The RING-CH Ligase K5 Antagonizes Restriction of KSHV and HIV-1 Particle Release by Mediating Ubiquitin-Dependent Endosomal Degradation of Tetherin

• Claire Pardieu ,

  Contributed equally to this work with: Claire Pardieu, Raphaël Vigan

  Affiliation MRC Centre for Medical Molecular Virology, University College London, London, United Kingdom

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• Raphaël Vigan ,

  Contributed equally to this work with: Claire Pardieu, Raphaël Vigan

  Affiliation Department of Infectious Disease, King's College London School of Medicine, Guy's Hospital, London, United Kingdom

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• Sam J. Wilson,

  Affiliations MRC Centre for Medical Molecular Virology, University College London, London, United Kingdom, Howard Hughes Medical Institute, Aaron Diamond AIDS Research Center and Laboratory of Retrovirology, The Rockefeller University, New York, New York, United States of America

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• Alessandra Calvi,

  Affiliation Department of Infectious Disease, King's College London School of Medicine, Guy's Hospital, London, United Kingdom

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• Trinity Zang,

  Affiliation Howard Hughes Medical Institute, Aaron Diamond AIDS Research Center and Laboratory of Retrovirology, The Rockefeller University, New York, New York, United States of America

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• Paul Bieniasz,

  Affiliation Howard Hughes Medical Institute, Aaron Diamond AIDS Research Center and Laboratory of Retrovirology, The Rockefeller University, New York, New York, United States of America

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• Paul Kellam,

  Affiliations MRC Centre for Medical Molecular Virology, University College London, London, United Kingdom, Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom

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• Greg J. Towers ,

  * E-mail: [email protected] (GJT); [email protected] (SJDN)

  Affiliation MRC Centre for Medical Molecular Virology, University College London, London, United Kingdom

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• Stuart J. D. Neil

  * E-mail: [email protected] (GJT); [email protected] (SJDN)

  Affiliation Department of Infectious Disease, King's College London School of Medicine, Guy's Hospital, London, United Kingdom

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