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Disentangling detrimental sand fly-mite interactions in a closed laboratory sand fly colony: implications for vector-borne disease studies and guidelines for overcoming severe mite infestations
BackgroundVector sand fly colonies are a critical component of studies aimed at improving the understanding of the neglected tropical disease...
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Azadirachtin disrupts ecdysone signaling and alters sand fly immunity
BackgroundLeishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome...
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Survey of sand fly fauna in six provinces of Southern Vietnam with species identification using DNA barcoding
BackgroundSand flies, belonging to the Psychodidae family, represent small, hairy insects that serve as significant vectors in various important...
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An integrative taxonomic approach reveals two putatively novel species of phlebotomine sand fly (Diptera: Psychodidae) in Thailand
BackgroundThe subfamily Phlebotominae comprises 1028 species of sand fly, of which only 90 are recognized as vectors of pathogenic agents such as Trypanosoma...
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Sand fly blood meal volumes and their relation to female body weight under experimental conditions
BackgroundSand fly females require a blood meal to develop eggs. The size of the blood meal is crucial for fecundity and affects the dose of...
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Report of a new species of sand fly, Phlebotomus (Anaphlebotomus) ajithii n. sp. (Diptera: Psychodidae), from Western Ghats, India
BackgroundWestern Ghats is a biodiversity treasure trove with reports of indigenous leishmaniasis cases. Hence, systematic sand fly surveillance was...
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Phlebotomine sand fly survey, blood meal source identification, and description of Sergentomyia imihra n. sp. in the central Sahara of Algeria
BackgroundPhlebotomine sand flies (Diptera: Psychodidae) are important vectors of various pathogens, mainly Leishmania parasites. In the Old World,...
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Phlebotomine sand flies (Diptera: Psychodidae) and sand fly-borne pathogens in the Greater Mekong Subregion: a systematic review
Phlebotomine sand flies are proven or suspected vectors of several pathogens of importance, including leishmaniasis, bartonellosis and sand fly...
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Safety and reactogenicity of a controlled human infection model of sand fly-transmitted cutaneous leishmaniasis
The leishmaniases are globally important parasitic diseases for which no human vaccines are currently available. To facilitate vaccine development,...
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Phlebotomine sand fly (Diptera: Phlebotominae) diversity in the foci of cutaneous leishmaniasis in the Surxondaryo Region of Uzbekistan: 50 years on
In Uzbekistan, the number of reported leishmaniasis cases is rising at the alarming rate. In this work, we studied the phlebotomine sand fly...
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Factors Affecting Leishmania Infection in Sand Fly
Leishmania is a causative agent of leishmaniasis infection. It requires two hosts to complete its life cycle, mammals and sand flies. The parasite... -
Investigating potential sand fly vectors after the first reported outbreak of cutaneous leishmaniasis in Ghana
BackgroundLeishmaniasis is a parasitic disease caused by species of the genus Leishmania , which are transmitted through the bite of infected female...
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Age, sex, and mating status discrimination in the sand fly Lutzomyia longipalpis using near infra-red spectroscopy (NIRS)
BackgroundUnderstanding aspects related to the physiology and capacity of vectors is essential for effectively controlling vector-borne diseases. The...
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Morphological and DNA-based description of Trichophoromyia peixotoi n. sp. (Diptera: Psychodidae), a new sand fly species from the Brazilian Amazon
BackgroundPhlebotomine sand flies of the genus Trichophoromyia Barretto, 1962 are of great relevance to public health as vectors of Leishmania ...
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Host–Parasite Interactions: Regulation of Leishmania Infection in Sand Fly
PurposeSand flies are the only proven vectors of leishmaniases, a tropical neglected disease endemic in at least 92 countries. Vector–parasite...
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Genetic diversity and haplotype analysis of Leishmania tropica identified in sand fly vectors of the genera Phlebotomus and Sergentomyia using next-generation sequencing technology
Next-generation sequencing (NGS) was used to investigate the genetic diversity of Leishmania tropica in the sand fly vector, targeting the internal...
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The spatial relationship between leishmaniases and sand flies in Europe and neighboring countries
BackgroundLeishmania infantum is endemic in Europe (and elsewhere) while L. donovani s.s., L. tropica and L. major are not but are present in...
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Morphological description of Pintomyia (Pifanomyia) veintemillasi n. sp., a new sand fly species from the sub-Andean region of Bolivia
BackgroundMost sand fly species are located in the Americas; some act as vectors of leishmaniasis and other human diseases. In Bolivia, about 25% of...
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Microbial ecology of sand fly breeding sites: aging and larval conditioning alter the bacterial community composition of rearing substrates
BackgroundSand flies vector several human pathogens, including Leishmania species, which cause leishmaniases. A leishmaniasis vaccine does not yet...
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Structural analysis of PpSP15 and PsSP9 sand fly salivary proteins designed with a self-cleavable linker as a live vaccine candidate against cutaneous leishmaniasis
BackgroundLeishmania parasites are deposited in the host through sand fly bites along with sand fly saliva. Therefore, salivary proteins are...