Polymethylene polyphenylene isocyanate
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Names | |
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Other names
Polymeric diphenylmethane diisocyanate; Poly((phenyl isocyanate)-co-formaldehyde);
Polymethylene polyphenyl polyisocyanate
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Identifiers | |
Abbreviations | PPI |
ChEBI | |
ECHA InfoCard | 100.112.554 |
KEGG | |
CompTox Dashboard (EPA)
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Properties | |
(C8H5NO)n | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Polymethylene polyphenylene isocyanate (PPI), is a polyurea-based polymer derived from isocyanate monomers that is used in some glues, aerosol foams, plastics, paint and household products.[1]
PPI is listed as a "hazardous agent" by the National Institutes of Health because it irritates skin and breathing passages at high concentrations. Some painters exposed to PPI and related isocyanate chemicals have developed occupational asthma.[2] In chronic toxicity tests, mice exposed to low levels of PPI developed no side effects. Only those mice exposed to the two highest concentrations developed any lung symptoms.[3] The two highest doses used in this study were 1.0 and 6.0 mg per cubic meter for 6 hours each day, 5 days each week for 2 years. The duration-adjusted exposure levels for these two high concentrations are equivalent to 11 ppb and 70 ppb, 24 hours/day for two years.
References
[edit]- ^ "Polymethylene polyphenyl isocyanate". Consumer Product Information Database.
- ^ "Judge orders moth spraying halted". montereyherald.com. Archived from the original on 19 October 2007.
- ^ "Wayback Machine has not archived that URL". toxnet.nlm.nih.gov.[dead link]