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Diagnostic value of cerebrospinal fluid Neutrophil Gelatinase-Associated Lipocalin for differentiation of bacterial meningitis from tuberculous meningitis or cryptococcal meningitis: a prospective cohort study
BackgroundThe early differential diagnosis between bacterial meningitis (BM) and tuberculous meningitis (TBM) or cryptococcal meningitis (CM) remains...
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Group A Streptococcal meningitis in children: a short case series and systematic review
BackgroundGroup A streptococcal(GAS) meningitis is a severe disease with a high case fatality rate. In the era of increasing GAS meningitis, our...
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RNA sequencing reveals differential long noncoding RNA expression profiles in bacterial and viral meningitis in children
BackgroundWe aimed to investigate the involvement of long non-coding RNA (lncRNA) in bacterial and viral meningitis in children.
Methods ...
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Molecular and Cellular Mechanism of Pathogen Invasion into the Central Nervous System: Meningitis
Meningitis, a deadly ailment that affects the central nervous system (CNS), involves the inflammation of the brain and spinal cord’s protective...
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NLRP3 Activation Contributes to Memory Impairment in an Experimental Model of Pneumococcal Meningitis
Bacterial meningitis is considered a life-threatening condition with high mortality rates. In response to the infection, signaling cascades,...
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Surgical treatment for recurrent thoracic ventral intradural arachnoid cyst secondary to tuberculous meningitis: a case report
IntroductionSpinal intradural arachnoid cysts (SIACs) are rare spinal entities that are categorized as primary or secondary pathologies. Secondary...
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Invasive Streptococcus pseudopneumoniae infection in an adult patient with acute community-acquired meningitis: a case report
Rapid identification of pathogens in acute meningitis is critical for timely treatment. However, traditional methods often face limitations in...
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Integrating DNA/RNA microbe detection and host response for accurate diagnosis, treatment and prognosis of childhood infectious meningitis and encephalitis
BackgroundInfectious meningitis/encephalitis (IM) is a severe neurological disease that can be caused by bacterial, viral, and fungal pathogens. IM...
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Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function
BackgroundBrain pericytes participate in the regulation of cerebral blood flow and the maintenance of blood–brain barrier integrity. Because of their...
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Persistent headaches one year after bacterial meningitis: prevalence, determinants and impact on quality of life
BackgroundLittle is known on headaches long-term persistence after bacterial meningitis and on their impact on patients’ quality of life.
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Brain Immune Cell Infiltration and Serum Metabolomic Characteristics Reveal that Lauric Acid Promotes Immune Cell Infiltration in Brain and Streptococcus suis Meningitis in Mice
Although naturally Streptococcus suis serotype 2 (SS2) causes meningitis resulting in death or sequela of neurological symptoms in pigs and humans,...
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Meningitis associated with HHV-7 in an Iranian immunocompetent adolescent girl
There is limited literature regarding meningitis associated with HHV-7. This article reports an immunocompetent adolescent girl who developed fever,...
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Epidemiology and antimicrobial resistance patterns of bacterial meningitis among hospitalized patients at a tertiary care hospital in Saudi Arabia: a six-year retrospective study
IntroductionBacterial meningitis poses significant medical challenges due to its acute inflammatory nature and potential for severe neurological...
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Meningitis and intracranial abscess due to Mycoplasma pneumoniae in a B cell-depleted patient with multiple sclerosis
Mycoplasma pneumoniae , a frequent respiratory pathogen, can cause neurological disease manifestations. We here present a case of M. pneumoniae as...
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The role of plasminogen activator inhibitor-2 in pneumococcal meningitis
Pneumococcal meningitis is associated with dysregulation of the coagulation cascade. Previously, we detected upregulation of cerebral plasminogen...
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Zebrafish Larvae as an Experimental Model of Cryptococcal Meningitis
This chapter provides guidance for introducing Cryptococcus neoformans into the zebrafish larvae model system to establish a CNS infection phenotype...
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Hybrid capture shotgun sequencing detected unexpected viruses in the cerebrospinal fluid of children with acute meningitis and encephalitis
PurposeInvestigation of undiagnosed cases of infectious neurological diseases, especially in the paediatric population, remains a challenge. This...
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Determine the factors affecting the time to recovery of children with bacterial meningitis at Jigjiga university referral hospital in the Somali Regional State of Ethiopia: using the parametric shared frailty and AFT models
BackgroundNeisseria meningitides, Streptococcus pneumonia, and hemophilic influenza type B are frequently linked to bacterial meningitis (BM) in...
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Occurrence and determinants of seizures and their impact on tuberculous meningitis: a prospective evaluation
ObjectiveTo assess the incidence of seizures and the factors contributing to poor outcomes in patients with tuberculous meningitis (TBM).
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