Lasalocid: Difference between revisions

Lasalocid
Clinical data
ATCvet code	QP51AH02 (WHO) ;
Identifiers
	IUPAC name 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)- 5-ethyl-5-hydroxy-6-methyl-2-tetrahydropyranyl]-3-methyl-2-tetrahydrofuranyl]-4- hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-3-methylbenzoic acid;
CAS Number	25999-31-9;
PubChem CID	5360807;
ChemSpider	4514598 ;
KEGG	D04671 ;
ChEMBL	ChEMBL145347 ;
CompTox Dashboard (EPA)	DTXSID9048485 ;
ECHA InfoCard	100.043.077
Chemical and physical data
Formula	C34H54O8
Molar mass	590.79 g/mol g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(O)c1c(O)c(ccc1CC[C@@H](C)[C@H](O)[C@@H](C(=O)[C@@H]([C@H]3O[C@@]([C@@H]2O[C@H]([C@](O)(CC2)CC)C)(CC)C[C@@H]3C)CC)C)C;
	InChI InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1 ; Key:BBMULGJBVDDDNI-OWKLGTHSSA-N ;
	(verify)

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Revision as of 10:06, 26 June 2011

Lasalocid is an antibacterial agent and a coccidiostat, which is produced by strains of Streptomyces lasaliensis. It is the drug in the feed additive called Bovatec.^[1]

Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also big organic cations like dopamine.

It is important to note that horses and dogs^[2] are very susceptible to the toxic effects of Lasalocid, and it should not be administered.

References

This antiinfective drug article is a stub. You can help Wikipedia by expanding it.

[1] FOIA Drug Summaries.

[2] BMJ Veterinary Record

[1]

[2]

Revision as of 09:59, 26 June 2011 edit Richard Avery (talk \| contribs) Extended confirmed users 6,125 edits adding reference ← Previous edit		Revision as of 10:06, 26 June 2011 edit undo Richard Avery (talk \| contribs) Extended confirmed users 6,125 edits adding toxicity to dogs note Next edit →
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	Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also big organic cations like dopamine.		Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can transport also big organic cations like dopamine.

	It is important to note that horses are very susceptible to the toxic effects of Lasalocid, and it should not be administered.		It is important to note that horses and dogs<ref>[http://veterinaryrecord.bmj.com/content/155/6/174.abstract BMJ Veterinary Record]</ref> are very susceptible to the toxic effects of Lasalocid, and it should not be administered.