Lasalocid: Difference between revisions

Lasalocid
Clinical data
AHFS/Drugs.com	International Drug Names
ATCvet code	QP51AH02 (WHO) ;
Identifiers
	IUPAC name 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-;
CAS Number	25999-31-9 ;
PubChem CID	5360807;
ChemSpider	4514598 ;
UNII	W7V2ZZ2FWB;
KEGG	D04671 ;
ChEMBL	ChEMBL145347 ;
CompTox Dashboard (EPA)	DTXSID9048485 ;
ECHA InfoCard	100.043.077
Chemical and physical data
Formula	C34H54O8
Molar mass	590.79 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)c1c(O)c(ccc1CC[C@@H](C)[C@H](O)[C@@H](C(=O)[C@@H]([C@H]3O[C@@]([C@@H]2O[C@H]([C@](O)(CC2)CC)C)(CC)C[C@@H]3C)CC)C)C;
	InChI InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1 ; Key:BBMULGJBVDDDNI-OWKLGTHSSA-N ;
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Revision as of 16:31, 23 August 2014

Lasalocid is an antibacterial agent and a coccidiostat, which is produced by strains of Streptomyces lasaliensis. It is the drug in the feed additives called Bovatec and Avatec.^[1]

Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also big organic cations like dopamine.

Horses and dogs^[2] are very susceptible to the toxic effects of Lasalocid, and it should never be administered to non-target species.

References

This antiinfective drug article is a stub. You can help Wikipedia by expanding it.

[1] FOIA Drug Summaries.

[2] BMJ Veterinary Record

[1]

[2]

Revision as of 16:29, 23 August 2014 edit 69.89.205.141 (talk) No edit summary ← Previous edit		Revision as of 16:31, 23 August 2014 edit undo 69.89.205.141 (talk) No edit summary Next edit →
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	Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also big organic cations like dopamine.		Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also big organic cations like dopamine.

	Horses and dogs<ref>[http://veterinaryrecord.bmj.com/content/155/6/174.abstract BMJ Veterinary Record]</ref> are very susceptible to the toxic effects of Lasalocid, and it should ~~not~~ be administered.		Horses and dogs<ref>[http://veterinaryrecord.bmj.com/content/155/6/174.abstract BMJ Veterinary Record]</ref> are very susceptible to the toxic effects of Lasalocid, and it should never be administered to non-target species.