annotation /// 0033233 // regulation of protein sumoylation // inferred from direct assay /// 0034465 // response to carbon monoxide // inferred from electronic annotation /// 0034698 // response to gonadotropin // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0035914 // skeletal muscle cell differentiation // not recorded /// 0042220 // response to cocaine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // not recorded /// 0043525 // positive regulation of neuron apoptotic process // inferred from electronic annotation /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048169 // regulation of long-term neuronal synaptic plasticity // not recorded /// 0048709 // oligodendrocyte differentiation // inferred from electronic annotation /// 0051602 // response to electrical stimulus // inferred from electronic annotation /// 0060291 // long-term synaptic potentiation // inferred from electronic annotation /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0071236 // cellular response to antibiotic // inferred from electronic annotation /// 0071260 // cellular response to mechanical stimulus // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071317 // cellular response to isoquinoline alkaloid // inferred from electronic annotation /// 0071320 // cellular response to cAMP // not recorded /// 0071363 // cellular response to growth factor stimulus // inferred from electronic annotation /// 0071371 // cellular response to gonadotropin stimulus // not recorded /// 0071372 // cellular response to follicle-stimulating hormone stimulus // inferred from electronic annotation /// 0071383 // cellular response to steroid hormone stimulus // inferred from electronic annotation /// 0071455 // cellular response to hyperoxia // inferred from electronic annotation /// 0071456 // cellular response to hypoxia // inferred from electronic annotation /// 0071480 // cellular response to gamma radiation // inferred from electronic annotation /// 0071504 // cellular response to heparin // inferred from sequence or structural similarity /// 0071506 // cellular response to mycophenolic acid // inferred from sequence or structural similarity /// 0071873 // response to norepinephrine // inferred from electronic annotation /// 0072110 // glomerular mesangial cell proliferation // inferred from sequence or structural similarity /// 0072303 // positive regulation of glomerular metanephric mesangial cell proliferation // inferred from sequence or structural similarity /// 0090090 // negative regulation of canonical Wnt signaling pathway // inferred from electronic annotation",0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity,0.420059131,0.000800269,TRUE
217077_s_at,GABBR2,9568,ENSG00000136928 /// OTTHUMG00000020345,"gamma-aminobutyric acid (GABA) B receptor, 2",0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // traceable author statement /// 0007194 // negative regulation of adenylate cyclase activity // traceable author statement /// 0007214 // gamma-aminobutyric acid signaling pathway // inferred from direct assay /// 0007268 // synaptic transmission // traceable author statement,0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0038039 // G-protein coupled receptor heterodimeric complex // inferred from physical interaction /// 0043005 // neuron projection // inferred from electronic annotation /// 0045202 // synapse // inferred from electronic annotation /// 0045211 // postsynaptic membrane // inferred from electronic annotation,0.085630895,0.000851173,TRUE
203716_s_at,DPP4,1803,ENSG00000197635 /// OTTHUMG00000132056,dipeptidyl-peptidase 4,0001666 // response to hypoxia // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0010716 // negative regulation of extracellular matrix disassembly // inferred from direct assay /// 0031295 // T cell costimulation // inferred from direct assay /// 0033632 // regulation of cell-cell adhesion mediated by integrin // inferred from direct assay /// 0042110 // T cell activation // inferred from direct assay /// 0043542 // endothelial cell migration // inferred from direct assay,0005576 // extracellular region // inferred from electronic annotation /// 0005765 // lysosomal membrane // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0016324 // apical plasma membrane // inferred from direct assay /// 0030027 // lamellipodium // inferred from direct assay /// 0030054 // cell junction // inferred from electronic annotation /// 0030139 // endocytic vesicle // inferred from direct assay /// 0031258 // lamellipodium membrane // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0045121 // membrane raft // inferred from electronic annotation /// 0046581 // intercellular canaliculus // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0071438 // invadopodium membrane // inferred from direct assay,0.122362094,0.000872352,TRUE
201202_at,PCNA,5111,ENSG00000132646 /// OTTHUMG00000031798,proliferating cell nuclear antigen,"0000077 // DNA damage checkpoint // inferred from electronic annotation /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006272 // leading strand elongation // not recorded /// 0006275 // regulation of DNA replication // inferred from electronic annotation /// 0006281 // DNA repair // non-traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006284 // base-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0006298 // mismatch repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007507 // heart development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0019985 // translesion synthesis // inferred from direct assay /// 0030855 // epithelial cell differentiation // inferred from expression pattern /// 0032077 // positive regulation of deoxyribonuclease activity // inferred from direct assay /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0033993 // response to lipid // inferred from electronic annotation /// 0046686 // response to cadmium ion // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement",0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0030896 // checkpoint clamp complex // inferred from electronic annotation /// 0043596 // nuclear replication fork // inferred from direct assay /// 0043626 // PCNA complex // not recorded /// 0070062 // extracellular vesicular exosome // inferred from direct assay /// 0070557 // PCNA-p21 complex // inferred from direct assay,-0.192189176,0.000886046,TRUE
207175_at,ADIPOQ,9370,ENSG00000181092 /// OTTHUMG00000156521,"adiponectin, C1Q and collagen domain containing","0001666 // response to hypoxia // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0006006 // glucose metabolic process // inferred from sequence or structural similarity /// 0006091 // generation of precursor metabolites and energy // traceable author statement /// 0006635 // fatty acid beta-oxidation // inferred from sequence or structural similarity /// 0007584 // response to nutrient // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from electronic annotation /// 0009744 // response to sucrose // inferred from electronic annotation /// 0009749 // response to glucose // inferred from sequence or structural similarity /// 0009967 // positive regulation of signal transduction // inferred from sequence or structural similarity /// 0010642 // negative regulation of platelet-derived growth factor receptor signaling pathway // inferred from direct assay /// 0010739 // positive regulation of protein kinase A signaling // inferred from direct assay /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred from direct assay /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010906 // regulation of glucose metabolic process // inferred from direct assay /// 0014823 // response to activity // inferred from electronic annotation /// 0014912 // negative regulation of smooth muscle cell migration // inferred from direct assay /// 0019395 // fatty acid oxidation // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0030853 // negative regulation of granulocyte differentiation // inferred from direct assay /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0031953 // negative regulation of protein autophosphorylation // inferred from direct assay /// 0032270 // positive regulation of cellular protein metabolic process // inferred from direct assay /// 0032720 // negative regulation of tumor necrosis factor production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032869 // cellular response to insulin stimulus // inferred from sequence or structural similarity /// 0033034 // positive regulation of myeloid cell apoptotic process // inferred from direct assay /// 0033211 // adiponectin-activated signaling pathway // inferred from electronic annotation /// 0034115 // negative regulation of heterotypic cell-cell adhesion // inferred from direct assay /// 0034383 // low-density lipoprotein particle clearance // inferred from direct assay /// 0034612 // response to tumor necrosis factor // inferred from direct assay /// 0035690 // cellular response to drug // inferred from sequence or structural similarity /// 0042493 // response to drug // inferred from electronic annotation /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0043123 // positive regulation of I-kappaB kinase/NF-kappaB signaling // inferred from sequence or structural similarity /// 0043124 // negative regulation of I-kappaB kinase/NF-kappaB signaling // inferred from direct assay /// 0043407 // negative regulation of MAP kinase activity // inferred from sequence or structural similarity /// 0045471 // response to ethanol // inferred from electronic annotation /// 0045599 // negative regulation of fat cell differentiation // inferred from direct assay /// 0045650 // negative regulation of macrophage differentiation // inferred from direct assay /// 0045715 // negative regulation of low-density lipoprotein particle receptor biosynthetic process // inferred from direct assay /// 0045721 // negative regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0045776 // negative regulation of blood pressure // inferred from direct assay /// 0045777 // positive regulation of blood pressure // inferred from electronic annotation /// 0045860 // positive regulation of protein kinase activity // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045923 // positive regulation of fatty acid metabolic process // inferred from sequence or structural similarity /// 0046326 // positive regulation of glucose import // inferred from sequence or structural similarity /// 0046888 // negative regulation of hormone secretion // inferred from electronic annotation /// 0048662 // negative regulation of smooth muscle cell proliferation // inferred from direct assay /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // non-traceable author statement /// 0050731 // positive regulation of peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0050765 // negative regulation of phagocytosis // inferred from direct assay /// 0050805 // negative regulation of synaptic transmission // inferred from direct assay /// 0050873 // brown fat cell differentiation // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051384 // response to glucocorticoid // inferred from electronic annotation /// 0051899 // membrane depolarization // inferred from electronic annotation /// 0060081 // membrane hyperpolarization // inferred from electronic annotation /// 0070208 // protein heterotrimerization // inferred from electronic annotation /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070543 // response to linoleic acid // inferred from electronic annotation /// 0070994 // detection of oxidative stress // inferred from sequence or structural similarity /// 0071320 // cellular response to cAMP // inferred from electronic annotation /// 0071639 // positive regulation of monocyte chemotactic protein-1 production // inferred from direct assay /// 0071872 // cellular response to epinephrine stimulus // inferred from electronic annotation /// 0072659 // protein localization to plasma membrane // inferred from direct assay /// 0090317 // negative regulation of intracellular protein transport // inferred from direct assay /// 1900121 // negative regulation of receptor binding // inferred from direct assay /// 2000279 // negative regulation of DNA biosynthetic process // inferred from direct assay /// 2000467 // positive regulation of glycogen (starch) synthase activity // inferred from sequence or structural similarity /// 2000478 // positive regulation of metanephric glomerular visceral epithelial cell development // inferred from sequence or structural similarity /// 2000481 // positive regulation of cAMP-dependent protein kinase activity // inferred from direct assay /// 2000534 // positive regulation of renal albumin absorption // inferred from direct assay /// 2000584 // negative regulation of platelet-derived growth factor receptor-alpha signaling pathway // inferred from sequence or structural similarity /// 2000590 // negative regulation of metanephric mesenchymal cell migration // inferred from sequence or structural similarity",0005576 // extracellular region // traceable author statement /// 0005581 // collagen trimer // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from sequence or structural similarity /// 0009986 // cell surface // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.062654614,0.000902967,TRUE
204825_at,MELK,9833,ENSG00000165304 /// OTTHUMG00000019906,maternal embryonic leucine zipper kinase,0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from direct assay /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0008631 // intrinsic apoptotic signaling pathway in response to oxidative stress // inferred from electronic annotation /// 0009103 // lipopolysaccharide biosynthetic process // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0061351 // neural precursor cell proliferation // inferred from sequence or structural similarity,0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005938 // cell cortex // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation,-0.259072764,0.000946132,TRUE
211048_s_at,PDIA4,9601,ENSG00000155660 /// OTTHUMG00000150248,"protein disulfide isomerase family A, member 4",0006457 // protein folding // not recorded /// 0006662 // glycerol ether metabolic process // inferred from electronic annotation /// 0009306 // protein secretion // traceable author statement /// 0034976 // response to endoplasmic reticulum stress // not recorded /// 0045454 // cell redox homeostasis // inferred from electronic annotation /// 0061077 // chaperone-mediated protein folding // inferred from sequence or structural similarity,0005783 // endoplasmic reticulum // not recorded /// 0005788 // endoplasmic reticulum lumen // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0042470 // melanosome // inferred from electronic annotation,-0.220978135,0.000996616,TRUE
212851_at,DCUN1D4,23142,ENSG00000109184 /// OTTHUMG00000128700,"DCN1, defective in cullin neddylation 1, domain containing 4",---,0005634 // nucleus // inferred from direct assay,-0.224846828,0.001007373,TRUE
220186_s_at,CDHR2,54825,ENSG00000074276 /// OTTHUMG00000163229,cadherin-related family member 2,0007155 // cell adhesion // inferred from direct assay /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0030308 // negative regulation of cell growth // inferred from direct assay,0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0016324 // apical plasma membrane // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.053254922,0.001022137,TRUE
213056_at,FRMD4B,23150,ENSG00000114541 /// OTTHUMG00000158772,FERM domain containing 4B,0090162 // establishment of epithelial cell polarity // inferred from electronic annotation,0001726 // ruffle // inferred from electronic annotation /// 0005615 // extracellular space // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation,0.303348116,0.001079951,TRUE
204822_at,TTK,7272,ENSG00000112742 /// OTTHUMG00000015088,TTK protein kinase,0006468 // protein phosphorylation // inferred from electronic annotation /// 0007051 // spindle organization // traceable author statement /// 0007052 // mitotic spindle organization // traceable author statement /// 0007093 // mitotic cell cycle checkpoint // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0010862 // positive regulation of pathway-restricted SMAD protein phosphorylation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // traceable author statement /// 0051304 // chromosome separation // inferred from electronic annotation,0005819 // spindle // traceable author statement /// 0016020 // membrane // inferred from direct assay,-0.279496807,0.001115168,TRUE
209101_at,CTGF,1490,ENSG00000118523 /// OTTHUMG00000015573,connective tissue growth factor,0001502 // cartilage condensation // inferred from electronic annotation /// 0001503 // ossification // inferred from electronic annotation /// 0001525 // angiogenesis // inferred from electronic annotation /// 0001558 // regulation of cell growth // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from electronic annotation /// 0006260 // DNA replication // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0007160 // cell-matrix adhesion // inferred from electronic annotation /// 0007229 // integrin-mediated signaling pathway // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from electronic annotation /// 0008543 // fibroblast growth factor receptor signaling pathway // inferred from electronic annotation /// 0008544 // epidermis development // traceable author statement /// 0009611 // response to wounding // traceable author statement /// 0009749 // response to glucose // inferred from electronic annotation /// 0010260 // organ senescence // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0010628 // positive regulation of gene expression // inferred from electronic annotation /// 0010629 // negative regulation of gene expression // inferred from electronic annotation /// 0010942 // positive regulation of cell death // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0016477 // cell migration // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0032330 // regulation of chondrocyte differentiation // inferred from electronic annotation /// 0032355 // response to estradiol // inferred from electronic annotation /// 0032967 // positive regulation of collagen biosynthetic process // inferred from electronic annotation /// 0034059 // response to anoxia // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0035988 // chondrocyte proliferation // inferred from electronic annotation /// 0043200 // response to amino acid // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0045597 // positive regulation of cell differentiation // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0050867 // positive regulation of cell activation // inferred from electronic annotation /// 0051385 // response to mineralocorticoid // inferred from electronic annotation /// 0051496 // positive regulation of stress fiber assembly // inferred from direct assay /// 0060401 // cytosolic calcium ion transport // inferred from electronic annotation /// 0060452 // positive regulation of cardiac muscle contraction // inferred from electronic annotation /// 0060548 // negative regulation of cell death // inferred from electronic annotation /// 0070278 // extracellular matrix constituent secretion // inferred from electronic annotation /// 0070318 // positive regulation of G0 to G1 transition // inferred from electronic annotation /// 0070374 // positive regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation,0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from direct assay /// 0005801 // cis-Golgi network // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0005886 // plasma membrane // traceable author statement /// 0005938 // cell cortex // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from electronic annotation,0.438192214,0.001112449,TRUE
203145_at,SPAG5,10615,ENSG00000076382 /// OTTHUMG00000166586,sperm associated antigen 5,0000070 // mitotic sister chromatid segregation // inferred from mutant phenotype /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // inferred from mutant phenotype /// 0007051 // spindle organization // non-traceable author statement /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051988 // regulation of attachment of spindle microtubules to kinetochore // inferred from mutant phenotype,"0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000922 // spindle pole // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from electronic annotation /// 0030496 // midbody // inferred from electronic annotation /// 0035371 // microtubule plus-end // inferred from direct assay /// 0072686 // mitotic spindle // inferred from direct assay",-0.200922452,0.001131239,TRUE
202768_at,FOSB,2354,ENSG00000125740 /// OTTHUMG00000182122,FBJ murine osteosarcoma viral oncogene homolog B,"0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007275 // multicellular organismal development // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007610 // behavior // traceable author statement /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043278 // response to morphine // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation",0005634 // nucleus // inferred from electronic annotation,0.38736009,0.00115771,TRUE
203920_at,NR1H3,10062,ENSG00000025434 /// OTTHUMG00000150628,"nuclear receptor subfamily 1, group H, member 3","0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0010745 // negative regulation of macrophage derived foam cell differentiation // inferred by curator /// 0010867 // positive regulation of triglyceride biosynthetic process // inferred from mutant phenotype /// 0010870 // positive regulation of receptor biosynthetic process // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from direct assay /// 0010875 // positive regulation of cholesterol efflux // inferred from mutant phenotype /// 0010887 // negative regulation of cholesterol storage // inferred from mutant phenotype /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0032270 // positive regulation of cellular protein metabolic process // inferred from mutant phenotype /// 0032369 // negative regulation of lipid transport // inferred from mutant phenotype /// 0032376 // positive regulation of cholesterol transport // inferred from direct assay /// 0032570 // response to progesterone // inferred from direct assay /// 0034145 // positive regulation of toll-like receptor 4 signaling pathway // inferred from direct assay /// 0042632 // cholesterol homeostasis // inferred from sequence or structural similarity /// 0042752 // regulation of circadian rhythm // traceable author statement /// 0043031 // negative regulation of macrophage activation // inferred from sequence or structural similarity /// 0043277 // apoptotic cell clearance // inferred from mutant phenotype /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // inferred from electronic annotation /// 0045723 // positive regulation of fatty acid biosynthetic process // inferred from mutant phenotype /// 0045861 // negative regulation of proteolysis // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from mutant phenotype /// 0048550 // negative regulation of pinocytosis // inferred from mutant phenotype /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0051006 // positive regulation of lipoprotein lipase activity // inferred from mutant phenotype /// 0055088 // lipid homeostasis // inferred from sequence or structural similarity /// 0055092 // sterol homeostasis // inferred from sequence or structural similarity /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // non-traceable author statement /// 0070328 // triglyceride homeostasis // inferred from sequence or structural similarity /// 0071222 // cellular response to lipopolysaccharide // inferred from direct assay /// 0090188 // negative regulation of pancreatic juice secretion // inferred from sequence or structural similarity /// 0090341 // negative regulation of secretion of lysosomal enzymes // inferred from sequence or structural similarity /// 2000188 // regulation of cholesterol homeostasis // inferred from sequence or structural similarity /// 2000189 // positive regulation of cholesterol homeostasis // inferred from direct assay",0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement,-0.212603566,0.001163603,TRUE
213769_at,KSR1,8844,ENSG00000141068 /// OTTHUMG00000132051,kinase suppressor of ras 1,0006468 // protein phosphorylation // inferred from electronic annotation /// 0007265 // Ras protein signal transduction // non-traceable author statement /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043410 // positive regulation of MAPK cascade // inferred from electronic annotation,0005622 // intracellular // non-traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation,0.044153017,0.00118755,TRUE
201755_at,MCM5,4174,ENSG00000100297 /// OTTHUMG00000150961,minichromosome maintenance complex component 5,0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation,0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay,-0.167732454,0.001216198,TRUE
205908_s_at,OMD,4958,ENSG00000127083 /// OTTHUMG00000020225,osteomodulin,0005975 // carbohydrate metabolic process // traceable author statement /// 0007155 // cell adhesion // inferred from electronic annotation /// 0018146 // keratan sulfate biosynthetic process // traceable author statement /// 0030203 // glycosaminoglycan metabolic process // traceable author statement /// 0042339 // keratan sulfate metabolic process // traceable author statement /// 0042340 // keratan sulfate catabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement,0005576 // extracellular region // traceable author statement /// 0005578 // proteinaceous extracellular matrix // inferred from electronic annotation /// 0005796 // Golgi lumen // traceable author statement /// 0043202 // lysosomal lumen // traceable author statement,0.078196154,0.001238545,TRUE
217980_s_at,MRPL16,54948,ENSG00000166902 /// OTTHUMG00000167410,mitochondrial ribosomal protein L16,0006412 // translation // inferred from electronic annotation,0005739 // mitochondrion // inferred from electronic annotation /// 0005840 // ribosome // inferred from electronic annotation /// 0030529 // ribonucleoprotein complex // inferred from electronic annotation,-0.161379555,0.001250971,TRUE
212099_at,RHOB,388,ENSG00000143878 /// OTTHUMG00000090755,ras homolog family member B,0000910 // cytokinesis // inferred from mutant phenotype /// 0001525 // angiogenesis // inferred from electronic annotation /// 0006184 // GTP catabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006927 // transformed cell apoptotic process // inferred from sequence or structural similarity /// 0007155 // cell adhesion // inferred from sequence or structural similarity /// 0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007266 // Rho protein signal transduction // traceable author statement /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008333 // endosome to lysosome transport // inferred from direct assay /// 0015031 // protein transport // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030168 // platelet activation // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045766 // positive regulation of angiogenesis // inferred from sequence or structural similarity /// 0045786 // negative regulation of cell cycle // inferred from sequence or structural similarity /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0070301 // cellular response to hydrogen peroxide // inferred from direct assay /// 0071479 // cellular response to ionizing radiation // inferred from direct assay,0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from sequence or structural similarity /// 0005768 // endosome // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0010008 // endosome membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031902 // late endosome membrane // inferred from electronic annotation /// 0032154 // cleavage furrow // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.270240962,0.001308909,TRUE
208078_s_at,SIK1,150094,ENSG00000142178 /// OTTHUMG00000086874,salt-inducible kinase 1,"0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002028 // regulation of sodium ion transport // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // inferred from sequence or structural similarity /// 0006955 // immune response // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007346 // regulation of mitotic cell cycle // inferred from sequence or structural similarity /// 0007389 // pattern specification process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007417 // central nervous system development // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0010464 // regulation of mesenchymal cell proliferation // inferred from electronic annotation /// 0010830 // regulation of myotube differentiation // inferred from sequence or structural similarity /// 0010868 // negative regulation of triglyceride biosynthetic process // inferred from sequence or structural similarity /// 0014823 // response to activity // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0017015 // regulation of transforming growth factor beta receptor signaling pathway // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030857 // negative regulation of epithelial cell differentiation // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0032792 // negative regulation of CREB transcription factor activity // inferred from sequence or structural similarity /// 0033081 // regulation of T cell differentiation in thymus // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from direct assay /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0043276 // anoikis // inferred from electronic annotation /// 0045595 // regulation of cell differentiation // inferred from sequence or structural similarity /// 0045666 // positive regulation of neuron differentiation // inferred from electronic annotation /// 0045666 // positive regulation of neuron differentiation // inferred from sequence or structural similarity /// 0045721 // negative regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from direct assay /// 0048513 // organ development // inferred from electronic annotation /// 0048596 // embryonic camera-type eye morphogenesis // inferred from electronic annotation /// 0048598 // embryonic morphogenesis // inferred from electronic annotation /// 0048704 // embryonic skeletal system morphogenesis // inferred from electronic annotation /// 0048752 // semicircular canal morphogenesis // inferred from electronic annotation /// 0051150 // regulation of smooth muscle cell differentiation // inferred from electronic annotation /// 0051216 // cartilage development // inferred from electronic annotation /// 0055007 // cardiac muscle cell differentiation // inferred from sequence or structural similarity /// 0071230 // cellular response to amino acid stimulus // inferred from electronic annotation /// 0071560 // cellular response to transforming growth factor beta stimulus // inferred from electronic annotation /// 0090103 // cochlea morphogenesis // inferred from electronic annotation /// 2000210 // positive regulation of anoikis // inferred from mutant phenotype",0005634 // nucleus // inferred from direct assay /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005737 // cytoplasm // inferred from sequence or structural similarity /// 0005829 // cytosol // inferred from electronic annotation,0.279775771,0.001401055,TRUE
212208_at,MED13L,23389,ENSG00000123066 /// OTTHUMG00000169404,mediator complex subunit 13-like,"0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation",0005634 // nucleus // inferred from electronic annotation /// 0016592 // mediator complex // inferred from electronic annotation,0.180005335,0.001433576,TRUE
221255_s_at,EMC6,83460,ENSG00000127774 /// OTTHUMG00000180187,ER membrane protein complex subunit 6,---,0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay,-0.129157874,0.001470995,TRUE
204739_at,CENPC,1060,ENSG00000145241 /// OTTHUMG00000160735,centromere protein C,0000278 // mitotic cell cycle // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from mutant phenotype /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051382 // kinetochore assembly // inferred from mutant phenotype,"0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000777 // condensed chromosome kinetochore // inferred from electronic annotation /// 0000780 // condensed nuclear chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005721 // centromeric heterochromatin // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement",-0.168476572,0.001466581,TRUE
205501_at,PDE10A,10846,ENSG00000112541 /// OTTHUMG00000015986,phosphodiesterase 10A,0006198 // cAMP catabolic process // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010738 // regulation of protein kinase A signaling // inferred from electronic annotation /// 0043949 // regulation of cAMP-mediated signaling // inferred from electronic annotation /// 0046069 // cGMP catabolic process // inferred from electronic annotation,0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement,0.067452494,0.001488231,TRUE
202613_at,CTPS1,1503,ENSG00000171793 /// OTTHUMG00000005712,CTP synthase 1,0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006241 // CTP biosynthetic process // inferred from direct assay /// 0006541 // glutamine metabolic process // inferred from electronic annotation /// 0015949 // nucleobase-containing small molecule interconversion // traceable author statement /// 0042493 // response to drug // traceable author statement /// 0044210 // 'de novo' CTP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement,0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from direct assay,-0.213189821,0.001493297,TRUE
218626_at,EIF4ENIF1,56478,ENSG00000184708 /// OTTHUMG00000030793,eukaryotic translation initiation factor 4E nuclear import factor 1,0006413 // translational initiation // inferred from electronic annotation /// 0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation,0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016605 // PML body // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay,-0.156548119,0.001505167,TRUE
218663_at,NCAPG,64151,ENSG00000109805 /// OTTHUMG00000128539,"non-SMC condensin I complex, subunit G",0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0007076 // mitotic chromosome condensation // non-traceable author statement /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation,0000793 // condensed chromosome // inferred from electronic annotation /// 0000796 // condensin complex // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005813 // centrosome // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0015629 // actin cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from direct assay,-0.245439402,0.001507664,TRUE
211754_s_at,SLC25A17,10478,ENSG00000100372 /// OTTHUMG00000151139,"solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17",0001561 // fatty acid alpha-oxidation // traceable author statement /// 0006635 // fatty acid beta-oxidation // inferred from genetic interaction /// 0006810 // transport // inferred from electronic annotation /// 0006839 // mitochondrial transport // inferred from electronic annotation /// 0015866 // ADP transport // inferred from direct assay /// 0015867 // ATP transport // inferred from genetic interaction /// 0015908 // fatty acid transport // inferred from genetic interaction /// 0035349 // coenzyme A transmembrane transport // inferred from direct assay /// 0035350 // FAD transmembrane transport // inferred from direct assay /// 0043132 // NAD transport // inferred from direct assay /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055085 // transmembrane transport // inferred from electronic annotation /// 0080121 // AMP transport // inferred from direct assay /// 1901679 // nucleotide transmembrane transport // inferred from direct assay,0005737 // cytoplasm // inferred from electronic annotation /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005778 // peroxisomal membrane // traceable author statement /// 0005779 // integral component of peroxisomal membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031966 // mitochondrial membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay,-0.14072808,0.001523095,TRUE
201487_at,CTSC,1075,ENSG00000109861 /// OTTHUMG00000167290,cathepsin C,0001913 // T cell mediated cytotoxicity // inferred from electronic annotation /// 0006508 // proteolysis // inferred from direct assay /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007568 // aging // inferred from electronic annotation /// 0010033 // response to organic substance // inferred from electronic annotation /// 1903052 // positive regulation of proteolysis involved in cellular protein catabolic process // inferred from sequence or structural similarity /// 2001235 // positive regulation of apoptotic signaling pathway // inferred from electronic annotation,0005615 // extracellular space // inferred from direct assay /// 0005764 // lysosome // inferred from sequence or structural similarity /// 0005764 // lysosome // traceable author statement /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay,-0.219860421,0.001531644,TRUE
212256_at,GALNT10,55568,ENSG00000164574 /// OTTHUMG00000130145,polypeptide N-acetylgalactosaminyltransferase 10,0006486 // protein glycosylation // inferred from electronic annotation /// 0006493 // protein O-linked glycosylation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0016266 // O-glycan processing // traceable author statement /// 0043687 // post-translational protein modification // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement,0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation,0.202486013,0.001556816,TRUE
209189_at,FOS,2353,ENSG00000170345 /// OTTHUMG00000171774,FBJ murine osteosarcoma viral oncogene homolog,"0001661 // conditioned taste aversion // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0002756 // MyD88-independent toll-like receptor signaling pathway // traceable author statement /// 0006306 // DNA methylation // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0006954 // inflammatory response // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // inferred from direct assay /// 0007399 // nervous system development // inferred from electronic annotation /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007568 // aging // inferred from electronic annotation /// 0009409 // response to cold // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009629 // response to gravity // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030431 // sleep // inferred from electronic annotation /// 0031668 // cellular response to extracellular stimulus // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034138 // toll-like receptor 3 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0034146 // toll-like receptor 5 signaling pathway // traceable author statement /// 0034162 // toll-like receptor 9 signaling pathway // traceable author statement /// 0034166 // toll-like receptor 10 signaling pathway // traceable author statement /// 0034614 // cellular response to reactive oxygen species // inferred from direct assay /// 0035666 // TRIF-dependent toll-like receptor signaling pathway // traceable author statement /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042493 // response to drug // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045672 // positive regulation of osteoclast differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0051090 // regulation of sequence-specific DNA binding transcription factor activity // traceable author statement /// 0051403 // stress-activated MAPK cascade // traceable author statement /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0060395 // SMAD protein signal transduction // inferred from direct assay /// 0071277 // cellular response to calcium ion // inferred from electronic annotation",0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation,0.481134864,0.001564395,TRUE
221206_at,PMS2 /// PMS2CL,5395 /// 441194,ENSG00000187953 /// OTTHUMG00000151857,PMS2 postmeiotic segregation increased 2 (S. cerevisiae) /// PMS2 C-terminal like pseudogene,0006200 // ATP catabolic process // not recorded /// 0006281 // DNA repair // inferred from electronic annotation /// 0006298 // mismatch repair // inferred from direct assay /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0016446 // somatic hypermutation of immunoglobulin genes // not recorded /// 0016447 // somatic recombination of immunoglobulin gene segments // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0090305 // nucleic acid phosphodiester bond hydrolysis // inferred from electronic annotation,0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0032300 // mismatch repair complex // inferred from electronic annotation /// 0032389 // MutLalpha complex // not recorded,0.176942068,0.001582559,TRUE
205212_s_at,ACAP1,9744,ENSG00000072818 /// OTTHUMG00000102199,"ArfGAP with coiled-coil, ankyrin repeat and PH domains 1",0006810 // transport // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0032312 // regulation of ARF GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation,0005768 // endosome // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0055038 // recycling endosome membrane // inferred from electronic annotation,-0.067696705,0.001617481,TRUE
202107_s_at,MCM2,4171,ENSG00000073111 /// OTTHUMG00000159637,minichromosome maintenance complex component 2,0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from mutant phenotype /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006334 // nucleosome assembly // inferred from electronic annotation /// 0007049 // cell cycle // traceable author statement /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0071353 // cellular response to interleukin-4 // inferred from electronic annotation,0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005664 // nuclear origin of replication recognition complex // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay,-0.202062865,0.001619059,TRUE
203302_at,DCK,1633,ENSG00000156136 /// OTTHUMG00000129908,deoxycytidine kinase,0006139 // nucleobase-containing compound metabolic process // inferred from electronic annotation /// 0006144 // purine nucleobase metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006220 // pyrimidine nucleotide metabolic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from direct assay /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0016310 // phosphorylation // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0043101 // purine-containing compound salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement,0005634 // nucleus // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement,-0.210194637,0.001615288,TRUE
218402_s_at,HPS4,89781,ENSG00000100099 /// OTTHUMG00000030459,Hermansky-Pudlak syndrome 4,0006605 // protein targeting // inferred from direct assay /// 0006996 // organelle organization // inferred from electronic annotation /// 0007040 // lysosome organization // inferred from direct assay /// 0007596 // blood coagulation // inferred from electronic annotation /// 0007599 // hemostasis // traceable author statement /// 0030318 // melanocyte differentiation // inferred from electronic annotation /// 0048075 // positive regulation of eye pigmentation // traceable author statement /// 0050821 // protein stabilization // inferred from physical interaction,0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0031085 // BLOC-3 complex // inferred from physical interaction /// 0042470 // melanosome // inferred from direct assay /// 0042827 // platelet dense granule // inferred from direct assay,-0.126375597,0.001752782,TRUE
213206_at,GOSR2,9570,---,golgi SNAP receptor complex member 2,0006810 // transport // inferred from electronic annotation /// 0006888 // ER to Golgi vesicle-mediated transport // traceable author statement /// 0006987 // activation of signaling protein activity involved in unfolded protein response // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0016192 // vesicle-mediated transport // inferred from electronic annotation /// 0030968 // endoplasmic reticulum unfolded protein response // traceable author statement /// 0044267 // cellular protein metabolic process // traceable author statement /// 0061025 // membrane fusion // traceable author statement,0000139 // Golgi membrane // traceable author statement /// 0005794 // Golgi apparatus // inferred from electronic annotation /// 0005795 // Golgi stack // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation,-0.111400419,0.001765315,TRUE
208672_s_at,SRSF3,6428,ENSG00000112081 /// OTTHUMG00000014599,serine/arginine-rich splicing factor 3,"0000398 // mRNA splicing, via spliceosome // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006369 // termination of RNA polymerase II transcription // traceable author statement /// 0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0031124 // mRNA 3'-end processing // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation",0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation,-0.07476598,0.001771312,TRUE
203483_at,SEMA4G,57715,ENSG00000095539 /// OTTHUMG00000018922,"sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G",0007275 // multicellular organismal development // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation,0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation,0.049179782,0.001795643,TRUE
201873_s_at,ABCE1,6059,ENSG00000164163 /// OTTHUMG00000161478,"ATP-binding cassette, sub-family E (OABP), member 1",0006200 // ATP catabolic process // inferred from electronic annotation /// 0006401 // RNA catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0009615 // response to virus // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement,0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from direct assay,-0.147710637,0.001797085,TRUE
200079_s_at,KARS,3735,ENSG00000065427 /// OTTHUMG00000137609,lysyl-tRNA synthetase,0006412 // translation // inferred from electronic annotation /// 0006418 // tRNA aminoacylation for protein translation // traceable author statement /// 0006430 // lysyl-tRNA aminoacylation // inferred from direct assay /// 0008033 // tRNA processing // non-traceable author statement /// 0008219 // cell death // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0015966 // diadenosine tetraphosphate biosynthetic process // inferred from electronic annotation /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation,0005576 // extracellular region // inferred from electronic annotation /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from electronic annotation /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0017101 // aminoacyl-tRNA synthetase multienzyme complex // inferred from electronic annotation,-0.133158838,0.001878085,TRUE
222360_at,DPH5,51611,ENSG00000117543 /// OTTHUMG00000010829,diphthamide biosynthesis 5,0008152 // metabolic process // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // inferred from electronic annotation /// 0017183 // peptidyl-diphthamide biosynthetic process from peptidyl-histidine // non-traceable author statement /// 0032259 // methylation // inferred from electronic annotation,---,0.087592725,0.001904621,TRUE
202706_s_at,UMPS,7372,ENSG00000114491 /// OTTHUMG00000159431,uridine monophosphate synthetase,0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006207 // 'de novo' pyrimidine nucleobase biosynthetic process // inferred from electronic annotation /// 0006221 // pyrimidine nucleotide biosynthetic process // inferred from electronic annotation /// 0006222 // UMP biosynthetic process // inferred from direct assay /// 0007565 // female pregnancy // inferred from electronic annotation /// 0007595 // lactation // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0009116 // nucleoside metabolic process // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from electronic annotation /// 0044205 // 'de novo' UMP biosynthetic process // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0046134 // pyrimidine nucleoside biosynthetic process // traceable author statement /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement,0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement,-0.137091824,0.002009022,TRUE
204126_s_at,CDC45,8318,ENSG00000093009 /// OTTHUMG00000150386,cell division cycle 45,0000076 // DNA replication checkpoint // traceable author statement /// 0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000083 // regulation of transcription involved in G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation,0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005813 // centrosome // inferred from direct assay,-0.223499844,0.002006177,TRUE
210334_x_at,BIRC5,332,ENSG00000089685 /// OTTHUMG00000177505,baculoviral IAP repeat containing 5,"0000086 // G2/M transition of mitotic cell cycle // inferred from direct assay /// 0000226 // microtubule cytoskeleton organization // inferred from electronic annotation /// 0000278 // mitotic cell cycle // traceable author statement /// 0000910 // cytokinesis // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006508 // proteolysis // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007059 // chromosome segregation // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007067 // mitotic nuclear division // traceable author statement /// 0007166 // cell surface receptor signaling pathway // non-traceable author statement /// 0008284 // positive regulation of cell proliferation // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0010466 // negative regulation of peptidase activity // inferred from electronic annotation /// 0010951 // negative regulation of endopeptidase activity // inferred from electronic annotation /// 0031503 // protein complex localization // inferred from mutant phenotype /// 0031536 // positive regulation of exit from mitosis // inferred from mutant phenotype /// 0031577 // spindle checkpoint // inferred from mutant phenotype /// 0043066 // negative regulation of apoptotic process // inferred from direct assay /// 0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from direct assay /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from mutant phenotype /// 0043524 // negative regulation of neuron apoptotic process // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0045931 // positive regulation of mitotic cell cycle // inferred from mutant phenotype /// 0051301 // cell division // inferred from mutant phenotype /// 0051303 // establishment of chromosome localization // inferred from mutant phenotype","0000228 // nuclear chromosome // inferred from direct assay /// 0000775 // chromosome, centromeric region // inferred from direct assay /// 0000776 // kinetochore // inferred from electronic annotation /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005814 // centriole // inferred from direct assay /// 0005819 // spindle // inferred from electronic annotation /// 0005829 // cytosol // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005876 // spindle microtubule // inferred from direct assay /// 0005881 // cytoplasmic microtubule // inferred from direct assay /// 0030496 // midbody // inferred from direct assay /// 0031021 // interphase microtubule organizing center // inferred from direct assay /// 0032133 // chromosome passenger complex // inferred from physical interaction",-0.243073302,0.002072255,TRUE
211869_at,---,---,---,---,0001935 // endothelial cell proliferation // inferred from expression pattern /// 0001974 // blood vessel remodeling // inferred from mutant phenotype /// 0006801 // superoxide metabolic process // inferred from sequence or structural similarity /// 0006809 // nitric oxide biosynthetic process // inferred from direct assay /// 0006809 // nitric oxide biosynthetic process // inferred from electronic annotation /// 0006809 // nitric oxide biosynthetic process // traceable author statement /// 0006954 // inflammatory response // --- /// 0007165 // signal transduction // inferred from direct assay /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // inferred from direct assay /// 0007263 // nitric oxide mediated signal transduction // --- /// 0007568 // aging // inferred from expression pattern /// 0008016 // regulation of heart contraction // inferred from mutant phenotype /// 0008217 // regulation of blood pressure // inferred from mutant phenotype /// 0009612 // response to mechanical stimulus // inferred from expression pattern /// 0009725 // response to hormone // inferred from expression pattern /// 0014823 // response to activity // inferred from expression pattern /// 0016137 // glycoside metabolic process // inferred from expression pattern /// 0018119 // peptidyl-cysteine S-nitrosylation // inferred from sequence or structural similarity /// 0019934 // cGMP-mediated signaling // inferred from direct assay /// 0031284 // positive regulation of guanylate cyclase activity // --- /// 0032355 // response to estradiol // inferred from expression pattern /// 0032496 // response to lipopolysaccharide // inferred from expression pattern /// 0034612 // response to tumor necrosis factor // inferred from mutant phenotype /// 0035556 // intracellular signal transduction // inferred from mutant phenotype /// 0035902 // response to immobilization stress // inferred from expression pattern /// 0042742 // defense response to bacterium // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0045776 // negative regulation of blood pressure // --- /// 0045859 // regulation of protein kinase activity // inferred from direct assay /// 0045909 // positive regulation of vasodilation // --- /// 0048384 // retinoic acid receptor signaling pathway // inferred from expression pattern /// 0050829 // defense response to Gram-negative bacterium // inferred from expression pattern /// 0055114 // oxidation-reduction process // inferred from electronic annotation /// 0071222 // cellular response to lipopolysaccharide // inferred from expression pattern /// 0071285 // cellular response to lithium ion // inferred from expression pattern /// 0071305 // cellular response to vitamin D // inferred from expression pattern /// 0071347 // cellular response to interleukin-1 // inferred from expression pattern /// 0071356 // cellular response to tumor necrosis factor // inferred from expression pattern /// 0071461 // cellular response to redox state // inferred from expression pattern /// 0071548 // response to dexamethasone // inferred from expression pattern,0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005829 // cytosol // --- /// 0005829 // cytosol // inferred from direct assay /// 0012506 // vesicle membrane // inferred from direct assay /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay,-0.045175631,0.002135444,TRUE
213817_at,IRAK3,11213,ENSG00000090376 /// OTTHUMG00000169002,interleukin-1 receptor-associated kinase 3,0001960 // negative regulation of cytokine-mediated signaling pathway // inferred by curator /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006468 // protein phosphorylation // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0009615 // response to virus // inferred by curator /// 0010933 // positive regulation of macrophage tolerance induction // inferred from sequence or structural similarity /// 0010936 // negative regulation of macrophage cytokine production // inferred from sequence or structural similarity /// 0016310 // phosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // inferred from sequence or structural similarity /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0032494 // response to peptidoglycan // inferred from sequence or structural similarity /// 0032496 // response to lipopolysaccharide // inferred from sequence or structural similarity /// 0032695 // negative regulation of interleukin-12 production // inferred from mutant phenotype /// 0032695 // negative regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032715 // negative regulation of interleukin-6 production // inferred from mutant phenotype /// 0032715 // negative regulation of interleukin-6 production // inferred from sequence or structural similarity /// 0032720 // negative regulation of tumor necrosis factor production // inferred from mutant phenotype /// 0034122 // negative regulation of toll-like receptor signaling pathway // inferred from sequence or structural similarity /// 0042177 // negative regulation of protein catabolic process // inferred from mutant phenotype /// 0043242 // negative regulation of protein complex disassembly // inferred from mutant phenotype /// 0043244 // regulation of protein complex disassembly // inferred from sequence or structural similarity /// 0043330 // response to exogenous dsRNA // inferred from sequence or structural similarity /// 0043407 // negative regulation of MAP kinase activity // inferred from mutant phenotype /// 0045824 // negative regulation of innate immune response // inferred from sequence or structural similarity /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from mutant phenotype /// 0070498 // interleukin-1-mediated signaling pathway // inferred from mutant phenotype /// 0070555 // response to interleukin-1 // inferred from mutant phenotype,0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay,-0.079437281,0.002173294,TRUE
219282_s_at,TRPV2,51393,ENSG00000187688 /// OTTHUMG00000058989,"transient receptor potential cation channel, subfamily V, member 2",0006810 // transport // traceable author statement /// 0006811 // ion transport // inferred from electronic annotation /// 0006816 // calcium ion transport // inferred from electronic annotation /// 0007600 // sensory perception // traceable author statement /// 0009266 // response to temperature stimulus // inferred from direct assay /// 0009408 // response to heat // inferred from electronic annotation /// 0034220 // ion transmembrane transport // traceable author statement /// 0045773 // positive regulation of axon extension // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement /// 0070588 // calcium ion transmembrane transport // traceable author statement /// 0090280 // positive regulation of calcium ion import // inferred from electronic annotation,0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from electronic annotation /// 0012505 // endomembrane system // inferred from electronic annotation /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0032584 // growth cone membrane // inferred from electronic annotation /// 0042470 // melanosome // inferred from electronic annotation /// 0044295 // axonal growth cone // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation,-0.076577171,0.002173087,TRUE
205665_at,TSPAN9,10867,ENSG00000011105 /// OTTHUMG00000150333,tetraspanin 9,---,0005887 // integral component of plasma membrane // traceable author statement /// 0016020 // membrane // traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation,0.103210488,0.002185204,TRUE
202553_s_at,SYF2,25949,ENSG00000117614 /// OTTHUMG00000043610,SYF2 pre-mRNA-splicing factor,"0000075 // cell cycle checkpoint // inferred from electronic annotation /// 0000398 // mRNA splicing, via spliceosome // inferred by curator /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006397 // mRNA processing // inferred from electronic annotation /// 0007369 // gastrulation // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0048568 // embryonic organ development // inferred from electronic annotation",0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005681 // spliceosomal complex // inferred from electronic annotation /// 0071013 // catalytic step 2 spliceosome // inferred from direct assay,0.118790145,0.002187799,TRUE
220043_s_at,MFI2,4241,ENSG00000163975 /// OTTHUMG00000155518,antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5,0001558 // regulation of cell growth // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0006811 // ion transport // inferred from electronic annotation /// 0006826 // iron ion transport // inferred from electronic annotation /// 0006879 // cellular iron ion homeostasis // inferred from electronic annotation /// 0010756 // positive regulation of plasminogen activation // inferred from direct assay /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0055072 // iron ion homeostasis // inferred from electronic annotation /// 0090091 // positive regulation of extracellular matrix disassembly // inferred from direct assay /// 0097286 // iron ion import // inferred from mutant phenotype /// 1900025 // negative regulation of substrate adhesion-dependent cell spreading // inferred from direct assay,0005576 // extracellular region // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031225 // anchored component of membrane // inferred from electronic annotation /// 0046658 // anchored component of plasma membrane // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.053963136,0.00220188,TRUE
203437_at,TMEM11,8834,ENSG00000178307 /// OTTHUMG00000178971,transmembrane protein 11,0007005 // mitochondrion organization // inferred from mutant phenotype,0005739 // mitochondrion // inferred from electronic annotation /// 0005743 // mitochondrial inner membrane // inferred from electronic annotation /// 0005887 // integral component of plasma membrane // non-traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031305 // integral component of mitochondrial inner membrane // inferred from direct assay,-0.096399511,0.002209266,TRUE
203740_at,MPHOSPH6,10200,ENSG00000135698 /// OTTHUMG00000137632,M-phase phosphoprotein 6,0000087 // mitotic M phase // traceable author statement /// 0000460 // maturation of 5.8S rRNA // inferred from mutant phenotype /// 0006364 // rRNA processing // inferred from electronic annotation,0000176 // nuclear exosome (RNase complex) // traceable author statement /// 0000178 // exosome (RNase complex) // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay,-0.164283651,0.002219067,TRUE
218333_at,DERL2,51009,ENSG00000072849 /// OTTHUMG00000102040,derlin 2,"0001967 // suckling behavior // inferred from electronic annotation /// 0006986 // response to unfolded protein // inferred from electronic annotation /// 0008284 // positive regulation of cell proliferation // inferred from direct assay /// 0030307 // positive regulation of cell growth // inferred from direct assay /// 0030433 // ER-associated ubiquitin-dependent protein catabolic process // inferred from mutant phenotype /// 0030968 // endoplasmic reticulum unfolded protein response // inferred from direct assay /// 0030970 // retrograde protein transport, ER to cytosol // inferred from mutant phenotype",0005769 // early endosome // inferred from electronic annotation /// 0005770 // late endosome // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0030176 // integral component of endoplasmic reticulum membrane // inferred from direct assay,-0.141169887,0.002297174,TRUE
204240_s_at,SMC2,10592,ENSG00000136824 /// OTTHUMG00000020401,structural maintenance of chromosomes 2,0000278 // mitotic cell cycle // traceable author statement /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007062 // sister chromatid cohesion // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007076 // mitotic chromosome condensation // inferred from direct assay /// 0010032 // meiotic chromosome condensation // inferred from electronic annotation /// 0030261 // chromosome condensation // inferred from electronic annotation /// 0045132 // meiotic chromosome segregation // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation /// 0051383 // kinetochore organization // inferred from electronic annotation,0000228 // nuclear chromosome // inferred from direct assay /// 0000793 // condensed chromosome // inferred from direct assay /// 0000796 // condensin complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay,-0.259790058,0.002329693,TRUE
213951_s_at,PSMC3IP,29893,ENSG00000131470 /// OTTHUMG00000180247,PSMC3 interacting protein,"0006310 // DNA recombination // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007126 // meiotic nuclear division // inferred from electronic annotation /// 0007165 // signal transduction // inferred from electronic annotation /// 0045892 // negative regulation of transcription, DNA-templated // inferred from electronic annotation /// 2001141 // regulation of RNA biosynthetic process // inferred from mutant phenotype",0005634 // nucleus // inferred from electronic annotation,-0.137991403,0.002359425,TRUE
204924_at,TLR2,7097,ENSG00000137462 /// OTTHUMG00000161525,toll-like receptor 2,0001666 // response to hypoxia // inferred from electronic annotation /// 0002224 // toll-like receptor signaling pathway // traceable author statement /// 0002237 // response to molecule of bacterial origin // inferred from electronic annotation /// 0002238 // response to molecule of fungal origin // inferred from electronic annotation /// 0002282 // microglial cell activation involved in immune response // inferred from electronic annotation /// 0002376 // immune system process // inferred from electronic annotation /// 0002687 // positive regulation of leukocyte migration // inferred from electronic annotation /// 0002752 // cell surface pattern recognition receptor signaling pathway // inferred from electronic annotation /// 0002755 // MyD88-dependent toll-like receptor signaling pathway // traceable author statement /// 0006691 // leukotriene metabolic process // inferred from electronic annotation /// 0006915 // apoptotic process // traceable author statement /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0007165 // signal transduction // traceable author statement /// 0007252 // I-kappaB phosphorylation // inferred from direct assay /// 0008285 // negative regulation of cell proliferation // inferred from electronic annotation /// 0009617 // response to bacterium // inferred from electronic annotation /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0030177 // positive regulation of Wnt signaling pathway // inferred from mutant phenotype /// 0031663 // lipopolysaccharide-mediated signaling pathway // traceable author statement /// 0032289 // central nervous system myelin formation // inferred from electronic annotation /// 0032493 // response to bacterial lipoprotein // inferred from electronic annotation /// 0032494 // response to peptidoglycan // inferred from electronic annotation /// 0032496 // response to lipopolysaccharide // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032695 // negative regulation of interleukin-12 production // inferred from electronic annotation /// 0032700 // negative regulation of interleukin-17 production // inferred from electronic annotation /// 0032722 // positive regulation of chemokine production // inferred from direct assay /// 0032728 // positive regulation of interferon-beta production // inferred from sequence or structural similarity /// 0032733 // positive regulation of interleukin-10 production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from sequence or structural similarity /// 0032741 // positive regulation of interleukin-18 production // inferred from sequence or structural similarity /// 0032755 // positive regulation of interleukin-6 production // inferred from direct assay /// 0032757 // positive regulation of interleukin-8 production // inferred from direct assay /// 0032760 // positive regulation of tumor necrosis factor production // inferred from sequence or structural similarity /// 0032868 // response to insulin // inferred from electronic annotation /// 0034123 // positive regulation of toll-like receptor signaling pathway // inferred from direct assay /// 0034134 // toll-like receptor 2 signaling pathway // traceable author statement /// 0034142 // toll-like receptor 4 signaling pathway // traceable author statement /// 0038123 // toll-like receptor TLR1:TLR2 signaling pathway // traceable author statement /// 0038124 // toll-like receptor TLR6:TLR2 signaling pathway // traceable author statement /// 0042346 // positive regulation of NF-kappaB import into nucleus // inferred from direct assay /// 0042495 // detection of triacyl bacterial lipopeptide // inferred from direct assay /// 0042496 // detection of diacyl bacterial lipopeptide // inferred from direct assay /// 0042535 // positive regulation of tumor necrosis factor biosynthetic process // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042892 // chloramphenicol transport // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045087 // innate immune response // traceable author statement /// 0045429 // positive regulation of nitric oxide biosynthetic process // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from sequence or structural similarity /// 0046209 // nitric oxide metabolic process // inferred from electronic annotation /// 0048714 // positive regulation of oligodendrocyte differentiation // inferred from electronic annotation /// 0050707 // regulation of cytokine secretion // inferred from electronic annotation /// 0050715 // positive regulation of cytokine secretion // inferred from electronic annotation /// 0050729 // positive regulation of inflammatory response // inferred by curator /// 0050830 // defense response to Gram-positive bacterium // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0051770 // positive regulation of nitric-oxide synthase biosynthetic process // inferred from sequence or structural similarity /// 0052033 // pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response // inferred from electronic annotation /// 0052063 // induction by symbiont of defense-related host nitric oxide production // inferred from electronic annotation /// 0060907 // positive regulation of macrophage cytokine production // inferred from electronic annotation /// 0070542 // response to fatty acid // inferred from electronic annotation /// 0071221 // cellular response to bacterial lipopeptide // traceable author statement /// 0071223 // cellular response to lipoteichoic acid // inferred from direct assay /// 0071224 // cellular response to peptidoglycan // inferred from electronic annotation /// 0071726 // cellular response to diacyl bacterial lipopeptide // inferred from direct assay /// 0071727 // cellular response to triacyl bacterial lipopeptide // inferred from direct assay,0005737 // cytoplasm // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // traceable author statement /// 0009897 // external side of plasma membrane // inferred from electronic annotation /// 0009986 // cell surface // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0035354 // Toll-like receptor 1-Toll-like receptor 2 protein complex // inferred from direct assay /// 0035355 // Toll-like receptor 2-Toll-like receptor 6 protein complex // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from electronic annotation,-0.239503314,0.002366685,TRUE
201473_at,JUNB,3726,ENSG00000171223 /// OTTHUMG00000180373,jun B proto-oncogene,"0001570 // vasculogenesis // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // traceable author statement /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0007179 // transforming growth factor beta receptor signaling pathway // traceable author statement /// 0007565 // female pregnancy // inferred from electronic annotation /// 0009416 // response to light stimulus // inferred from electronic annotation /// 0009612 // response to mechanical stimulus // inferred from electronic annotation /// 0009987 // cellular process // inferred from electronic annotation /// 0010467 // gene expression // traceable author statement /// 0014070 // response to organic cyclic compound // inferred from electronic annotation /// 0030316 // osteoclast differentiation // inferred from electronic annotation /// 0032570 // response to progesterone // inferred from electronic annotation /// 0032870 // cellular response to hormone stimulus // inferred from electronic annotation /// 0033687 // osteoblast proliferation // inferred from electronic annotation /// 0034097 // response to cytokine // inferred from electronic annotation /// 0042493 // response to drug // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0046697 // decidualization // inferred from electronic annotation /// 0051412 // response to corticosterone // inferred from electronic annotation /// 0051591 // response to cAMP // inferred from electronic annotation /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 0060136 // embryonic process involved in female pregnancy // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0071277 // cellular response to calcium ion // inferred from electronic annotation",0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay,0.236068172,0.002368158,TRUE
202340_x_at,NR4A1,3164,ENSG00000123358 /// OTTHUMG00000150393,"nuclear receptor subfamily 4, group A, member 1","0001938 // positive regulation of endothelial cell proliferation // inferred from mutant phenotype /// 0002042 // cell migration involved in sprouting angiogenesis // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007173 // epidermal growth factor receptor signaling pathway // traceable author statement /// 0008543 // fibroblast growth factor receptor signaling pathway // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0030522 // intracellular receptor signaling pathway // inferred from electronic annotation /// 0030522 // intracellular receptor signaling pathway // traceable author statement /// 0035767 // endothelial cell chemotaxis // inferred from mutant phenotype /// 0035914 // skeletal muscle cell differentiation // inferred from electronic annotation /// 0035924 // cellular response to vascular endothelial growth factor stimulus // inferred from mutant phenotype /// 0038095 // Fc-epsilon receptor signaling pathway // traceable author statement /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043154 // negative regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0043401 // steroid hormone mediated signaling pathway // inferred from electronic annotation /// 0044344 // cellular response to fibroblast growth factor stimulus // inferred from mutant phenotype /// 0045087 // innate immune response // traceable author statement /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0048015 // phosphatidylinositol-mediated signaling // traceable author statement /// 0071310 // cellular response to organic substance // inferred from electronic annotation",0005634 // nucleus // inferred from sequence or structural similarity /// 0005654 // nucleoplasm // traceable author statement /// 0005667 // transcription factor complex // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation,0.219373851,0.002388043,TRUE
208795_s_at,MCM7,4176,ENSG00000166508 /// OTTHUMG00000154671,minichromosome maintenance complex component 7,0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from mutant phenotype /// 0007049 // cell cycle // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation /// 0032508 // DNA duplex unwinding // inferred from electronic annotation /// 0042325 // regulation of phosphorylation // inferred from mutant phenotype /// 0042493 // response to drug // inferred from electronic annotation /// 0071310 // cellular response to organic substance // inferred from electronic annotation /// 0071364 // cellular response to epidermal growth factor stimulus // inferred from electronic annotation,0000785 // chromatin // traceable author statement /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay /// 0042555 // MCM complex // inferred from mutant phenotype,-0.171695224,0.00243851,TRUE
218057_x_at,EMC8,10328,ENSG00000131148 /// OTTHUMG00000137647,ER membrane protein complex subunit 8,---,0005634 // nucleus // traceable author statement /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0072546 // ER membrane protein complex // inferred from direct assay,-0.165312144,0.002445933,TRUE
221561_at,SOAT1,6646,ENSG00000057252 /// OTTHUMG00000035253,sterol O-acyltransferase 1,0006629 // lipid metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from direct assay /// 0008203 // cholesterol metabolic process // inferred from mutant phenotype /// 0010742 // macrophage derived foam cell differentiation // inferred by curator /// 0010742 // macrophage derived foam cell differentiation // inferred from mutant phenotype /// 0010742 // macrophage derived foam cell differentiation // non-traceable author statement /// 0010878 // cholesterol storage // inferred from mutant phenotype /// 0033344 // cholesterol efflux // inferred from mutant phenotype /// 0034379 // very-low-density lipoprotein particle assembly // inferred from mutant phenotype /// 0034435 // cholesterol esterification // inferred from direct assay /// 0034435 // cholesterol esterification // inferred from mutant phenotype /// 0042632 // cholesterol homeostasis // traceable author statement /// 0042986 // positive regulation of amyloid precursor protein biosynthetic process // inferred from mutant phenotype,0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay /// 0016021 // integral component of membrane // inferred from electronic annotation,-0.193588434,0.002504659,TRUE
204057_at,IRF8,3394,ENSG00000140968 /// OTTHUMG00000137648,interferon regulatory factor 8,"0000122 // negative regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006909 // phagocytosis // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0009617 // response to bacterium // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030099 // myeloid cell differentiation // inferred from electronic annotation /// 0032729 // positive regulation of interferon-gamma production // inferred from electronic annotation /// 0032735 // positive regulation of interleukin-12 production // inferred from electronic annotation /// 0042742 // defense response to bacterium // inferred from electronic annotation /// 0042832 // defense response to protozoan // inferred from electronic annotation /// 0044130 // negative regulation of growth of symbiont in host // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0060261 // positive regulation of transcription initiation from RNA polymerase II promoter // inferred from electronic annotation /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060337 // type I interferon signaling pathway // traceable author statement /// 0071222 // cellular response to lipopolysaccharide // inferred from electronic annotation",0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement,-0.18861344,0.002494055,TRUE
217933_s_at,LAP3,51056,ENSG00000002549 /// OTTHUMG00000048214,leucine aminopeptidase 3,0006508 // proteolysis // non-traceable author statement /// 0019538 // protein metabolic process // inferred from electronic annotation,0005622 // intracellular // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from electronic annotation /// 0005802 // trans-Golgi network // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay,-0.23986137,0.002545929,TRUE
215023_s_at,PEX1,5189,ENSG00000127980 /// OTTHUMG00000023926,peroxisomal biogenesis factor 1,0006200 // ATP catabolic process // inferred from electronic annotation /// 0006200 // ATP catabolic process // inferred from mutant phenotype /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006625 // protein targeting to peroxisome // inferred from mutant phenotype /// 0006810 // transport // inferred from electronic annotation /// 0007031 // peroxisome organization // inferred from mutant phenotype /// 0008152 // metabolic process // inferred from electronic annotation /// 0015031 // protein transport // inferred from electronic annotation /// 0016558 // protein import into peroxisome matrix // inferred from mutant phenotype /// 0060152 // microtubule-based peroxisome localization // inferred from mutant phenotype,0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005777 // peroxisome // inferred from direct assay /// 0005778 // peroxisomal membrane // inferred from direct assay /// 0005829 // cytosol // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay,-0.13204764,0.002582956,TRUE
205286_at,TFAP2C,7022,ENSG00000087510 /// OTTHUMG00000032805,transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma),"0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001829 // trophectodermal cell differentiation // inferred from electronic annotation /// 0001942 // hair follicle development // inferred from electronic annotation /// 0003334 // keratinocyte development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // traceable author statement /// 0006366 // transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0007267 // cell-cell signaling // traceable author statement /// 0008584 // male gonad development // inferred from expression pattern /// 0019827 // stem cell maintenance // inferred from electronic annotation /// 0021877 // forebrain neuron fate commitment // inferred from electronic annotation /// 0021987 // cerebral cortex development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030718 // germ-line stem cell maintenance // inferred from electronic annotation /// 0035019 // somatic stem cell maintenance // inferred from electronic annotation /// 0043588 // skin development // inferred from electronic annotation /// 0045682 // regulation of epidermis development // inferred from electronic annotation /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048733 // sebaceous gland development // inferred from electronic annotation /// 0060598 // dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis // inferred from electronic annotation /// 0060750 // epithelial cell proliferation involved in mammary gland duct elongation // inferred from electronic annotation",0005634 // nucleus // inferred from electronic annotation,0.309067902,0.002643746,TRUE
209680_s_at,KIFC1,3833,ENSG00000204197 /// ENSG00000233450 /// ENSG00000237649 /// OTTHUMG00000013689 /// OTTHUMG00000031209 /// OTTHUMG00000140157,kinesin family member C1,0000070 // mitotic sister chromatid segregation // non-traceable author statement /// 0007018 // microtubule-based movement // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007596 // blood coagulation // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation,0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from electronic annotation /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from electronic annotation /// 0005874 // microtubule // inferred from electronic annotation /// 0005875 // microtubule associated complex // non-traceable author statement /// 0016020 // membrane // inferred from direct assay,-0.17862986,0.002645897,TRUE
209479_at,CCDC28A,25901,ENSG00000024862 /// OTTHUMG00000015683,coiled-coil domain containing 28A,---,---,-0.160850439,0.002716867,TRUE
206715_at,TFEC,22797,ENSG00000105967 /// OTTHUMG00000023518,transcription factor EC,"0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0034605 // cellular response to heat // inferred from electronic annotation",0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay,-0.248246464,0.002732411,TRUE
202900_s_at,NUP88,4927,ENSG00000108559 /// OTTHUMG00000099453,nucleoporin 88kDa,0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0051028 // mRNA transport // inferred from electronic annotation /// 0055085 // transmembrane transport // traceable author statement,0005634 // nucleus // inferred from direct assay /// 0005643 // nuclear pore // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement,-0.18305811,0.002744159,TRUE
218156_s_at,TSR1,55720,ENSG00000167721 /// OTTHUMG00000177636,"TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)",0042254 // ribosome biogenesis // inferred from electronic annotation /// 0042255 // ribosome assembly // inferred from sequence or structural similarity,0005634 // nucleus // inferred from electronic annotation /// 0005730 // nucleolus // inferred from sequence or structural similarity,-0.151925155,0.002815804,TRUE
203706_s_at,FZD7,8324,ENSG00000155760 /// OTTHUMG00000132841,frizzled class receptor 7,"0001944 // vasculature development // not recorded /// 0006355 // regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0007165 // signal transduction // inferred from electronic annotation /// 0007166 // cell surface receptor signaling pathway // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007199 // G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger // not recorded /// 0007223 // Wnt signaling pathway, calcium modulating pathway // not recorded /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007409 // axonogenesis // not recorded /// 0007420 // brain development // not recorded /// 0008406 // gonad development // not recorded /// 0010812 // negative regulation of cell-substrate adhesion // inferred from mutant phenotype /// 0014834 // satellite cell maintenance involved in skeletal muscle regeneration // inferred from electronic annotation /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0019827 // stem cell maintenance // inferred from mutant phenotype /// 0030182 // neuron differentiation // inferred from sequence or structural similarity /// 0033077 // T cell differentiation in thymus // inferred from electronic annotation /// 0034446 // substrate adhesion-dependent cell spreading // inferred from electronic annotation /// 0035412 // regulation of catenin import into nucleus // inferred from mutant phenotype /// 0035567 // non-canonical Wnt signaling pathway // inferred from electronic annotation /// 0038031 // non-canonical Wnt signaling pathway via JNK cascade // inferred from mutant phenotype /// 0042327 // positive regulation of phosphorylation // inferred from direct assay /// 0042666 // negative regulation of ectodermal cell fate specification // inferred from mutant phenotype /// 0045893 // positive regulation of transcription, DNA-templated // inferred from direct assay /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0046330 // positive regulation of JNK cascade // inferred by curator /// 0048103 // somatic stem cell division // inferred from electronic annotation /// 0060054 // positive regulation of epithelial cell proliferation involved in wound healing // inferred from mutant phenotype /// 0060070 // canonical Wnt signaling pathway // inferred from direct assay /// 0060070 // canonical Wnt signaling pathway // inferred from mutant phenotype /// 0060231 // mesenchymal to epithelial transition // inferred from mutant phenotype /// 0071300 // cellular response to retinoic acid // inferred from sequence or structural similarity",0005737 // cytoplasm // not recorded /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // traceable author statement /// 0032589 // neuron projection membrane // not recorded /// 0045177 // apical part of cell // not recorded,0.282712851,0.002875251,TRUE
209928_s_at,MSC,9242,ENSG00000178860 /// OTTHUMG00000164489,musculin,"0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0014707 // branchiomeric skeletal muscle development // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060539 // diaphragm development // inferred from electronic annotation",0005634 // nucleus // inferred from electronic annotation,0.05322203,0.002930744,TRUE
214032_at,ZAP70,7535,ENSG00000115085 /// OTTHUMG00000153060,zeta-chain (TCR) associated protein kinase 70kDa,0002250 // adaptive immune response // traceable author statement /// 0002376 // immune system process // inferred from electronic annotation /// 0006468 // protein phosphorylation // inferred from direct assay /// 0006468 // protein phosphorylation // non-traceable author statement /// 0006955 // immune response // inferred from direct assay /// 0016310 // phosphorylation // inferred from electronic annotation /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from direct assay /// 0018108 // peptidyl-tyrosine phosphorylation // inferred from mutant phenotype /// 0030217 // T cell differentiation // non-traceable author statement /// 0035556 // intracellular signal transduction // non-traceable author statement /// 0042110 // T cell activation // traceable author statement /// 0042113 // B cell activation // traceable author statement /// 0043366 // beta selection // inferred from electronic annotation /// 0045059 // positive thymic T cell selection // inferred from direct assay /// 0045060 // negative thymic T cell selection // inferred from electronic annotation /// 0045061 // thymic T cell selection // inferred from electronic annotation /// 0045582 // positive regulation of T cell differentiation // inferred from direct assay /// 0046638 // positive regulation of alpha-beta T cell differentiation // inferred from electronic annotation /// 0046641 // positive regulation of alpha-beta T cell proliferation // inferred from electronic annotation /// 0046777 // protein autophosphorylation // inferred from electronic annotation /// 0050850 // positive regulation of calcium-mediated signaling // inferred from electronic annotation /// 0050852 // T cell receptor signaling pathway // traceable author statement /// 0070489 // T cell aggregation // traceable author statement /// 0072678 // T cell migration // traceable author statement,0001772 // immunological synapse // inferred from electronic annotation /// 0005737 // cytoplasm // traceable author statement /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0005886 // plasma membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0042101 // T cell receptor complex // inferred from direct assay /// 0045121 // membrane raft // inferred from direct assay,-0.05343478,0.00293571,TRUE
211160_x_at,ACTN1,87,---,"actinin, alpha 1",0002576 // platelet degranulation // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0030168 // platelet activation // traceable author statement /// 0030198 // extracellular matrix organization // traceable author statement /// 0034329 // cell junction assembly // traceable author statement /// 0042981 // regulation of apoptotic process // non-traceable author statement /// 0048041 // focal adhesion assembly // inferred from mutant phenotype /// 0051017 // actin filament bundle assembly // inferred from electronic annotation /// 0051271 // negative regulation of cellular component movement // inferred from mutant phenotype /// 0051764 // actin crosslink formation // inferred from electronic annotation,0001726 // ruffle // inferred from electronic annotation /// 0005576 // extracellular region // traceable author statement /// 0005615 // extracellular space // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from electronic annotation /// 0005916 // fascia adherens // inferred from electronic annotation /// 0005925 // focal adhesion // inferred from mutant phenotype /// 0016020 // membrane // inferred from electronic annotation /// 0030018 // Z disc // inferred from electronic annotation /// 0030054 // cell junction // inferred from electronic annotation /// 0031093 // platelet alpha granule lumen // traceable author statement /// 0031143 // pseudopodium // traceable author statement /// 0042995 // cell projection // inferred from direct assay /// 0043197 // dendritic spine // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.140529181,0.002940166,TRUE
209079_x_at,PCDHGA1 /// PCDHGA10 /// PCDHGA11 /// PCDHGA12 /// PCDHGA2 /// PCDHGA3 /// PCDHGA4 /// PCDHGA5 /// PCDHGA6 /// PCDHGA7 /// PCDHGA8 /// PCDHGA9 /// PCDHGB1 /// PCDHGB2 /// PCDHGB3 /// PCDHGB4 /// PCDHGB5 /// PCDHGB6 /// PCDHGB7 /// PCDHGC3 /// PCDHGC4 /// PCDHGC5,5098 /// 8641 /// 9708 /// 26025 /// 56097 /// 56098 /// 56099 /// 56100 /// 56101 /// 56102 /// 56103 /// 56104 /// 56105 /// 56106 /// 56107 /// 56108 /// 56109 /// 56110 /// 56111 /// 56112 /// 56113 /// 56114,ENSG00000081853 /// ENSG00000204956 /// ENSG00000240184 /// ENSG00000240764 /// ENSG00000242419 /// ENSG00000253159 /// ENSG00000253305 /// ENSG00000253485 /// ENSG00000253537 /// ENSG00000253731 /// ENSG00000253767 /// ENSG00000253846 /// ENSG00000253873 /// ENSG00000253910 /// ENSG00000253953 /// ENSG00000254122 /// ENSG00000254221 /// ENSG00000254245 /// ENSG00000261934 /// ENSG00000262209 /// ENSG00000262576 /// OTTHUMG00000129611 /// OTTHUMG00000129613 /// OTTHUMG00000129624 /// OTTHUMG00000129625 /// OTTHUMG00000163678 /// OTTHUMG00000163679 /// OTTHUMG00000163680 /// OTTHUMG00000163681 /// OTTHUMG00000163682 /// OTTHUMG00000163683 /// OTTHUMG00000163684 /// OTTHUMG00000163685 /// OTTHUMG00000163686 /// OTTHUMG00000163687 /// OTTHUMG00000163688 /// OTTHUMG00000164053 /// OTTHUMG00000164054 /// OTTHUMG00000164055 /// OTTHUMG00000177471 /// OTTHUMG00000177473 /// OTTHUMG00000177593,"protocadherin gamma subfamily A, 1 /// protocadherin gamma subfamily A, 10 /// protocadherin gamma subfamily A, 11 /// protocadherin gamma subfamily A, 12 /// protocadherin gamma subfamily A, 2 /// protocadherin gamma subfamily A, 3 /// protocadherin gamma subfamily A, 4 /// protocadherin gamma subfamily A, 5 /// protocadherin gamma subfamily A, 6 /// protocadherin gamma subfamily A, 7 /// protocadherin gamma subfamily A, 8 /// protocadherin gamma subfamily A, 9 /// protocadherin gamma subfamily B, 1 /// protocadherin gamma subfamily B, 2 /// protocadherin gamma subfamily B, 3 /// protocadherin gamma subfamily B, 4 /// protocadherin gamma subfamily B, 5 /// protocadherin gamma subfamily B, 6 /// protocadherin gamma subfamily B, 7 /// protocadherin gamma subfamily C, 3 /// protocadherin gamma subfamily C, 4 /// protocadherin gamma subfamily C, 5",0007155 // cell adhesion // traceable author statement /// 0007156 // homophilic cell adhesion // inferred from electronic annotation /// 0007283 // spermatogenesis // inferred from electronic annotation /// 0016339 // calcium-dependent cell-cell adhesion // non-traceable author statement,0005886 // plasma membrane // inferred from electronic annotation /// 0016020 // membrane // non-traceable author statement /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.209569567,0.002949934,TRUE
213136_at,PTPN2,5771,ENSG00000175354 /// OTTHUMG00000131702,"protein tyrosine phosphatase, non-receptor type 2",0006470 // protein dephosphorylation // inferred from electronic annotation /// 0008285 // negative regulation of cell proliferation // inferred from mutant phenotype /// 0008286 // insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0010804 // negative regulation of tumor necrosis factor-mediated signaling pathway // inferred from sequence or structural similarity /// 0010888 // negative regulation of lipid storage // inferred from sequence or structural similarity /// 0016311 // dephosphorylation // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030217 // T cell differentiation // inferred from sequence or structural similarity /// 0030218 // erythrocyte differentiation // inferred from sequence or structural similarity /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from direct assay /// 0035335 // peptidyl-tyrosine dephosphorylation // inferred from mutant phenotype /// 0042059 // negative regulation of epidermal growth factor receptor signaling pathway // inferred from mutant phenotype /// 0042512 // negative regulation of tyrosine phosphorylation of Stat1 protein // inferred from direct assay /// 0042512 // negative regulation of tyrosine phosphorylation of Stat1 protein // inferred from mutant phenotype /// 0042518 // negative regulation of tyrosine phosphorylation of Stat3 protein // inferred from direct assay /// 0042524 // negative regulation of tyrosine phosphorylation of Stat5 protein // inferred from sequence or structural similarity /// 0042527 // negative regulation of tyrosine phosphorylation of Stat6 protein // inferred from electronic annotation /// 0042527 // negative regulation of tyrosine phosphorylation of Stat6 protein // inferred from mutant phenotype /// 0042593 // glucose homeostasis // inferred from sequence or structural similarity /// 0045650 // negative regulation of macrophage differentiation // inferred from sequence or structural similarity /// 0045722 // positive regulation of gluconeogenesis // inferred from sequence or structural similarity /// 0046627 // negative regulation of insulin receptor signaling pathway // inferred from sequence or structural similarity /// 0050728 // negative regulation of inflammatory response // inferred from sequence or structural similarity /// 0050860 // negative regulation of T cell receptor signaling pathway // inferred from sequence or structural similarity /// 0050922 // negative regulation of chemotaxis // inferred from sequence or structural similarity /// 0060333 // interferon-gamma-mediated signaling pathway // traceable author statement /// 0060334 // regulation of interferon-gamma-mediated signaling pathway // traceable author statement /// 0060336 // negative regulation of interferon-gamma-mediated signaling pathway // inferred from sequence or structural similarity /// 0060339 // negative regulation of type I interferon-mediated signaling pathway // inferred from mutant phenotype /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from electronic annotation /// 0070104 // negative regulation of interleukin-6-mediated signaling pathway // inferred from mutant phenotype /// 0070373 // negative regulation of ERK1 and ERK2 cascade // inferred from sequence or structural similarity /// 1902202 // regulation of hepatocyte growth factor receptor signaling pathway // inferred from mutant phenotype /// 1902206 // negative regulation of interleukin-2-mediated signaling pathway // inferred from mutant phenotype /// 1902212 // negative regulation of prolactin signaling pathway // inferred from sequence or structural similarity /// 1902215 // negative regulation of interleukin-4-mediated signaling pathway // inferred from electronic annotation /// 1902215 // negative regulation of interleukin-4-mediated signaling pathway // inferred from mutant phenotype /// 1902227 // negative regulation of macrophage colony-stimulating factor signaling pathway // inferred from sequence or structural similarity /// 1902233 // negative regulation of positive thymic T cell selection // inferred from sequence or structural similarity /// 2000587 // negative regulation of platelet-derived growth factor receptor-beta signaling pathway // inferred from sequence or structural similarity,0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005783 // endoplasmic reticulum // inferred from direct assay /// 0005793 // endoplasmic reticulum-Golgi intermediate compartment // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation,-0.132778742,0.002976096,TRUE
216668_at,PABPC1P1 /// PABPC1P1,---,ENSG00000231707 /// OTTHUMG00000160579,"--- /// poly(A) binding protein, cytoplasmic 1 pseudogene 1",---,---,0.064347007,0.00304867,TRUE
219950_s_at,TIAM2,26230,---,T-cell lymphoma invasion and metastasis 2,0007165 // signal transduction // inferred from electronic annotation /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0044255 // cellular lipid metabolic process // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement,0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0030027 // lamellipodium // inferred from electronic annotation /// 0030175 // filopodium // inferred from electronic annotation /// 0030426 // growth cone // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay,-0.04757589,0.003126907,TRUE
204127_at,RFC3,5983,ENSG00000133119 /// OTTHUMG00000016715,"replication factor C (activator 1) 3, 38kDa","0000278 // mitotic cell cycle // traceable author statement /// 0000722 // telomere maintenance via recombination // traceable author statement /// 0000723 // telomere maintenance // traceable author statement /// 0000731 // DNA synthesis involved in DNA repair // traceable author statement /// 0006200 // ATP catabolic process // inferred from direct assay /// 0006260 // DNA replication // inferred from direct assay /// 0006260 // DNA replication // traceable author statement /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006283 // transcription-coupled nucleotide-excision repair // traceable author statement /// 0006289 // nucleotide-excision repair // traceable author statement /// 0006297 // nucleotide-excision repair, DNA gap filling // traceable author statement /// 0032201 // telomere maintenance via semi-conservative replication // traceable author statement /// 0046683 // response to organophosphorus // inferred from expression pattern",0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005663 // DNA replication factor C complex // inferred from direct assay /// 0005663 // DNA replication factor C complex // traceable author statement,-0.221461638,0.003129763,TRUE
210922_at,CTB-102L5.7,---,ENSG00000269653 /// OTTHUMG00000182401,---,---,---,0.047011701,0.003153306,TRUE
221436_s_at,CDCA3,83461,ENSG00000111665 /// OTTHUMG00000169014,cell division cycle associated 3,0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation,0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from electronic annotation,-0.277809595,0.003173978,TRUE
206078_at,KALRN,8997,ENSG00000160145 /// OTTHUMG00000125545,"kalirin, RhoGEF kinase",0006468 // protein phosphorylation // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007264 // small GTPase mediated signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from sequence or structural similarity /// 0016192 // vesicle-mediated transport // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0032319 // regulation of Rho GTPase activity // inferred from electronic annotation /// 0032321 // positive regulation of Rho GTPase activity // inferred from electronic annotation /// 0035023 // regulation of Rho protein signal transduction // inferred from electronic annotation /// 0035556 // intracellular signal transduction // inferred from sequence or structural similarity /// 0043065 // positive regulation of apoptotic process // traceable author statement /// 0043087 // regulation of GTPase activity // traceable author statement /// 0043547 // positive regulation of GTPase activity // inferred from electronic annotation /// 0043547 // positive regulation of GTPase activity // traceable author statement /// 0048011 // neurotrophin TRK receptor signaling pathway // traceable author statement /// 0051056 // regulation of small GTPase mediated signal transduction // traceable author statement /// 0097190 // apoptotic signaling pathway // traceable author statement,0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0015629 // actin cytoskeleton // traceable author statement /// 0070062 // extracellular vesicular exosome // inferred from direct assay,-0.076919315,0.003240526,TRUE
219940_s_at,PCID2,55795,ENSG00000126226 /// OTTHUMG00000017385,PCI domain containing 2,"0043066 // negative regulation of apoptotic process // inferred from mutant phenotype /// 0043488 // regulation of mRNA stability // inferred from mutant phenotype /// 0045579 // positive regulation of B cell differentiation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from mutant phenotype /// 0048536 // spleen development // inferred from sequence or structural similarity /// 0090267 // positive regulation of mitotic cell cycle spindle assembly checkpoint // inferred from mutant phenotype /// 2000117 // negative regulation of cysteine-type endopeptidase activity // inferred from mutant phenotype",---,-0.172061934,0.003323046,TRUE
213656_s_at,KLC1,3831,ENSG00000126214 /// OTTHUMG00000169227,kinesin light chain 1,0006886 // intracellular protein transport // inferred from electronic annotation /// 0007018 // microtubule-based movement // traceable author statement /// 0007596 // blood coagulation // traceable author statement /// 0008088 // axon cargo transport // inferred from electronic annotation /// 0008152 // metabolic process // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0016032 // viral process // inferred from electronic annotation /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019886 // antigen processing and presentation of exogenous peptide antigen via MHC class II // traceable author statement /// 0035418 // protein localization to synapse // inferred from electronic annotation /// 0035617 // stress granule disassembly // inferred from sequence or structural similarity,0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0005871 // kinesin complex // inferred from sequence or structural similarity /// 0005874 // microtubule // inferred from electronic annotation /// 0016020 // membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016023 // cytoplasmic membrane-bounded vesicle // inferred from electronic annotation /// 0030424 // axon // inferred from electronic annotation /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031410 // cytoplasmic vesicle // inferred from electronic annotation /// 0031982 // vesicle // inferred from electronic annotation /// 0035253 // ciliary rootlet // inferred from electronic annotation /// 0042995 // cell projection // inferred from electronic annotation /// 0043005 // neuron projection // inferred from electronic annotation /// 0043025 // neuronal cell body // inferred from electronic annotation /// 0043227 // membrane-bounded organelle // inferred from electronic annotation,0.140276603,0.003344118,TRUE
207574_s_at,GADD45B,4616,ENSG00000099860 /// OTTHUMG00000180434,"growth arrest and DNA-damage-inducible, beta",0000185 // activation of MAPKKK activity // inferred from direct assay /// 0000186 // activation of MAPKK activity // inferred from electronic annotation /// 0006469 // negative regulation of protein kinase activity // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006950 // response to stress // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from direct assay /// 0046330 // positive regulation of JNK cascade // inferred from direct assay /// 0051726 // regulation of cell cycle // inferred from electronic annotation /// 1900745 // positive regulation of p38MAPK cascade // inferred from direct assay,0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay,0.271071313,0.003349069,TRUE
202504_at,TRIM29,23650,ENSG00000137699 /// OTTHUMG00000140377,tripartite motif containing 29,0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 1900181 // negative regulation of protein localization to nucleus // inferred from electronic annotation,0005622 // intracellular // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from electronic annotation,0.482647549,0.003351677,TRUE
203755_at,BUB1B,701,ENSG00000156970 /// OTTHUMG00000129877,BUB1 mitotic checkpoint serine/threonine kinase B,"0000278 // mitotic cell cycle // traceable author statement /// 0006468 // protein phosphorylation // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0007049 // cell cycle // non-traceable author statement /// 0007051 // spindle organization // non-traceable author statement /// 0007067 // mitotic nuclear division // non-traceable author statement /// 0007091 // metaphase/anaphase transition of mitotic cell cycle // inferred from electronic annotation /// 0007093 // mitotic cell cycle checkpoint // traceable author statement /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0008283 // cell proliferation // traceable author statement /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0034501 // protein localization to kinetochore // inferred from physical interaction /// 0048015 // phosphatidylinositol-mediated signaling // non-traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0071459 // protein localization to chromosome, centromeric region // inferred from electronic annotation","0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000776 // kinetochore // inferred from direct assay /// 0000776 // kinetochore // non-traceable author statement /// 0000776 // kinetochore // traceable author statement /// 0000777 // condensed chromosome kinetochore // inferred from direct assay /// 0000778 // condensed nuclear chromosome kinetochore // inferred from electronic annotation /// 0000940 // condensed chromosome outer kinetochore // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005680 // anaphase-promoting complex // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005815 // microtubule organizing center // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0048471 // perinuclear region of cytoplasm // inferred from direct assay /// 0051233 // spindle midzone // non-traceable author statement",-0.197880297,0.003417414,TRUE
220204_s_at,BMP8A,353500,---,bone morphogenetic protein 8a,0001503 // ossification // inferred from electronic annotation /// 0002024 // diet induced thermogenesis // inferred from direct assay /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0040007 // growth // inferred from electronic annotation /// 0046676 // negative regulation of insulin secretion // inferred from direct assay /// 0051216 // cartilage development // inferred from electronic annotation /// 2000505 // regulation of energy homeostasis // inferred from direct assay,0005576 // extracellular region // inferred from electronic annotation /// 0005615 // extracellular space // inferred from electronic annotation,0.042593893,0.003455918,TRUE
205298_s_at,BTN2A2,10385,ENSG00000124508 /// OTTHUMG00000014452,"butyrophilin, subfamily 2, member A2",0031324 // negative regulation of cellular metabolic process // inferred from sequence or structural similarity /// 0046007 // negative regulation of activated T cell proliferation // inferred from sequence or structural similarity /// 0050710 // negative regulation of cytokine secretion // inferred from sequence or structural similarity,0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0070062 // extracellular vesicular exosome // inferred from direct assay,-0.150990794,0.003466637,TRUE
218575_at,ANAPC1 /// LOC730268,64682 /// 730268,ENSG00000153107 /// ENSG00000204745 /// OTTHUMG00000131277 /// OTTHUMG00000153253,anaphase promoting complex subunit 1 /// anaphase-promoting complex subunit 1-like,0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007094 // mitotic spindle assembly checkpoint // traceable author statement /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0031145 // anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process // traceable author statement /// 0051301 // cell division // inferred from electronic annotation /// 0051436 // negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051437 // positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0051439 // regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle // traceable author statement /// 0070979 // protein K11-linked ubiquitination // inferred from direct assay,0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement /// 0005680 // anaphase-promoting complex // inferred from direct assay /// 0005829 // cytosol // traceable author statement,-0.116960472,0.003476443,TRUE
49077_at,PPME1,51400,ENSG00000214517 /// OTTHUMG00000168115,protein phosphatase methylesterase 1,0006482 // protein demethylation // inferred from direct assay /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement,---,0.104064156,0.003503481,TRUE
206513_at,AIM2,9447,ENSG00000163568 /// OTTHUMG00000037183,absent in melanoma 2,"0002218 // activation of innate immune response // inferred from direct assay /// 0002230 // positive regulation of defense response to virus by host // inferred from sequence or structural similarity /// 0002376 // immune system process // inferred from electronic annotation /// 0006915 // apoptotic process // inferred from electronic annotation /// 0006954 // inflammatory response // inferred from electronic annotation /// 0006955 // immune response // traceable author statement /// 0032088 // negative regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0032461 // positive regulation of protein oligomerization // inferred from direct assay /// 0032731 // positive regulation of interleukin-1 beta production // inferred from direct assay /// 0033209 // tumor necrosis factor-mediated signaling pathway // inferred from direct assay /// 0035458 // cellular response to interferon-beta // inferred from electronic annotation /// 0035690 // cellular response to drug // inferred from direct assay /// 0035872 // nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway // traceable author statement /// 0045087 // innate immune response // traceable author statement /// 0050702 // interleukin-1 beta secretion // inferred from mutant phenotype /// 0050718 // positive regulation of interleukin-1 beta secretion // inferred from direct assay /// 0051092 // positive regulation of NF-kappaB transcription factor activity // inferred from direct assay /// 0070269 // pyroptosis // inferred from direct assay /// 2001056 // positive regulation of cysteine-type endopeptidase activity // inferred from direct assay",0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005739 // mitochondrion // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0097169 // AIM2 inflammasome complex // inferred from direct assay,-0.209336718,0.003528766,TRUE
202097_at,NUP153,9972,ENSG00000124789 /// OTTHUMG00000014312,nucleoporin 153kDa,0000278 // mitotic cell cycle // traceable author statement /// 0005975 // carbohydrate metabolic process // traceable author statement /// 0006810 // transport // inferred from electronic annotation /// 0006913 // nucleocytoplasmic transport // inferred from direct assay /// 0007077 // mitotic nuclear envelope disassembly // traceable author statement /// 0008645 // hexose transport // traceable author statement /// 0010827 // regulation of glucose transport // traceable author statement /// 0015031 // protein transport // inferred from electronic annotation /// 0015758 // glucose transport // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation /// 0019221 // cytokine-mediated signaling pathway // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046718 // viral entry into host cell // inferred from electronic annotation /// 0046832 // negative regulation of RNA export from nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0051292 // nuclear pore complex assembly // inferred from mutant phenotype /// 0055085 // transmembrane transport // traceable author statement /// 0075732 // viral penetration into host nucleus // inferred from electronic annotation,0005634 // nucleus // inferred from electronic annotation /// 0005643 // nuclear pore // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay /// 0034399 // nuclear periphery // inferred from direct assay /// 0042405 // nuclear inclusion body // inferred from direct assay /// 0044615 // nuclear pore nuclear basket // inferred from direct assay,-0.15986316,0.003523188,TRUE
202666_s_at,ACTL6A,86,ENSG00000136518 /// OTTHUMG00000157782,actin-like 6A,"0003407 // neural retina development // inferred from expression pattern /// 0006281 // DNA repair // inferred from electronic annotation /// 0006310 // DNA recombination // inferred from electronic annotation /// 0006325 // chromatin organization // traceable author statement /// 0006338 // chromatin remodeling // inferred by curator /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // non-traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007165 // signal transduction // traceable author statement /// 0007399 // nervous system development // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0040008 // regulation of growth // inferred from electronic annotation /// 0043044 // ATP-dependent chromatin remodeling // inferred from direct assay /// 0043967 // histone H4 acetylation // inferred from direct assay /// 0043968 // histone H2A acetylation // inferred from direct assay",0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016514 // SWI/SNF complex // inferred from direct assay /// 0031011 // Ino80 complex // inferred from direct assay /// 0035267 // NuA4 histone acetyltransferase complex // inferred from direct assay /// 0043234 // protein complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from direct assay /// 0071564 // npBAF complex // inferred from sequence or structural similarity,-0.164781926,0.003584483,TRUE
213007_at,FANCI,55215,ENSG00000140525 /// OTTHUMG00000132993,"Fanconi anemia, complementation group I",0006281 // DNA repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031398 // positive regulation of protein ubiquitination // inferred from direct assay,0005634 // nucleus // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from direct assay,-0.250896279,0.003603755,TRUE
210764_s_at,CYR61,3491,ENSG00000142871 /// OTTHUMG00000010577,"cysteine-rich, angiogenic inducer, 61","0001558 // regulation of cell growth // inferred from electronic annotation /// 0001649 // osteoblast differentiation // inferred from electronic annotation /// 0001934 // positive regulation of protein phosphorylation // inferred from direct assay /// 0002041 // intussusceptive angiogenesis // inferred from electronic annotation /// 0003181 // atrioventricular valve morphogenesis // inferred from electronic annotation /// 0003278 // apoptotic process involved in heart morphogenesis // inferred from electronic annotation /// 0003281 // ventricular septum development // inferred from electronic annotation /// 0006935 // chemotaxis // inferred from electronic annotation /// 0007155 // cell adhesion // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0009653 // anatomical structure morphogenesis // traceable author statement /// 0010518 // positive regulation of phospholipase activity // inferred from electronic annotation /// 0010811 // positive regulation of cell-substrate adhesion // inferred from electronic annotation /// 0016337 // single organismal cell-cell adhesion // inferred from electronic annotation /// 0030198 // extracellular matrix organization // inferred from electronic annotation /// 0030335 // positive regulation of cell migration // inferred from direct assay /// 0030513 // positive regulation of BMP signaling pathway // inferred from genetic interaction /// 0033690 // positive regulation of osteoblast proliferation // inferred from direct assay /// 0043065 // positive regulation of apoptotic process // inferred from electronic annotation /// 0043066 // negative regulation of apoptotic process // inferred from electronic annotation /// 0043280 // positive regulation of cysteine-type endopeptidase activity involved in apoptotic process // inferred from electronic annotation /// 0044319 // wound healing, spreading of cells // inferred from direct assay /// 0045597 // positive regulation of cell differentiation // inferred from electronic annotation /// 0045669 // positive regulation of osteoblast differentiation // inferred from direct assay /// 0045860 // positive regulation of protein kinase activity // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0060413 // atrial septum morphogenesis // inferred from electronic annotation /// 0060591 // chondroblast differentiation // inferred from electronic annotation /// 0060710 // chorio-allantoic fusion // inferred from electronic annotation /// 0060716 // labyrinthine layer blood vessel development // inferred from electronic annotation /// 0061036 // positive regulation of cartilage development // inferred from electronic annotation /// 0070372 // regulation of ERK1 and ERK2 cascade // inferred from direct assay /// 0072593 // reactive oxygen species metabolic process // inferred from electronic annotation /// 2000304 // positive regulation of ceramide biosynthetic process // inferred from electronic annotation",0005576 // extracellular region // inferred from electronic annotation,0.376007385,0.003661799,TRUE
218879_s_at,MTHFSD,64779,ENSG00000103248 /// OTTHUMG00000176480,methenyltetrahydrofolate synthetase domain containing,0009396 // folic acid-containing compound biosynthetic process // inferred from electronic annotation,---,-0.075396742,0.003685518,TRUE
219267_at,GLTP,51228,ENSG00000139433 /// OTTHUMG00000169278,glycolipid transfer protein,0006810 // transport // inferred from electronic annotation /// 0006869 // lipid transport // inferred from electronic annotation /// 0046836 // glycolipid transport // inferred from direct assay,0005737 // cytoplasm // inferred from electronic annotation /// 0016020 // membrane // inferred by curator /// 0070062 // extracellular vesicular exosome // inferred from direct assay,0.188448428,0.003689536,TRUE
212281_s_at,TMEM97,27346,ENSG00000109084 /// OTTHUMG00000132497,transmembrane protein 97,0001558 // regulation of cell growth // non-traceable author statement /// 0042632 // cholesterol homeostasis // inferred from direct assay,0005634 // nucleus // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005764 // lysosome // inferred from direct assay /// 0005783 // endoplasmic reticulum // inferred from electronic annotation /// 0005791 // rough endoplasmic reticulum // inferred from direct assay /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0031965 // nuclear membrane // inferred from direct assay,-0.199430121,0.00372666,TRUE
212461_at,AZIN1,51582,ENSG00000155096 /// OTTHUMG00000164766,antizyme inhibitor 1,0006521 // regulation of cellular amino acid metabolic process // traceable author statement /// 0006596 // polyamine biosynthetic process // inferred from electronic annotation /// 0034641 // cellular nitrogen compound metabolic process // traceable author statement /// 0042177 // negative regulation of protein catabolic process // inferred from direct assay /// 0043085 // positive regulation of catalytic activity // inferred from electronic annotation /// 0043086 // negative regulation of catalytic activity // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement,0005829 // cytosol // traceable author statement,0.162608712,0.003744525,TRUE
209418_s_at,THOC5,8563,ENSG00000100296 /// OTTHUMG00000151291,THO complex 5,"0006397 // mRNA processing // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0006810 // transport // inferred from electronic annotation /// 0008380 // RNA splicing // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0030224 // monocyte differentiation // inferred from direct assay /// 0032786 // positive regulation of DNA-templated transcription, elongation // inferred from mutant phenotype /// 0045650 // negative regulation of macrophage differentiation // inferred from electronic annotation /// 0046784 // viral mRNA export from host cell nucleus // inferred from direct assay /// 0051028 // mRNA transport // inferred from electronic annotation /// 0060215 // primitive hemopoiesis // inferred from sequence or structural similarity /// 2000002 // negative regulation of DNA damage checkpoint // inferred from mutant phenotype",0000346 // transcription export complex // inferred from direct assay /// 0000347 // THO complex // inferred from direct assay /// 0000445 // THO complex part of transcription export complex // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0016607 // nuclear speck // inferred from electronic annotation /// 0043231 // intracellular membrane-bounded organelle // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay,-0.180461758,0.003847687,TRUE
209141_at,UBE2G1,7326,ENSG00000132388 /// OTTHUMG00000177826,ubiquitin-conjugating enzyme E2G 1,0006511 // ubiquitin-dependent protein catabolic process // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0016567 // protein ubiquitination // inferred from electronic annotation /// 0070534 // protein K63-linked ubiquitination // inferred from direct assay /// 0070936 // protein K48-linked ubiquitination // inferred from direct assay,0070062 // extracellular vesicular exosome // inferred from direct assay,-0.141376503,0.003886213,TRUE
221520_s_at,CDCA8,55143,ENSG00000134690 /// OTTHUMG00000004320,cell division cycle associated 8,0000089 // mitotic metaphase // inferred from mutant phenotype /// 0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051276 // chromosome organization // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation,"0000775 // chromosome, centromeric region // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005819 // spindle // inferred from electronic annotation /// 0005825 // half bridge of spindle pole body // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // inferred from electronic annotation /// 0010369 // chromocenter // inferred from electronic annotation /// 0030496 // midbody // inferred from direct assay /// 0032133 // chromosome passenger complex // inferred from physical interaction /// 0043234 // protein complex // inferred from direct assay /// 0045171 // intercellular bridge // inferred from direct assay",-0.228443455,0.00391606,TRUE
201930_at,MCM6,4175,ENSG00000076003 /// OTTHUMG00000131739,minichromosome maintenance complex component 6,0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006260 // DNA replication // non-traceable author statement /// 0006260 // DNA replication // traceable author statement /// 0006268 // DNA unwinding involved in DNA replication // inferred from electronic annotation /// 0006270 // DNA replication initiation // inferred from electronic annotation /// 0006271 // DNA strand elongation involved in DNA replication // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0015979 // photosynthesis // inferred from electronic annotation /// 0015995 // chlorophyll biosynthetic process // inferred from electronic annotation,0005634 // nucleus // inferred from direct assay /// 0005634 // nucleus // non-traceable author statement /// 0005654 // nucleoplasm // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0042555 // MCM complex // inferred from direct assay,-0.176665818,0.00396191,TRUE
201431_s_at,DPYSL3,1809,ENSG00000113657 /// OTTHUMG00000163437,dihydropyrimidinase-like 3,0006208 // pyrimidine nucleobase catabolic process // inferred from electronic annotation /// 0007399 // nervous system development // inferred from electronic annotation /// 0007411 // axon guidance // traceable author statement /// 0008152 // metabolic process // inferred from electronic annotation /// 0010976 // positive regulation of neuron projection development // inferred from sequence or structural similarity /// 0010977 // negative regulation of neuron projection development // inferred from sequence or structural similarity /// 0030336 // negative regulation of cell migration // inferred from sequence or structural similarity /// 0048666 // neuron development // inferred from electronic annotation /// 0048678 // response to axon injury // inferred from sequence or structural similarity /// 0051017 // actin filament bundle assembly // inferred from sequence or structural similarity /// 0051260 // protein homooligomerization // inferred from sequence or structural similarity /// 0051491 // positive regulation of filopodium assembly // inferred from sequence or structural similarity /// 0051764 // actin crosslink formation // inferred from sequence or structural similarity /// 0071345 // cellular response to cytokine stimulus // inferred from sequence or structural similarity,0005615 // extracellular space // inferred from sequence or structural similarity /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // inferred from sequence or structural similarity /// 0005829 // cytosol // traceable author statement /// 0030027 // lamellipodium // inferred from sequence or structural similarity /// 0030426 // growth cone // inferred from sequence or structural similarity /// 0031941 // filamentous actin // inferred from sequence or structural similarity /// 0042995 // cell projection // inferred from electronic annotation /// 0044297 // cell body // inferred from sequence or structural similarity /// 0070382 // exocytic vesicle // inferred from sequence or structural similarity,0.324036975,0.003973255,TRUE
219371_s_at,KLF2,10365,ENSG00000127528 /// OTTHUMG00000182330,Kruppel-like factor 2,"0000902 // cell morphogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0032715 // negative regulation of interleukin-6 production // inferred from electronic annotation /// 0034101 // erythrocyte homeostasis // inferred from electronic annotation /// 0034616 // response to laminar fluid shear stress // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0036003 // positive regulation of transcription from RNA polymerase II promoter in response to stress // inferred from mutant phenotype /// 0043249 // erythrocyte maturation // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // inferred from electronic annotation /// 0045893 // positive regulation of transcription, DNA-templated // non-traceable author statement /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from genetic interaction /// 0051247 // positive regulation of protein metabolic process // inferred from genetic interaction /// 0060509 // Type I pneumocyte differentiation // inferred from electronic annotation /// 0070301 // cellular response to hydrogen peroxide // inferred from electronic annotation /// 0071347 // cellular response to interleukin-1 // inferred from electronic annotation /// 0071356 // cellular response to tumor necrosis factor // inferred from electronic annotation /// 0071407 // cellular response to organic cyclic compound // inferred from electronic annotation /// 0071409 // cellular response to cycloheximide // inferred from electronic annotation /// 0071499 // cellular response to laminar fluid shear stress // inferred from mutant phenotype /// 1901653 // cellular response to peptide // inferred from electronic annotation",0005634 // nucleus // inferred from electronic annotation,0.191226123,0.004000105,TRUE
201625_s_at,INSIG1,3638,ENSG00000186480 /// OTTHUMG00000151330,insulin induced gene 1,0006629 // lipid metabolic process // inferred from electronic annotation /// 0006641 // triglyceride metabolic process // inferred from electronic annotation /// 0006695 // cholesterol biosynthetic process // inferred from electronic annotation /// 0006991 // response to sterol depletion // inferred from electronic annotation /// 0008152 // metabolic process // traceable author statement /// 0008202 // steroid metabolic process // inferred from electronic annotation /// 0008203 // cholesterol metabolic process // inferred from electronic annotation /// 0008283 // cell proliferation // traceable author statement /// 0010894 // negative regulation of steroid biosynthetic process // inferred from electronic annotation /// 0016126 // sterol biosynthetic process // inferred from electronic annotation /// 0032933 // SREBP signaling pathway // inferred from direct assay /// 0042472 // inner ear morphogenesis // inferred from electronic annotation /// 0042474 // middle ear morphogenesis // inferred from electronic annotation /// 0044281 // small molecule metabolic process // traceable author statement /// 0045599 // negative regulation of fat cell differentiation // inferred from electronic annotation /// 0045717 // negative regulation of fatty acid biosynthetic process // inferred from electronic annotation /// 0060021 // palate development // inferred from electronic annotation /// 0060363 // cranial suture morphogenesis // inferred from electronic annotation /// 1901303 // negative regulation of cargo loading into COPII-coated vesicle // inferred from mutant phenotype,0005783 // endoplasmic reticulum // inferred from direct assay /// 0005789 // endoplasmic reticulum membrane // traceable author statement /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0032937 // SREBP-SCAP-Insig complex // inferred from direct assay,-0.189788692,0.004017901,TRUE
221591_s_at,FAM64A,54478,ENSG00000129195 /// OTTHUMG00000177832,"family with sequence similarity 64, member A",0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation,0005634 // nucleus // inferred from direct assay /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay,-0.234831909,0.004008513,TRUE
208066_s_at,GTF2B,2959,ENSG00000137947 /// OTTHUMG00000010611,general transcription factor IIB,"0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006352 // DNA-templated transcription, initiation // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006366 // transcription from RNA polymerase II promoter // traceable author statement /// 0006367 // transcription initiation from RNA polymerase II promoter // traceable author statement /// 0006368 // transcription elongation from RNA polymerase II promoter // traceable author statement /// 0010467 // gene expression // traceable author statement /// 0016032 // viral process // traceable author statement /// 0019048 // modulation by virus of host morphology or physiology // inferred from electronic annotation",0005634 // nucleus // inferred from electronic annotation /// 0005654 // nucleoplasm // traceable author statement,0.131736793,0.004055969,TRUE
219690_at,IGFLR1,79713,ENSG00000126246 /// ENSG00000267120 /// OTTHUMG00000182064 /// OTTHUMG00000182065,IGF-like family receptor 1,---,0005634 // nucleus // inferred from electronic annotation /// 0005886 // plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation,-0.179996111,0.004042921,TRUE
213599_at,OIP5,11339,ENSG00000104147 /// OTTHUMG00000130251,Opa interacting protein 5,0006334 // nucleosome assembly // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007154 // cell communication // non-traceable author statement /// 0034080 // centromere-specific nucleosome assembly // traceable author statement /// 0051301 // cell division // inferred from electronic annotation,"0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from electronic annotation /// 0005730 // nucleolus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0010369 // chromocenter // inferred from electronic annotation /// 0015030 // Cajal body // inferred from direct assay",-0.219732334,0.004064807,TRUE
203046_s_at,TIMELESS,8914,ENSG00000111602 /// OTTHUMG00000170600,timeless circadian clock,"0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from sequence or structural similarity /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007623 // circadian rhythm // inferred from sequence or structural similarity /// 0009582 // detection of abiotic stimulus // traceable author statement /// 0009628 // response to abiotic stimulus // traceable author statement /// 0009790 // embryo development // inferred from electronic annotation /// 0030324 // lung development // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from mutant phenotype /// 0042752 // regulation of circadian rhythm // inferred from mutant phenotype /// 0044770 // cell cycle phase transition // inferred from mutant phenotype /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0048511 // rhythmic process // inferred from electronic annotation /// 0048754 // branching morphogenesis of an epithelial tube // inferred from electronic annotation /// 0051301 // cell division // inferred from electronic annotation",0000790 // nuclear chromatin // inferred from direct assay /// 0005634 // nucleus // inferred by curator /// 0005634 // nucleus // inferred from direct assay,-0.21207416,0.004061155,TRUE
219262_at,SUV39H2,79723,ENSG00000152455 /// OTTHUMG00000017718,suppressor of variegation 3-9 homolog 2 (Drosophila),"0006333 // chromatin assembly or disassembly // inferred from mutant phenotype /// 0006338 // chromatin remodeling // inferred from direct assay /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0007140 // male meiosis // inferred from electronic annotation /// 0016568 // chromatin modification // inferred from electronic annotation /// 0030154 // cell differentiation // inferred from electronic annotation /// 0032259 // methylation // inferred from electronic annotation /// 0034968 // histone lysine methylation // inferred from electronic annotation /// 0036123 // histone H3-K9 dimethylation // inferred from sequence or structural similarity /// 0036124 // histone H3-K9 trimethylation // inferred from sequence or structural similarity /// 0042754 // negative regulation of circadian rhythm // inferred from sequence or structural similarity /// 0045892 // negative regulation of transcription, DNA-templated // inferred from sequence or structural similarity /// 0048511 // rhythmic process // inferred from electronic annotation /// 0051567 // histone H3-K9 methylation // inferred from electronic annotation","0000775 // chromosome, centromeric region // inferred from electronic annotation /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from electronic annotation /// 0005694 // chromosome // inferred from electronic annotation /// 0005720 // nuclear heterochromatin // inferred from electronic annotation",-0.057728053,0.004139885,TRUE
219264_s_at,LOC102725016 /// PPP2R3B,28227 /// 102725016,ENSG00000167393 /// OTTHUMG00000021052,"serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta-like /// protein phosphatase 2, regulatory subunit B'', beta",0000082 // G1/S transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006470 // protein dephosphorylation // inferred from sequence or structural similarity /// 0007050 // cell cycle arrest // traceable author statement /// 0050790 // regulation of catalytic activity // traceable author statement,0000159 // protein phosphatase type 2A complex // inferred from sequence or structural similarity /// 0005634 // nucleus // traceable author statement /// 0005654 // nucleoplasm // traceable author statement,-0.087561544,0.004142478,TRUE
206864_s_at,HRK,8739,ENSG00000135116 /// OTTHUMG00000169328,"harakiri, BCL2 interacting protein",0006915 // apoptotic process // inferred from electronic annotation /// 0032464 // positive regulation of protein homooligomerization // inferred from direct assay /// 0042981 // regulation of apoptotic process // inferred from electronic annotation /// 0043065 // positive regulation of apoptotic process // inferred from mutant phenotype /// 0090200 // positive regulation of release of cytochrome c from mitochondria // inferred from direct assay,0005739 // mitochondrion // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation,0.233580428,0.004244937,TRUE
209136_s_at,USP10,9100,ENSG00000103194 /// OTTHUMG00000176770,ubiquitin specific peptidase 10,"0006281 // DNA repair // inferred from electronic annotation /// 0006508 // proteolysis // inferred from electronic annotation /// 0006511 // ubiquitin-dependent protein catabolic process // inferred from electronic annotation /// 0006914 // autophagy // inferred from electronic annotation /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0010506 // regulation of autophagy // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from direct assay /// 0016579 // protein deubiquitination // inferred from mutant phenotype /// 0030330 // DNA damage response, signal transduction by p53 class mediator // inferred from mutant phenotype",0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0005768 // endosome // inferred from electronic annotation /// 0005769 // early endosome // inferred from direct assay /// 0045111 // intermediate filament cytoskeleton // inferred from direct assay,-0.153102288,0.004238327,TRUE
203062_s_at,MDC1,9656,ENSG00000137337 /// ENSG00000206481 /// ENSG00000224587 /// ENSG00000225589 /// ENSG00000228575 /// ENSG00000231135 /// ENSG00000234012 /// ENSG00000237095 /// OTTHUMG00000004846 /// OTTHUMG00000031075 /// OTTHUMG00000031345 /// OTTHUMG00000133719 /// OTTHUMG00000148757 /// OTTHUMG00000148951 /// OTTHUMG00000149229 /// OTTHUMG00000149465,mediator of DNA-damage checkpoint 1,0000724 // double-strand break repair via homologous recombination // traceable author statement /// 0006281 // DNA repair // traceable author statement /// 0006302 // double-strand break repair // traceable author statement /// 0006974 // cellular response to DNA damage stimulus // inferred from electronic annotation /// 0007049 // cell cycle // inferred from electronic annotation /// 0031573 // intra-S DNA damage checkpoint // traceable author statement,0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // inferred from sequence or structural similarity /// 0005730 // nucleolus // inferred from direct assay /// 0005925 // focal adhesion // inferred from direct assay,-0.197601686,0.004284516,TRUE
221369_at,MTNR1A,4543,ENSG00000168412 /// OTTHUMG00000185575,melatonin receptor 1A,"0007165 // signal transduction // inferred from electronic annotation /// 0007186 // G-protein coupled receptor signaling pathway // inferred from electronic annotation /// 0007187 // G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger // traceable author statement /// 0007617 // mating behavior // traceable author statement /// 0007623 // circadian rhythm // traceable author statement /// 0030828 // positive regulation of cGMP biosynthetic process // inferred from direct assay",0005886 // plasma membrane // traceable author statement /// 0005887 // integral component of plasma membrane // inferred from direct assay /// 0016020 // membrane // inferred from electronic annotation /// 0016021 // integral component of membrane // inferred from electronic annotation /// 0043235 // receptor complex // inferred from direct assay,0.039322851,0.004276646,TRUE
202338_at,TK1,7083,ENSG00000167900 /// OTTHUMG00000150674,"thymidine kinase 1, soluble",0001889 // liver development // inferred from electronic annotation /// 0006139 // nucleobase-containing compound metabolic process // traceable author statement /// 0006206 // pyrimidine nucleobase metabolic process // traceable author statement /// 0006260 // DNA replication // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // inferred from electronic annotation /// 0009157 // deoxyribonucleoside monophosphate biosynthetic process // traceable author statement /// 0009165 // nucleotide biosynthetic process // not recorded /// 0009636 // response to toxic substance // inferred from electronic annotation /// 0014856 // skeletal muscle cell proliferation // inferred from electronic annotation /// 0016310 // phosphorylation // inferred from electronic annotation /// 0031667 // response to nutrient levels // inferred from electronic annotation /// 0043097 // pyrimidine nucleoside salvage // traceable author statement /// 0044281 // small molecule metabolic process // traceable author statement /// 0046104 // thymidine metabolic process // inferred from electronic annotation /// 0046688 // response to copper ion // inferred from electronic annotation /// 0048565 // digestive tract development // inferred from electronic annotation /// 0051289 // protein homotetramerization // inferred from physical interaction /// 0051414 // response to cortisol // inferred from electronic annotation /// 0055086 // nucleobase-containing small molecule metabolic process // traceable author statement /// 0060138 // fetal process involved in parturition // inferred from electronic annotation,0005737 // cytoplasm // inferred from electronic annotation /// 0005829 // cytosol // traceable author statement,-0.204219012,0.004302122,TRUE
219146_at,TEFM,79736,ENSG00000172171 /// OTTHUMG00000179029,"transcription elongation factor, mitochondrial","0006119 // oxidative phosphorylation // inferred from mutant phenotype /// 0006259 // DNA metabolic process // inferred from direct assay /// 0006264 // mitochondrial DNA replication // inferred from mutant phenotype /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006390 // transcription from mitochondrial promoter // inferred from mutant phenotype",0005739 // mitochondrion // inferred from direct assay /// 0005759 // mitochondrial matrix // inferred from direct assay /// 0030529 // ribonucleoprotein complex // inferred from direct assay /// 0042645 // mitochondrial nucleoid // inferred from direct assay,-0.124222048,0.00436523,TRUE
212320_at,TUBB,203068,ENSG00000183311 /// ENSG00000196230 /// ENSG00000224156 /// ENSG00000227739 /// ENSG00000229684 /// ENSG00000232421 /// ENSG00000232575 /// ENSG00000235067 /// OTTHUMG00000004838 /// OTTHUMG00000031059 /// OTTHUMG00000031329 /// OTTHUMG00000133718 /// OTTHUMG00000148754 /// OTTHUMG00000148943 /// OTTHUMG00000149222 /// OTTHUMG00000149458,"tubulin, beta class I",0000086 // G2/M transition of mitotic cell cycle // traceable author statement /// 0000278 // mitotic cell cycle // traceable author statement /// 0006184 // GTP catabolic process // inferred from electronic annotation /// 0006928 // cellular component movement // traceable author statement /// 0007017 // microtubule-based process // traceable author statement /// 0009987 // cellular process // inferred from direct assay /// 0030705 // cytoskeleton-dependent intracellular transport // traceable author statement /// 0042267 // natural killer cell mediated cytotoxicity // non-traceable author statement /// 0051225 // spindle assembly // inferred from electronic annotation /// 0051258 // protein polymerization // inferred from electronic annotation /// 0051297 // centrosome organization // inferred from electronic annotation /// 0051301 // cell division // traceable author statement,0000242 // pericentriolar material // inferred from electronic annotation /// 0005634 // nucleus // inferred from direct assay /// 0005641 // nuclear envelope lumen // inferred from direct assay /// 0005737 // cytoplasm // inferred from electronic annotation /// 0005737 // cytoplasm // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005856 // cytoskeleton // traceable author statement /// 0005874 // microtubule // inferred from direct assay /// 0005874 // microtubule // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay /// 0015630 // microtubule cytoskeleton // inferred from direct assay /// 0036464 // cytoplasmic ribonucleoprotein granule // inferred from direct assay /// 0043234 // protein complex // inferred from electronic annotation /// 0044297 // cell body // inferred from direct assay /// 0070062 // extracellular vesicular exosome // inferred from direct assay,-0.137015807,0.00434295,TRUE
212138_at,PDS5A,23244,ENSG00000121892 /// OTTHUMG00000160582,"PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)",0000278 // mitotic cell cycle // traceable author statement /// 0007049 // cell cycle // inferred from electronic annotation /// 0007067 // mitotic nuclear division // inferred from electronic annotation /// 0008156 // negative regulation of DNA replication // inferred from mutant phenotype /// 0051301 // cell division // inferred from electronic annotation,"0000775 // chromosome, centromeric region // traceable author statement /// 0000785 // chromatin // inferred from direct assay /// 0005634 // nucleus // inferred from direct assay /// 0005654 // nucleoplasm // traceable author statement /// 0005694 // chromosome // traceable author statement /// 0005730 // nucleolus // inferred from direct assay /// 0005829 // cytosol // traceable author statement /// 0005886 // plasma membrane // inferred from direct assay",-0.121041939,0.004361394,TRUE
215933_s_at,HHEX,3087,ENSG00000152804 /// OTTHUMG00000018762,hematopoietically expressed homeobox,"0000122 // negative regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0001570 // vasculogenesis // inferred from electronic annotation /// 0001701 // in utero embryonic development // inferred from electronic annotation /// 0001889 // liver development // inferred from electronic annotation /// 0002009 // morphogenesis of an epithelium // inferred from electronic annotation /// 0002573 // myeloid leukocyte differentiation // inferred from electronic annotation /// 0006351 // transcription, DNA-templated // inferred from electronic annotation /// 0006355 // regulation of transcription, DNA-templated // inferred from electronic annotation /// 0006357 // regulation of transcription from RNA polymerase II promoter // inferred from electronic annotation /// 0006406 // mRNA export from nucleus // inferred from direct assay /// 0007049 // cell cycle // inferred from direct assay /// 0007165 // signal transduction // inferred from electronic annotation /// 0007275 // multicellular organismal development // inferred from electronic annotation /// 0007492 // endoderm development // inferred from electronic annotation /// 0008283 // cell proliferation // inferred from direct assay /// 0009611 // response to wounding // inferred from electronic annotation /// 0009887 // organ morphogenesis // inferred from electronic annotation /// 0009952 // anterior/posterior pattern specification // inferred from sequence or structural similarity /// 0010621 // negative regulation of transcription by transcription factor localization // inferred by curator /// 0010944 // negative regulation of transcription by competitive promoter binding // traceable author statement /// 0016055 // Wnt signaling pathway // inferred from electronic annotation /// 0016525 // negative regulation of angiogenesis // inferred from sequence or structural similarity /// 0016973 // poly(A)+ mRNA export from nucleus // inferred from mutant phenotype /// 0022027 // interkinetic nuclear migration // inferred from electronic annotation /// 0030097 // hemopoiesis // inferred from electronic annotation /// 0030154 // cell differentiation // inferred by curator /// 0030177 // positive regulation of Wnt signaling pathway // inferred from sequence or structural similarity /// 0030183 // B cell differentiation // inferred from sequence or structural similarity /// 0030878 // thyroid gland development // inferred from electronic annotation /// 0030900 // forebrain development // inferred from electronic annotation /// 0030948 // negative regulation of vascular endothelial growth factor receptor signaling pathway // inferred from sequence or structural similarity /// 0031016 // pancreas development // inferred from electronic annotation /// 0034504 // protein localization to nucleus // inferred from direct assay /// 0035050 // embryonic heart tube development // inferred from electronic annotation /// 0035264 // multicellular organism growth // inferred from electronic annotation /// 0042127 // regulation of cell proliferation // inferred from electronic annotation /// 0043434 // response to peptide hormone // inferred from electronic annotation /// 0045736 // negative regulation of cyclin-dependent protein serine/threonine kinase activity // inferred from direct assay /// 0045892 // negative regulation of transcription, DNA-templated // inferred from direct assay /// 0045944 // positive regulation of transcription from RNA polymerase II promoter // inferred from direct assay /// 0048568 // embryonic organ development // inferred from electronic annotation /// 0048729 // tissue morphogenesis // inferred from electronic annotation /// 0048853 // forebrain morphogenesis // inferred from electronic annotation /// 0060431 // primary lung bud formation // inferred from electronic annotation /// 0061009 // common bile duct development // inferred from electronic annotation /// 0061010 // gall bladder development // inferred from electronic annotation /// 0061011 // hepatic duct development // inferred from electronic annotation /// 0061017 // hepatoblast differentiation // inferred from electronic annotation /// 0070365 // hepatocyte differentiation // inferred from electronic annotation /// 0071103 // DNA conformation change // inferred from direct assay /// 0090009 // primitive streak formation // inferred from electronic annotation",0005634 // nucleus // inferred from direct assay /// 0005737 // cytoplasm // inferred from direct assay /// 0032993 // protein-DNA complex // inferred from direct assay,-0.143696521,0.004493155,TRUE