Co-tenidone

Co-tenidone
Combination of
Atenolol	Beta blocker
Chlortalidone	Thiazide diuretic
Clinical data
Routes of; administration	Oral
Legal status
Legal status	UK: POM (Prescription only);
Identifiers
ChemSpider	151231 ;
	(verify)

Co-tenidone (BAN) is a non-proprietary name used to denote a combination of atenolol and chlortalidone. Co-tenidone is used in the treatment of hypertension. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line because they perform less well than other drugs, and because atenolol, the most frequently used β-blocker, at usual doses carries an unacceptable risk of provoking type 2 diabetes.^[1]

Formulation

Two strengths of co-tenidone are currently available in the UK:

50 mg atenolol and 12.5 mg chlortalidone, BAN of Co-tenidone 50/12.5
100 mg atenolol and 25 mg chlortalidone, BAN of Co-tenidone 100/25

References

British National Formulary 54, September 2007

Footnotes

^ Ladva S (2006-06-28). "NICE and BHS launch updated hypertension guideline". National Institute for Health and Clinical Excellence.

[NHSnews-1] Ladva S (2006-06-28). "NICE and BHS launch updated hypertension guideline". National Institute for Health and Clinical Excellence.

[1]