(Q37098969)

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Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans

scientific article published on 20 May 2016

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Europe PubMed Central

PMC publication ID

18 August 2017

Comprehensive Analysis of Mouse Bitter Taste Receptors Reveals Different Molecular Receptive Ranges for Orthologous Receptors in Mice and Humans (English)

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Europe PubMed Central

PMC publication ID

18 August 2017

Wolfgang Meyerhof

7

object named as

Wolfgang Meyerhof

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Europe PubMed Central

PMC publication ID

18 August 2017

Federica Pollastro

5

object named as

Federica Pollastro

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Europe PubMed Central

PMC publication ID

18 August 2017

author name string

Kristina Lossow

1

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Sandra Hübner

2

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Natacha Roudnitzky

3

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Jay P Slack

4

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Europe PubMed Central

PMC publication ID

18 August 2017

Maik Behrens

6

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Europe PubMed Central

PMC publication ID

18 August 2017

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publication date

20 May 2016

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Europe PubMed Central

PMC publication ID

18 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PMC publication ID

18 August 2017

291

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Europe PubMed Central

PMC publication ID

18 August 2017

29

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

15358-15377

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

Responsiveness of G protein-coupled odorant receptors is partially attributed to the activation mechanism

1 reference

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14 September 2017

Functional Analyses of Bitter Taste Receptors in Domestic Cats (Felis catus)

1 reference

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A functional comparison of the domestic cat bitter receptors Tas2r38 and Tas2r43 with their human orthologs

1 reference

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14 September 2017

Molecular evidence for the loss of three basic tastes in penguins.

1 reference

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14 September 2017

TAS2R bitter taste receptors regulate thyroid function

1 reference

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The loss of taste genes in cetaceans

1 reference

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14 September 2017

Positive Darwinian selection in the singularly large taste receptor gene family of an 'ancient' fish, Latimeria chalumnae

1 reference

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14 September 2017

Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes.

1 reference

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14 September 2017

Massive losses of taste receptor genes in toothed and baleen whales

1 reference

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14 September 2017

A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131

1 reference

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14 September 2017

Diet shapes the evolution of the vertebrate bitter taste receptor gene repertoire.

1 reference

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14 September 2017

Coarse-grained/molecular mechanics of the TAS2R38 bitter taste receptor: experimentally-validated detailed structural prediction of agonist binding

1 reference

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14 September 2017

Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart

1 reference

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14 September 2017

Major haplotypes of the human bitter taste receptor TAS2R41 encode functional receptors for chloramphenicol

1 reference

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14 September 2017

The human bitter taste receptor TAS2R10 is tailored to accommodate numerous diverse ligands.

1 reference

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14 September 2017

T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection

1 reference

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14 September 2017

Genetic labeling of Tas1r1 and Tas2r131 taste receptor cells in mice

1 reference

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14 September 2017

Functional characterization of bitter-taste receptors expressed in mammalian testis.

1 reference

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14 September 2017

Bitter taste receptor research comes of age: from characterization to modulation of TAS2Rs

1 reference

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14 September 2017

Falcarindiol allosterically modulates GABAergic currents in cultured rat hippocampal neurons.

1 reference

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14 September 2017

Major taste loss in carnivorous mammals.

1 reference

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14 September 2017

Depletion of bitter taste transduction leads to massive spermatid loss in transgenic mice

1 reference

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14 September 2017

Soy isoflavones and other isoflavonoids activate the human bitter taste receptors hTAS2R14 and hTAS2R39.

1 reference

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14 September 2017

BitterDB: a database of bitter compounds

1 reference

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14 September 2017

Gustatory and extragustatory functions of mammalian taste receptors

1 reference

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14 September 2017

Bitter taste receptors and α-gustducin regulate the secretion of ghrelin with functional effects on food intake and gastric emptying

1 reference

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14 September 2017

Expression of taste receptors in solitary chemosensory cells of rodent airways

1 reference

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14 September 2017

Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor

1 reference

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14 September 2017

Structural requirements of bitter taste receptor activation

1 reference

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14 September 2017

Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signals.

1 reference

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14 September 2017

ETE: a python Environment for Tree Exploration

1 reference

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14 September 2017

The Molecular Receptive Ranges of Human TAS2R Bitter Taste Receptors

1 reference

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14 September 2017

The human bitter taste receptor hTAS2R50 is activated by the two natural bitter terpenoids andrographolide and amarogentin

1 reference

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14 September 2017

Dynamic evolution of bitter taste receptor genes in vertebrates

1 reference

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14 September 2017

Bitter taste receptors influence glucose homeostasis

1 reference

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14 September 2017

Origin of the genetic components of the vomeronasal system in the common ancestor of all extant vertebrates

1 reference

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14 September 2017

SREBP-2 regulates gut peptide secretion through intestinal bitter taste receptor signaling in mice

1 reference

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14 September 2017

Bitter peptides activate hTAS2Rs, the human bitter receptors

1 reference

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14 September 2017

The diploid genome sequence of an individual human

1 reference

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14 September 2017

Non-genomic steroid actions in human spermatozoa. "Persistent tickling from a laden environment".

1 reference

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14 September 2017

Independent evolution of bitter-taste sensitivity in humans and chimpanzees

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14 September 2017

Elucidation of mammalian bitter taste

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14 September 2017

Inbred mouse strains C57BL/6J and DBA/2J vary in sensitivity to a subset of bitter stimuli

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14 September 2017

Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice

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14 September 2017

Genomic organization, expression, and function of bitter taste receptors (T2R) in mouse and rat

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14 September 2017

The receptors and coding logic for bitter taste

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14 September 2017

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates

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14 September 2017

The molecular basis of individual differences in phenylthiocarbamide and propylthiouracil bitterness perception

1 reference

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14 September 2017

Bitter taste receptors for saccharin and acesulfame K.

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14 September 2017

Umami taste responses are mediated by alpha-transducin and alpha-gustducin

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14 September 2017

Quorum sensing and signal interference: diverse implications

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14 September 2017

Identification of ligands for two human bitter T2R receptors

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14 September 2017

The human taste receptor hTAS2R14 responds to a variety of different bitter compounds

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14 September 2017

Receptors for bitter, sweet and umami taste couple to inhibitory G protein signaling pathways

1 reference

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14 September 2017

Worms taste bitter: ASH neurons, QUI-1, GPA-3 and ODR-3 mediate quinine avoidance in Caenorhabditis elegans

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14 September 2017

Functional interaction between T2R taste receptors and G-protein alpha subunits expressed in taste receptor cells

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14 September 2017

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

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14 September 2017

Evolutionary relationships of the Tas2r receptor gene families in mouse and human

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14 September 2017

Adaptive diversification of bitter taste receptor genes in Mammalian evolution

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14 September 2017

Positional cloning of the human quantitative trait locus underlying taste sensitivity to phenylthiocarbamide

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14 September 2017

Initial sequencing and comparative analysis of the mouse genome

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14 September 2017

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides

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14 September 2017

Role of saliva in the maintenance of taste sensitivity

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14 September 2017

Presence of a plasma membrane targeting sequence in the amino-terminal region of the rat somatostatin receptor 3.

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14 September 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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14 September 2017

High-resolution genetic mapping of the sucrose octaacetate taste aversion (Soa) locus on mouse Chromosome 6

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14 September 2017

Taste receptor cells that discriminate between bitter stimuli

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14 September 2017

Bitter taste, phytonutrients, and the consumer: a review

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14 September 2017

A family of candidate taste receptors in human and mouse

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14 September 2017

T2Rs function as bitter taste receptors

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14 September 2017

A novel family of mammalian taste receptors

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14 September 2017

Identification of ligands for olfactory receptors by functional expression of a receptor library

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14 September 2017

Multiple sequence alignment with Clustal X

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14 September 2017

Characterization and solubilization of bitter-responsive receptors that couple to gustducin

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14 September 2017

Transduction of bitter and sweet taste by gustducin

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14 September 2017

Coupling of bitter receptor to phosphodiesterase through transducin in taste receptor cells

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14 September 2017

Progressive sequence alignment as a prerequisite to correct phylogenetic trees

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14 September 2017

Gustatory expression pattern of the human TAS2R bitter receptor gene family reveals a heterogenous population of bitter responsive taste receptor cells.

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29 September 2017

Characterization of ligands for fish taste receptors.

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29 September 2017

Bitter stimuli induce Ca2+ signaling and CCK release in enteroendocrine STC-1 cells: role of L-type voltage-sensitive Ca2+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

29 September 2017

Functional diversity of bitter taste receptor TAS2R16 in primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

27 June 2018

Modulation of bitter taste perception by a small molecule hTAS2R antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

27 June 2018

A common polygenic basis for quinine and PROP avoidance in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

27 June 2018

Behavioral specificity of the bitter taste gene Soa.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

27 June 2018

Genetics of bitter perception in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

27 June 2018

Response characteristics of three taste nerves in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

27 June 2018

Single-locus control of sucrose octaacetate tasting among mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

27 June 2018

Tuning properties of avian and frog bitter taste receptors dynamically fit gene repertoire sizes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Frequent expansions of the bitter taste receptor gene repertoire during evolution of mammals in the Euarchontoglires clade.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Dysregulation of brain olfactory and taste receptors in AD, PSP and CJD, and AD-related model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Functional genomics reveals dysregulation of cortical olfactory receptors in Parkinson disease: novel putative chemoreceptors in the human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Different phenolic compounds activate distinct human bitter taste receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Neuronal expression of bitter taste receptors and downstream signaling molecules in the rat brainstem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Acyl homoserine lactones induce early response in the airway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Quorum sensing, communication and cross-kingdom signalling in the bacterial world.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Broad tuning of the human bitter taste receptor hTAS2R46 to various sesquiterpene lactones, clerodane and labdane diterpenoids, strychnine, and denatonium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Functional characterization of human bitter taste receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

The relative affective potency of glycine, L-serine and sucrose as assessed by a brief-access taste test in inbred strains of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Taste sensitivities to PROP and PTC vary independently in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Diterpenoids from Cascarilla (Croton eluteria Bennet).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

A high-throughput screening procedure for identifying mice with aberrant taste and oromotor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

A brief-access test for bitter taste in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4946946

3 September 2018

Functional bitter taste receptors are expressed in brain cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetics of tasting in mice. IV. The acetates of raffinose, galactose and beta-lactose

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contrasting modes of evolution between vertebrate sweet/umami receptor genes and bitter receptor genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetics of tasting in mice. VII. Glycine revisited, and the chromosomal location of Sac and Soa

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Taste of Health: Nature's Bitter Gifts

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosome mapping ofSoa, a gene influencing gustatory sensitivity to sucrose octaacetate in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetics of tasting in mice. III. Quinine

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amino acids and peptides activate at least five members of the human bitter taste receptor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetics of tasting in mice. V. Glycine and cycloheximide

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Taste Polymorphism in Mice involving a Bitter Sugar Derivative

1 reference

https://pubmed.ncbi.nlm.nih.gov/27226572

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M116.718544

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

18 August 2017

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