Lihat sumber Allopregnanolon

{{chembox
|ImageFile=Allopregnanolone.svg
|ImageSize=200px
|IUPACName=1-(3-Hidroksi-10,13-dimetil-<br />2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradekahidro-<br />1''H''-Siklopenta[a]<br />fenantren-17-yl)etanon
|OtherNames=3α,5α-Tetrahidroprogesteron
|Section1= {{Chembox Identifiers
|  ChemSpiderID = 17216124
| InChI = 1/C21H34O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h14-19,23H,4-12H2,1-3H3/t14?,15-,16+,17-,18+,19+,20+,21-/m1/s1
| InChIKey = AURFZBICLPNKBZ-JMTGGFPBBC
| CASNo=516-54-1
|  PubChem=262961
|  SMILES = CC(=O)[C@H]2CC[C@H]1[C@@H]3CCC4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@@]12C
}}
|Section2= {{Chembox Properties
|  Formula=C<sub>21</sub>H<sub>34</sub>O<sub>2</sub>
|  MolarMass=318,49 g/mol
|  Appearance=
|  Density=
|  MeltingPt=
|  BoilingPt=
|  Solubility=
  }}
|Section3= {{Chembox Hazards
|  MainHazards=
|  FlashPt=
|  Autoignition=
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}}

'''Allopregnanolon''' ({{lang-en|Allopregnanolone, 3α-hydroxy-5α-pregnan-20-one, 3α,5α-tetrahydroprogesterone, THP, ALLO}}) merupakan [[neurosteroid]] yang mengikat pencerap GABA. ALLO disintesis di dalam [[otak]] oleh [[neuron]] piramidal<ref>{{en}} {{cite web
| url          = http://www.ncbi.nlm.nih.gov/pubmed/18003893
| title        = Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice
| accessdate   = 2010-06-18
| work         = Psychiatric Institute, Department of Psychiatry, School of Medicine, University of Illinois at Chicago; Agís-Balboa RC, Pinna G, Pibiri F, Kadriu B, Costa E, Guidotti A.
}}</ref> dari [[progesteron]] dengan bantuan [[enzim]] 5alfa-reduktase tipe I dan 3alfa-hidroksisteroid [[dehidrogenase]].<ref>{{en}} {{cite web
| url          = http://www.ncbi.nlm.nih.gov/pubmed/16984997
| title        = Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis
| accessdate   = 2010-06-18
| work         = Department of Psychiatry, Psychiatric Institute, University of Illinois; Agís-Balboa RC, Pinna G, Zhubi A, Maloku E, Veldic M, Costa E, Guidotti A.
}}</ref>

== Rujukan ==
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[[Kategori:Steroid]]


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