English: The structure of the HIV reverse transcriptase (RT) heterodimer in complex with an RNA:DNA duplex. The reverse transcriptase p66 fragment is shown in yellow with the C-terminal RNase H domain shown in blue (active site residues in magenta spheres). The orange strand is RNA and the red strand is DNA. The p51 fragment - a differently processed protein equivalent to p66 without the RNase H domain - is shown in green.
Rendered from PDB 1HYS.
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA.
Sarafianos, S.G., Das, K., Tantillo, C., Clark Jr., A.D., Ding, J., Whitcomb, J.M., Boyer, P.L., Hughes, S.H., Arnold, E.
to share – to copy, distribute and transmit the work
to remix – to adapt the work
Under the following conditions:
attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled GNU Free Documentation License.http://www.gnu.org/copyleft/fdl.htmlGFDLGNU Free Documentation Licensetruetrue
You may select the license of your choice.
Captions
Add a one-line explanation of what this file represents
{{Information |Description ={{en|1=The structure of the HIV reverse transcriptase (RT) heterodimer in complex with an RNA:DNA duplex. The reverse transcriptase p66 fragment is shown in yellow with the C-terminal RNase H domain shown in blue (active...