Horrors of Malformed Men is a quite experimental movie by veteran director Ishii Teruo that has been inspired by the tales of famous mystery and horror author Edogawa Rampo who had himself been inspired by Western authors such as Edgar Allan Poe. This experimental movie at the pulse of its time combines several of these tales. The main issue is that this fusion isn't always fluid and leads to two completely contrasting parts.
The first half of the movie is a murder mystery tale. A medical student without any recollection of his past is trapped in a sinister asylum. He manages to escape when one of the guards attempts to murder him. The fugitive discovers the photograph of a recently deceased man from a prosperous family who looks exactly like him. The medical student decides to take the dead man's identity to find out the truth about his origins and escape from the police.
The second half of the movie is a supernatural horror tale. The medical student travels to the island of a mad scientist who transforms perfectly normal humans into hideous freaks to create a better society. He gets captured, manipulated and threatened by the scientist and attempts to escape the island and prevent the scientist's megalomanic plans.
It's probably a matter of prefence whether you prefer the first or the second half of the movie but they are so different from each other that few people will equally appreciate both parts. The first half is atmospheric, mysterious and surprising as it convinces with clever storytelling and intriguing characters. It recalls numerous European murder mystery films as especially the German Edgar Wallace films and the Italian giallo genre come to mind. The second half is much more brutal, experimental and frantic and ventures into experimental cinematography with hectic camera work, numerous flashbacks and colourful locations. It's a mixture of Japan's very own pink film genre of the sixties and American pre-war science-fiction and horror cinema somewhere between King Kong and Island of Lost Souls.
In the end, Horrors of Malformed Men is certainly daring, entertaining and unconventional. However, the script is all over the place and the conclusion might even be too unconventional for most open-minded cineasts. Ishii Teruo should have created two different movies here instead of putting together two ideas that don't gel.