HMGA: Difference between revisions
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'''HMGA''' is a family of [[high mobility group]] proteins characterized by an [[AT-hook]]. |
'''HMGA''' is a family of [[high mobility group]] proteins characterized by an [[AT-hook]]. They code for a "small, nonhistone, chromatin-associated protein that has no intrinsic transcriptional activity but can modulate transcription by altering the chromatin architecture" (Mayr, SCIENCE) |
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A recent study has shown variations in HMGA2 to have a moderate association with adult height.<ref>{{cite web |url=http://news.bbc.co.uk/1/hi/health/6975865.stm |title=BBC NEWS | Health | Scientists discover height gene |accessdate=2007-09-03 |format= |work=}}</ref> |
A recent study has shown variations in HMGA2 to have a moderate association with adult height.<ref>{{cite web |url=http://news.bbc.co.uk/1/hi/health/6975865.stm |title=BBC NEWS | Health | Scientists discover height gene |accessdate=2007-09-03 |format= |work=}}</ref> |
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==References== |
==References== |
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<references/> |
<references/> |
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Mayr, Christine, et. al. ''Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation'', SCIENCE VOL 315, 16 Mar 2007 |
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==External links== |
==External links== |
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Revision as of 14:45, 27 September 2007
| high mobility group AT-hook 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | HMGA1 | ||||||
| Alt. symbols | HMGIY | ||||||
| NCBI gene | 3159 | ||||||
| HGNC | 5010 | ||||||
| OMIM | 600701 | ||||||
| RefSeq | NM_145901 | ||||||
| UniProt | P17096 | ||||||
| Other data | |||||||
| Locus | Chr. 6 p21 | ||||||
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| high mobility group AT-hook 2 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | HMGA2 | ||||||
| Alt. symbols | HMGIC | ||||||
| NCBI gene | 8091 | ||||||
| HGNC | 5009 | ||||||
| OMIM | 600698 | ||||||
| RefSeq | NM_003484 | ||||||
| UniProt | P52926 | ||||||
| Other data | |||||||
| Locus | Chr. 12 q15 | ||||||
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HMGA is a family of high mobility group proteins characterized by an AT-hook. They code for a "small, nonhistone, chromatin-associated protein that has no intrinsic transcriptional activity but can modulate transcription by altering the chromatin architecture" (Mayr, SCIENCE)
A recent study has shown variations in HMGA2 to have a moderate association with adult height.[1]
References
- ^ "BBC NEWS". Retrieved 2007-09-03.
{{cite web}}: Text "Health" ignored (help); Text "Scientists discover height gene" ignored (help)
Mayr, Christine, et. al. Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation, SCIENCE VOL 315, 16 Mar 2007
External links
- HMGA+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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