Pentolinium

Pentolinium
Identifiers
	IUPAC name 1-Methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium;
CAS Number	144-44-5 ; 52-62-0 (tartrate salt);
PubChem CID	5850;
DrugBank	DB01090;
ChemSpider	5641;
UNII	ULL76WPU5X;
ChEMBL	ChEMBL1271;
CompTox Dashboard (EPA)	DTXSID5048554 ;
Chemical and physical data
Formula	C15H32N2
Molar mass	240.43 g/mol g·mol−1
	InChI InChI=1S/C15H32N2/c1-16(12-6-7-13-16)10-4-3-5-11-17(2)14-8-9-15-17/h3-15H2,1-2H3/q+2; Key:XSBSKEQEUFOSDD-UHFFFAOYSA-N;

Pentolinium is a ganglionic blocking agent which acts as a nicotinic acetylcholine receptor antagonist. It can be used as an antihypertensive drug during surgery or to control hypertensive crises. It works by binding to the acetylcholine receptor of adrenergic nerves and thereby inhibiting the release of noradrenaline and adrenaline. Blocking this receptor leads to smooth muscle relaxation and vasodilatation. Pentolinium can be given orally, injected intramuscularly or administered intravenously.^{[citation needed]}

Overview

It's molecular formula is (C₁₅H₃₂N₂)²⁺.^[1]

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