(Q21115051)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P28566

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

G protein-coupled receptor activity

Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

5 June 2018

signal transducer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

1 reference

31 October 2017

serotonin binding

1 reference

8 April 2019

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

G protein-coupled serotonin receptor activity

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

5 June 2018

Toward Selective Drug Development for the Human 5-Hydroxytryptamine 1E Receptor: A Comparison of 5-Hydroxytryptamine 1E and 1F Receptor Structure-Affinity Relationships

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

5 June 2018

5 June 2018

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

neurotransmitter receptor activity

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

protein binding

IPI

1 reference

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

G protein-coupled receptor activity

IPI

Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

G protein-coupled serotonin receptor activity

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

Toward Selective Drug Development for the Human 5-Hydroxytryptamine 1E Receptor: A Comparison of 5-Hydroxytryptamine 1E and 1F Receptor Structure-Affinity Relationships

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

8 April 2019

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

integral component of plasma membrane

cell component

Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

5 June 2018

Toward Selective Drug Development for the Human 5-Hydroxytryptamine 1E Receptor: A Comparison of 5-Hydroxytryptamine 1E and 1F Receptor Structure-Affinity Relationships

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

5 June 2018

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

1 reference

8 April 2019

integral component of plasma membrane

Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

Toward Selective Drug Development for the Human 5-Hydroxytryptamine 1E Receptor: A Comparison of 5-Hydroxytryptamine 1E and 1F Receptor Structure-Affinity Relationships

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

dendrite

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

G protein-coupled receptor signaling pathway

biological process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

4 references

8 April 2019

8 April 2019

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

1 reference

5 June 2018

Molecular cloning of a human gene (S31) encoding a novel serotonin receptor mediating inhibition of adenylyl cyclase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P28566&geneProductId=UniProtKB:P28566

adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

IMP

1 reference

8 April 2019

Toward Selective Drug Development for the Human 5-Hydroxytryptamine 1E Receptor: A Comparison of 5-Hydroxytryptamine 1E and 1F Receptor Structure-Affinity Relationships

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

IMP

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

1 reference

8 April 2019

G protein-coupled serotonin receptor signaling pathway

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

chemical synaptic transmission

Molecular cloning of a serotonin receptor from human brain (5HT1E): a fifth 5HT1-like subtype

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P28566

physically interacts with

1 reference

218

17 August 2016

5-carboxamidotryptamine

1 reference

4

17 August 2016

1 reference

5

N,N-dimethyl-5-methoxytryptamine

17 August 2016

1 reference

145

17 August 2016

1 reference

107

(+/-)-8-hydroxy-2-(di-N-propylamino)tetralin

17 August 2016

1 reference

7

17 August 2016

1 reference

152

17 August 2016

1 reference

3927

17 August 2016

1 reference

38

17 August 2016

1 reference

121

4-iodo-2,5-dimethoxyphenylisopropylamine

17 August 2016

1 reference

147

17 August 2016

1 reference

39

17 August 2016

1 reference

40

17 August 2016

1 reference

12

17 August 2016

1 reference

148

17 August 2016

1 reference

149

17 August 2016

1 reference

123

17 August 2016

1 reference

45

17 August 2016

1 reference

47

17 August 2016

1 reference

50

17 August 2016

1 reference

51

17 August 2016

1 reference

54

1-(3-trifluoromethylphenyl)piperazine

17 August 2016

1 reference

115

17 August 2016

1 reference

125

17 August 2016

1 reference

57

17 August 2016

1 reference

59

17 August 2016

1 reference

60

17 August 2016

1 reference

10

17 August 2016

1 reference

14

17 August 2016

m-chlorophenylpiperazine

1 reference

142

17 August 2016

1 reference

3

17 August 2016

1 reference

85

17 August 2016

1 reference

133

17 August 2016

1 reference

89

17 August 2016

1 reference

150

17 August 2016

1 reference

134

17 August 2016

1 reference

136

17 August 2016

1 reference

96

17 August 2016

1 reference

98

17 August 2016

1 reference

102

17 August 2016

1 reference

103

GPCR, rhodopsin-like, 7TM

17 August 2016

has part(s)

1 reference

InterPro Release 71.0