Mantle zone

Mantle zone
Mantle zone
	Histology of a normal secondary lymphoid follicle, with yellow arrows pointing at the mantle zone.
	Anatomical terminology [edit on Wikidata]

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Image labeled in German, but "Mantel-zone" visible near center

The mantle zone (or just mantle) of a lymphatic nodule (or lymphatic follicle) is an outer ring of small lymphocytes surrounding a germinal center.^[1]

It is also known as the "corona".^[2]

It contains transient lymphocytes.^[3]

It is the location of the lymphoma in mantle cell lymphoma.

Pathology

Mantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e., Mantle cell lymphoma. Tcl-1 is expressed in the mantle zone.

References

^ "University of Cambridge: Department of Pathology". Archived from the original on 2008-06-03. Retrieved 2008-07-29.
^ "Lymph Nodes". Archived from the original on 2008-03-17. Retrieved 2008-07-29.
^ "Pathology of lymph nodes – Dr. Levy". www.dartmouth.edu. Archived from the original on 1999-11-05.

External links

https://web.archive.org/web/20080813003821/http://erl.pathology.iupui.edu/HISTO/LABE109.HTM
Histology image: 07102loa – Histology Learning System at Boston University — "Lymphoid Tissues and Organs: lymph node, cortex and medulla"

[1] "University of Cambridge: Department of Pathology". Archived from the original on 2008-06-03. Retrieved 2008-07-29.

[2] "Lymph Nodes". Archived from the original on 2008-03-17. Retrieved 2008-07-29.

[3] "Pathology of lymph nodes – Dr. Levy". www.dartmouth.edu. Archived from the original on 1999-11-05.

[1]

[2]

[3]