- He sat out of show business briefly while he underwent treatment for thyroid cancer from 1981 to 1982.
- He was Inducted into the New Jersey Hall of Fame in 2013 for his services to arts and entertainment.
- He worked with Eddie Murphy on Saturday Night Live (1975). They became very good friends and Murphy even bought a home in his neighbourhood in 1982. They produced a short film for SNL about his street behaviour fitting in with the New Jersey suburbs.
- Is mentioned, along with Vanessa Redgrave and Eddie Murphy in the song Jammin' Me, by Tom Petty & The Heartbreakers.
- Martial arts student of Wing Chun master Alan Goldberg.
- He's the guy in the trench coat in Billy Joel's Keepin' The Faith music video.
- In January 2014, Joe became the Morning Drive radio host of "Joe in the Morning" on WNYM (AM 970 in New York City).
- Living in Lebanon Township, New Jersey. (2010)
- Did some outrageous Miller Lite commercials in the 1980s.
- He graduated from West Essex High School in Caldwell, New Jersey in 1969.
- His wife, Kimberly Driscoll, gave birth to their third child, daughter Olivia, on 29 November 2004.
- Childhood friendship with Judge Andrew Napolitano in Bloomsfield, N.J.
- He has four children: Joey Piscopo, born in 1979 (with Nancy Jones); Alexandra, Michael and Olivia (with Kimberly Driscoll).
- Surname is pronounced "pis-KUH-poh".
- Fan of the New Jersey Devils.
- Graduated from Jones College in Jacksonville, Florida. Attended West Essex High School in New Jersey and was a member of the drama club "The Masquers".
- Starred in "Dirty Rotten Scoundrels" at the Gateway Playhouse. (August 2009)
- Hunterdon County, New Jersey (February 2011)
- Hunterdon, New Jersey (December 2010)
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