Juvenile-hormone esterase: Difference between revisions
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In [[enzymology]], a '''[[juvenile hormone|juvenile-hormone]] esterase''' ({{EC number|3.1.1.59}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
In [[enzymology]], a '''[[juvenile hormone|juvenile-hormone]] esterase''' ({{EC number|3.1.1.59}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
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:methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H<sub>2</sub>O <math>\rightleftharpoons</math> (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol |
:methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H<sub>2</sub>O <math>\rightleftharpoons</math> (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. |
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The |
The [[substrate (biochemistry)|substrates]] of this enzyme, in addition to JH III, are [[methyl]], [[(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate]] (JHII) and [[water|H<sub>2</sub>O]] and [[methanol]] or [[methyl (2E,6E)-10R,11S-(oxiranyl)-7-ethyl-3,11-dimethyl-2,6-tridecadienoate]] (JH I) and [[water|H<sub>2</sub>O]] and [[methanol]], or [[methyl (2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienoate]] (JH0) and [[water|H<sub>2</sub>O]] and [[methanol]]. |
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This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on carboxylic [[ester]] bonds. The systematic name of this enzyme class is '''methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase'''. Other names in common use include '''JH-esterase''', '''juvenile hormone |
This enzyme belongs to the family of [[hydrolase]]s, specifically those acting on carboxylic [[ester]] bonds. The systematic name of this enzyme class is '''methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase'''. Other names in common use include '''JH-esterase''', '''juvenile hormone esterase''', and '''juvenile hormone carboxyesterase'''. |
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==References== |
==References== |
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Revision as of 04:47, 12 June 2015
| juvenile-hormone esterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.1.59 | ||||||||
| CAS no. | 50812-15-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a juvenile-hormone esterase (EC 3.1.1.59) is an enzyme that catalyzes the chemical reaction
- methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol.
The substrates of this enzyme, in addition to JH III, are methyl, (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate (JHII) and H2O and methanol or methyl (2E,6E)-10R,11S-(oxiranyl)-7-ethyl-3,11-dimethyl-2,6-tridecadienoate (JH I) and H2O and methanol, or methyl (2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrienoate (JH0) and H2O and methanol.
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name of this enzyme class is methyl-(2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate acylhydrolase. Other names in common use include JH-esterase, juvenile hormone esterase, and juvenile hormone carboxyesterase.
References
- Foucher AL, McIntosh A, Douce G, Wastling J, Tait A, Turner CM (2006). "A proteomic analysis of arsenical drug resistance in Trypanosoma brucei". Proteomics. 6 (9): 2726–32. doi:10.1002/pmic.200500419. PMID 16526094.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - Mitsui T, Riddiford LM and Bellamy G (1979). "Metabolism of juvenile hormone by the epidermis of the tobacco hornworm (Manduca sexta)". Insect Biochem. 9 (6): 637–643. doi:10.1016/0020-1790(79)90103-3.
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