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Excision repair cross-complementing

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Excision repair cross-complementing (ERCC) is a set of proteins which are involved in DNA repair.[1]

In humans, ERCC proteins are transcribed from the following genes:

ERCC1, ERCC2, ERCC3, ERCC4, ERCC5, ERCC6, and ERCC8.

Members 1 though 5 are associated with Xeroderma Pigmentosum.

Members 6 and 8 are associated with Cockayne syndrome.

References

  1. ^ Wolfram Siede; Friedberg, Errol C.; Walker, Graham S. (1995). "Chapter 8: Nucleotide excision repair: mammalian genes and proteins". DNA Repair and Mutagenesis. Washington, D.C.: ASM Press. ISBN 1-55581-088-8.


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