Lines of Zahn: Difference between revisions
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[[Image:Lines of Zahn - intermed mag.jpg|thumb|[[Micrograph]] showing lines of Zahn (dark pink/red diagonal lines from upper left to lower right of image) in a fatal [[pulmonary embolus]]. [[H&E stain]].]] |
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'''Lines of Zahn''' are a characteristic of [[thrombus|thrombi]]<ref name="urlAtherosclerosis">{{cite web |url=http://library.med.utah.edu/WebPath/ATHHTML/ATH031.html |title=Atherosclerosis |format= |work= |accessdate=}}</ref> that appear particularly when formed in the [[heart]] or [[aorta]]. They have visible and microscopic alternating layers (laminations) of platelets mixed with fibrin, which appear lighter, and darker layers of [[red blood cell]]s.<ref name="Lee">{{cite journal| author=Lee R, Adlam D, Clelland CA, Channon KM| title=Lines of Zahn in coronary artery thrombus | journal=Eur Heart J | year= 2012 | volume= 33| issue= 9| pages= 1039| pmid=22345124 | doi=10.1093/eurheartj/ehs028}}</ref> Their presence implies thrombosis at a site of rapid blood flow that happened before death. In veins or smaller arteries, where flow is not as constant, they are less apparent. |
'''Lines of Zahn''' are a characteristic of [[thrombus|thrombi]]<ref name="urlAtherosclerosis">{{cite web |url=http://library.med.utah.edu/WebPath/ATHHTML/ATH031.html |title=Atherosclerosis |format= |work= |accessdate=}}</ref> that appear particularly when formed in the [[heart]] or [[aorta]]. They have visible and microscopic alternating layers (laminations) of platelets mixed with fibrin, which appear lighter, and darker layers of [[red blood cell]]s.<ref name="Lee">{{cite journal| author=Lee R, Adlam D, Clelland CA, Channon KM| title=Lines of Zahn in coronary artery thrombus | journal=Eur Heart J | year= 2012 | volume= 33| issue= 9| pages= 1039| pmid=22345124 | doi=10.1093/eurheartj/ehs028}}</ref> Their presence implies thrombosis at a site of rapid blood flow that happened before death. In veins or smaller arteries, where flow is not as constant, they are less apparent. |
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Revision as of 13:37, 23 September 2012
Lines of Zahn are a characteristic of thrombi[1] that appear particularly when formed in the heart or aorta. They have visible and microscopic alternating layers (laminations) of platelets mixed with fibrin, which appear lighter, and darker layers of red blood cells.[2] Their presence implies thrombosis at a site of rapid blood flow that happened before death. In veins or smaller arteries, where flow is not as constant, they are less apparent.
They are named after German pathologist Friedrich Wilhelm Zahn (1845-1904).[3]
References
- ^ "Atherosclerosis".
- ^ Lee R, Adlam D, Clelland CA, Channon KM (2012). "Lines of Zahn in coronary artery thrombus". Eur Heart J. 33 (9): 1039. doi:10.1093/eurheartj/ehs028. PMID 22345124.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ Stegman, JK, ed. (2006), Stedman's Medical Dictionary (28th ed.), Baltimore, MD: Lippincott, Williams, & Wilkins
Kumar, V. et al. (2005). Hemodynamic Disorders, Thromboembolic Disease, and Shock. Robbins and Cotran Pathologic Basis of Disease. 7th edition. Elsevier Saunders: Pennsylvania.
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