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Effects of repeated doses of 4OHT. Haematoxylin and eosin stained sections of wild type (WT), K15ΔNβ-cateninER (K15) and ∆K5ΔNβ-cateninER (ΔK5) transgenic skin treated with 4OHT for 7 days (A, E, I, Q, R), 14 days (B, F, J, S), 21 days (C, G, K, M, N, P), or 21 days + 21 days recovery (D, H, L, O). Note cysts in (N, O) and conversion of sebaceous glands into ectopic hair follicles in (Q–S). Scale bars: 50 µm.
