Site of action of the different therapeutic tools in acromegaly. Surgery, radiotherapy, somatostatin anlogues and dopamine agonists act at the level of the pituitary adenoma, while GH-receptor antagonists act in periphery by blocking the GH receptor and thus impairing the effects of GH on the different tissues.
Date
Published: 25 June 2008
Source
Acromegaly. Orphanet Journal of Rare Diseases 2008, 3:17. doi:10.1186/1750-1172-3-17
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