Doxanthrine: Difference between revisions

Doxanthrine
Clinical data
ATC code	none;
Identifiers
	IUPAC name (6aS,12bR)-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline-2,3-diol;
PubChem CID	15981509;
CompTox Dashboard (EPA)	DTXSID401028617 ;
Chemical and physical data
Formula	C16H15NO3
Molar mass	269.295 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Oc4cc2C3c1ccccc1CNC3COc2cc4O;
	(verify)

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Inline

Revision as of 12:55, 5 December 2011

Doxanthrine is a synthetic compound which is a potent and selective full agonist for the dopamine D₁ receptor.^[1]^[2]

^ Cueva JP, Giorgioni G, Grubbs RA, Chemel BR, Watts VJ, Nichols DE (2006). "trans-2,3-dihydroxy-6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinoline: synthesis, resolution, and preliminary pharmacological characterization of a new dopamine D1 receptor full agonist". Journal of Medicinal Chemistry. 49 (23): 6848–57. doi:10.1021/jm0604979. PMID 17154515. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)
^ Przybyla JA, Cueva JP, Chemel BR, Hsu KJ, Riese DJ, McCorvy JD, Chester JA, Nichols DE, Watts VJ (2009). "Comparison of the enantiomers of (+/-)-doxanthrine, a high efficacy full dopamine D(1) receptor agonist, and a reversal of enantioselectivity at D(1) versus alpha(2C) adrenergic receptors". European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19 (2): 138–46. doi:10.1016/j.euroneuro.2008.10.002. PMC 2636714. PMID 19028082. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link)

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	[[Category:Dopamine agonists]]		[[Category:Dopamine agonists]]
	[[Category:~~Synthetic phenolic drugs~~]]		[[Category:Catechols]]