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Revision as of 02:22, 30 June 2022
Hans Clevers | |
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![]() Clevers in 2018 | |
Born | [2][3][4] | 27 March 1957
Nationality | Dutch |
Education | University of Utrecht |
Known for | Organoid generation and application |
Spouse | Eefke Petersen[5] |
Children | 2[2] |
Awards | Louis-Jeantet Prize for Medicine Breakthrough Prize in Life Sciences Dr A. H. Heineken Prize for Medicine Körber European Science Prize |
Scientific career | |
Fields | Molecular genetics Cell biology |
Institutions | Roche Princess Máxima Center University Medical Center Utrecht Hubrecht Institute for Developmental Biology and Stem Cell Research Utrecht University Dana–Farber Cancer Institute |
Thesis | Early events in lymphocyte activation (1985) |
Doctoral advisor | Rudy Ballieux[1] |
Johannes (Hans) Carolus Clevers (born 27 March 1957)[2][3] is a Dutch molecular geneticist, cell biologist and stem cell researcher. He became the Head of Pharma, Research and Early Development, and a member of the Corporate Executive Committee, of the Swiss healthcare company Roche in 2022.[6][7] Previously, he headed a research group at the Hubrecht Institute for Developmental Biology and Stem Cell Research[8] and at the Princess Máxima Center ;[9] he remained as an advisor and guest scientist or visiting researcher to both groups.[6] He is also a Professor in Molecular Genetics at the University of Utrecht.[7]
Early life and education
Hans Clevers was born in Eindhoven, the Netherlands in 1957.[4] He began studying biology at the University of Utrecht in 1975, but also started taking medicine in 1978,[6] in part due to his interest and in part because his friends and brothers were in the medical profession.[10] He spent 1 year in Nairobi, Kenya, and half a year at the National Institutes of Health in Bethesda, United States, for biology rotations.[10][11] He received a Doctoraal (equivalent to an MSc) in Biology in 1982 and an Artsexamen (equivalent to an MD) in 1984. Mostly because of his research background, Clevers was selected for a training position in paediatrics, and then went to pursue a PhD in 1985, under the supervision of Rudy Ballieux.[1][12][13] He obtained his PhD 1 year later.[6][10]
![](http://upload.wikimedia.org/wikipedia/en/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png)
Career
After his PhD, Clevers went to the Dana-Farber Cancer Institute as a postdoctoral researcher at Cox Terhorst's group.[7][10][14][15] In 1989, he returned to the Netherlands, joining his alma mater, the University of Utrecht, as an assistant professor at the Department of Clinical Immunology.[7]
In 1991, Clevers became a professor and the chair of the Department of Immunology at the University of Utrecht.[7] He moved to the University Medical Center Utrecht in 2002 as a professor in molecular genetics, and started his lab at the Hubrecht Institute for Developmental Biology and Stem Cell Research (Hubrecht Institute).[6] At the same time, he took up the position of Director of the Hubrecht Institute.[7]
In March 2012, Clevers was elected the president of the Royal Netherlands Academy of Arts and Sciences, succeeding Robbert Dijkgraaf.[16][17] His term concluded in 2015, and he started another lab at the Princess Máxima Center ,[7] focusing on childhood cancer,[9] and became the Director Research and Chief Scientific Officer there until 2019.[7]
Clevers left University Medical Center Utrecht and was appointed Professor in Molecular Genetics at the University of Utrecht in 2020.[6]
In 2022, Clevers joined the Swiss healthcare company Roche as its Head of Pharma, Research and Early Development and a member of its Corporate Executive Committee.[18][19] He remains an advisor and guest scientist or visiting researcher to his research groups at the Princess Máxima Center and Hubrecht Institute.[8][9]
Since 2017, Clevers is an investigator at the Oncode Institute in Utrecht.[6][20]
Clevers has served at a number of scientific organizations, including on the Board of Directors of the American Association of Cancer Research (2013-2016),[21] and the Scientific Advisory Board of the Swiss Institute for Experimental Cancer Research at the École Polytechnique Fédérale de Lausanne (2005-2015),[7] the Research Institute of Molecular Pathology in Vienna (2015-2021)[22] and the Francis Crick Institute in London.[23] He is currently on the advisory board of various scientific journals, including The EMBO Journal,[24] Disease Models & Mechanisms,[25], Cell,[26] Cell Stem Cell[27] and EMBO Molecular Medicine.[28] From 2014 to 2022, he was also on the editorial committee of the Annual Review of Cancer Biology.[6]
Outside the academia, Clevers has been a scientific advisor to numerous biotechnology companies.[6] He also co-founded California-based Surrozen[29] in 2016[30] and Shanghai-based D1 Medical Technology[31] in 2019.[32]
Research
Clevers's early career focused on the Wnt signaling pathway.[33] His group identified the TCF1 protein, a member of the TCF gene family and a crucial downstream component of the Wnt signaling pathway, making it central in immune responses, embryonic development and tissue repair.[34] His interest in the gastrointestinal tract began with the discovery that another TCF family member, the TCF4 protein, is required in forming intestinal crypts.[35] Collaborating with Bert Vogelstein, he found that in colon cancer where the APC gene is doubly mutated, TCF family members activate catenin beta-1, which then enhances the expression of many genes that cause cancer transformation,[36] connecting the Wnt signaling pathway with colon cancer.
In 2007, Clevers's group identified a marker for stem cells of the small and large intestines, LGR5, itself also a target of the Wnt signaling pathway.[37] This led to his finding that LGR5 is a stem cell marker in other organs as well, including the stomach[38] and hair follicles.[39]
Building on this discovery, in 2009, his group published a landmark paper, describing for the first time how organoids, which are 3-dimensional in vitro structures that behave anatomically and molecularly like the organ from which they are derived, were generated from adult stem cells, creating organoids of the small intestine.[40] Clevers's group has applied this technology to culturing organoids from other organs, such as the stomach[38] and liver,[41] as well as from various cancer types, including cancer of the breast[42] and the ovaries.[43] This platform has since been applied in personalized medicine, by generating organoids from specific patients to screen for drugs.[44][45] This is not limited to cancer but is applicable to other diseases as well (for example, cystic fibrosis).[46] His current major research interest is in using organoids derived from adult stem cells to study the molecular mechanism of tissue and cancer development.
During the COVID-19 pandemic, Clevers's group modelled the infection of SARS-CoV-2 using lung organoids.[47]
Honours and awards
- Member of the European Molecular Biology Organization (1999)[48]
- Member of the Royal Netherlands Academy of Arts and Sciences (2000)[49]
- Spinoza Prize (2001)[50]
- Louis-Jeantet Prize for Medicine (2004)[51]
- Knight of the Legion of Honour (2005)[6]
- Meyenburg Prize (2008)[52]
- Member of Academia Europaea (2009)[53]
- Ernst Jung Prize for Medicine (2011)[54]
- International Honorary Member of the American Academy of Arts and Sciences (2012)[55]
- William Beaumont Prize (2012)[56]
- Dr A.H. Heineken Prize for Medicine (2012)[57]
- Knight of the Order of the Netherlands Lion (2012)[58]
- Member of Koninklijke Hollandsche Maatschappij der Wetenschappen (2012)[59]
- Breakthrough Prize in Life Sciences (2013)[60]
- International Member of the National Academy of Sciences (2014)[61]
- Fellow of the American Association for Cancer Research Academy[62]
- Foreign Associate of the French Academy of Sciences (2015)[63]
- Pour le Mérite (2016)[64][65]
- Körber European Science Prize (2016)[66]
- Knight Commander's Cross of the Order of Merit of the Federal Republic of Germany (2018)[67]
- Foreign Member of the Royal Society (2019)[68]
- Honorary Fellow of the Royal Society of Edinburgh (2019)[69]
- Keio Medical Science Prize (2019)[70]
References
- ^ a b "Mentoring the Next Generation: Hans Clevers". Cell Stem Cell. 23 (6): 784–786. 2018. doi:10.1016/j.stem.2018.11.004. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ a b c d "2016 – Johannes C. Clevers". Ilse & Helmut Wachter Foundation, Medical University of Innsbruck. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ a b c "Prof.dr. J.C. Clevers" (in Dutch). Utrecht University. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ a b "Prof. dr. J.C. (Hans) Clevers" (in Dutch). University Medical Center Utrecht. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ Clevers, Hans (1 October 2021). "The development of organoids for cancer research: an ode to the scientific method". Cancer World. Archived from the original on 29 June 2022. Retrieved 29 June 2022.
- ^ a b c d e f g h i j "CURRICULUM VITAE" (PDF). University of Utrecht. Archived from the original (PDF) on 23 June 2022. Retrieved 23 June 2022.
- ^ a b c d e f g h i "Prof. Dr. Hans Clevers". Roche. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ a b "Clevers: Adult stem cell-based organoids". University of Utrecht. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ a b c "Clevers group". Princess Máxima Center . Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ a b c d "A gutsy approach to stem cells and signalling: an interview with Hans Clevers". Disease Models & Mechanisms. 6 (5): 1053–1056. 2013. doi:10.1242/dmm.013367. PMC 3759325. PMID 24046385. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ "Hans Clevers on Becoming a Scientist". Cold Spring Harbor Laboratory. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ Menkhorst, Roos (22 June 2013). "Ik leerde het belang van vertrouwen in mezelf". Trouw (in Dutch). Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ "Hans Clevers". Breakthrough Prize in Life Sciences. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ "Hans Clevers". Hubrecht Institute for Developmental Biology and Stem Cell Research. Archived from the original on 31 December 2011. Retrieved 15 March 2012.
- ^ "Distinguished Lecture: Hans Clevers - "Gut Stem Cells, Organoids, and Precision Medicine". Columbia University. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ van Aartsen, Carina (26 March 2012). "Hans Clevers volgt KNAW-president Robbert Dijkgraaf op". Zorgvisie (in Dutch). Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ "President: Hans Clevers". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 6 August 2013.
{{cite web}}
:|archive-date=
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timestamp mismatch; 1 February 2013 suggested (help) - ^ "New challenge for Hans Clevers at Roche". Hubrecht Institute for Developmental Biology and Stem Cell Research. 1 February 2022. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ "Changes to the Roche Board of Directors and the Corporate Executive Committee" (Press release). Basel: Roche. 1 February 2022. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ "Hans Clevers Group". Oncode Institute. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ "American Association for Cancer Research Councilors and Directors" (PDF). American Association of Cancer Research. Archived from the original (PDF) on 24 June 2022. Retrieved 24 June 2022.
- ^ "Former SAB Members". Research Institute of Molecular Pathology. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ "Hans Clevers". Francis Crick Institute. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ "Advisory Board Biographies". The EMBO Journal. Archived from the original on 27 June 2022. Retrieved 24 June 2022.
- ^ "Editors and Board". Disease Models & Mechanisms. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ "Staff and advisory board". Cell. Archived from the original on 27 June 2022. Retrieved 24 June 2022.
- ^ "Advisory board". Cell Stem Cell. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ "Advisory Board Biographies". EMBO Molecular Medicine. Archived from the original on 27 June 2022. Retrieved 24 June 2022.
- ^ "Hans Clevers, MD, PhD". Surrozen. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ "Surrozen to Present at Cowen and Company 40th Annual Health Care Conference". Surrozen (Press release). South San Francisco, California: Surrozen. 2 March 2020. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ "创始团队" (in Chinese). D1 Medical Technology. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ "丹望医疗完成数千万元天使轮融资,凯风创投领投". Sina (in Chinese). 8 February 2021. Archived from the original on 24 June 2022. Retrieved 24 June 2022.
- ^ Sinha, Gunjan (2017). "The organoid architect". 357 (6353): 746–749. doi:10.1126/science.357.6353.746. PMID 28839056. Archived from the original on 28 June 2022. Retrieved 28 June 2022.
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: Cite journal requires|journal=
(help) - ^ van de Wetering, Marc; Oosterwegel, Mariette; Dooijes, Dennis; Clevers, Hans (1991). "Identification and cloning of TCF-1, a T cell-specific transcription factor containing a sequence-specific HMG box" (PDF). The EMBO Journal. 10 (1): 123–132. doi:10.1002/j.1460-2075.1991.tb07928.x. PMC 452620. PMID 1989880. Archived from the original (PDF) on 23 June 2022. Retrieved 23 June 2022.
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timestamp mismatch; 28 June 2022 suggested (help) - ^ Korinek, Vladimir; Barker, Nick; Moerer, Petra; van Donselaar, Elly; Huls, Gerwin; Peters, Peter J.; Clevers, Hans (1997). "Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4". Nature Genetics. 19 (4): 379–383. doi:10.1038/1270. PMID 9697701. Retrieved 28 June 2022.
- ^ Korinek, Vladimir; Barker, Nick; Morin, Patrice J.; van Wichen, Dick; de Weger, Roel; Kinzler, Kenneth W.; Vogelstein, Bert; Clevers, Hans (1997). "Constitutive Transcriptional Activation by a β-Catenin-Tcf Complex in APC−/− Colon Carcinoma". Science. 275 (5307): 1784–1787. doi:10.1126/science.275.5307.1784. PMID 9065401. Retrieved 28 June 2022.
- ^ Barker, Nick; van Es, Johan H.; Kuipers, Jeroen; Kujala, Pekka; van den Born, Maaike; Cozijnsen, Miranda; Haegebarth, Andrea; Korving, Jeroen; Begthel, Harry; Peters, Peter J.; Clevers, Hans (2007). "Identification of stem cells in small intestine and colon by marker gene Lgr5". Nature. 449 (7165): 1003–1007. doi:10.1038/nature06196. PMID 17934449. Retrieved 23 June 2022.
- ^ a b Barker, Nick; Huch, Meritxell; Kujala, Pekka; van de Wetering, Marc; Snippert, Hugo J.; van Es, Johan H.; Sato, Toshiro; Stange, Daniel E.; Begthel, Harry; van den Born, Maaike; Danenberg, Esther; van den Brink, Stieneke; Korving, Jeroen; Abo, Arie; Peters, Peter J.; Wright, Nick; Poulsom, Richard; Clevers, Hans (2010). "Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro". Cell Stem Cell. 6 (1): 25–36. doi:10.1016/j.stem.2009.11.013. PMID 20085740. Archived from the original on 29 June 2022. Retrieved 29 June 2022.
- ^ Jaks, Viljar; Barker, Nick; Kasper, Maria; van Es, Johan H; Snippert, Hugo J; Clevers, Hans; Toftgård, Rune (2008). "Lgr5 marks cycling, yet long-lived, hair follicle stem cells". Nature Genetics. 40 (11): 1291–1299. doi:10.1038/ng.239. PMID 18849992. Retrieved 23 June 2022.
- ^ Sato, Toshiro; Vries, Robert G.; Snippert, Hugo J.; van de Wetering, Marc; Barker, Nick; Stange, Daniel E.; van Es, Johan H.; Abo, Arie; Kujala, Pekka; Peters, Peter J.; Clevers, Hans (2009). "Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche". Nature. 459 (7244): 262–265. doi:10.1038/nature07935. PMID 19329995. Retrieved 23 June 2022.
- ^ Huch, Meritxell; Dorrell, Craig; Boj, Sylvia F.; van Es, Johan H.; van de Wetering, Marc; Li, Vivian S.W.; Hamer, Karien; Sasaki, Nobuo; Finegold, Milton J.; Haft, Annelise; Grompe, Markus; Clevers, Hans (2013). "In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration". Nature. 494 (7436): 247–250. doi:10.1038/nature11826. PMC 3634804. PMID 23354049. Archived from the original on 29 June 2022. Retrieved 29 June 2022.
- ^ Sachs, Norman; de Ligt, Joep; Kopper, Oded; Gogola, Ewa; Bounova, Gergana; Weeber, Fleur; Vanita Balgobind, Anjali; Wind, Karin; Gracanin, Ana; Begthel, Harry; Korving, Jeroen; van Boxtel, Ruben; Alves Duarte, Alexandra; Lelieveld, Daphne; van Hoeck, Arne; Ernst, Robert Frans; Blokzijl, Francis; Nijman, Isaac Johannes; Hoogstraat, Marlous; van de Ven, Marieke; Egan, David Anthony; Zinzalla, Vittoria; Moll, Jurgen; Fernandez Boj, Sylvia; Voest, Emile Eugene; Wessels, Lodewyk; van Diest, Paul Joannes; Rottenberg, Sven; Vries, Robert Gerhardus Jacob; Cuppen, Edwin; Clevers, Hans (2018). "A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity". Cell. 172 (1–2): 373–386. doi:10.1016/j.cell.2017.11.010. PMID 29224780. Archived from the original on 29 June 2022. Retrieved 29 June 2022.
- ^ Kopper, Oded; de Witte, Chris J.; Lõhmussaar, Kadi; Valle-Inclan, Jose Espejo; Hami, Nizar; Kester, Lennart; Vanita Balgobind, Anjali; Korving, Jeroen; Proost, Natalie; Begthel, Harry; van Wijk, Lise M; Aristín Revilla, Sonia; Theeuwsen, Rebecca; van de Ven, Marieke; van Roosmalen, Markus J; Ponsioen, Bas; Ho, Victor W. H.; Neel, Benjamin G.; Bosse, Tjalling; Gaarenstroom, Katja N.; Vrieling, Harry; Vreeswijk, Maaike P. G.; van Diest, Paul J.; Witteveen, Petronella O.; Jonges, Trudy; Bos, Johannes L.; van Oudenaarden, Alexander; Zweemer, Ronald P.; Snippert, Hugo J. G.; Kloosterman 14 , Hans Clevers, Wigard P. (2019). "An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity". Nature Medicine. 25 (5): 838–849. doi:10.1038/s41591-019-0422-6. PMID 31011202. Retrieved 29 June 2022.
{{cite journal}}
: CS1 maint: numeric names: authors list (link) - ^ Bartfeld, Sina (2021). "Realizing the potential of organoids—an interview with Hans Clevers". Journal of Molecular Medicine. 99 (4): 443–447. doi:10.1007/s00109-020-02025-3. PMC 8026466. PMID 33464358. Archived from the original on 29 June 2022. Retrieved 29 June 2022.
- ^ Bender, Eric (2015). "Q&A: Hans Clevers". Nature. 521 (7551): S15. doi:10.1038/521S15a. PMID 25970453. Archived from the original on 29 June 2022. Retrieved 29 June 2022.
- ^ Saini, Angela (2016). "Cystic Fibrosis Patients Benefit from Mini Guts" (PDF). Cell Stem Cell. 19 (4): 425–427. doi:10.1016/j.stem.2016.09.001. Archived from the original (PDF) on 26 June 2022. Retrieved 26 June 2022.
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timestamp mismatch; 25 June 2022 suggested (help) - ^ Lamers, Mart M; van der Vaart, Jelte; Knoops, Kèvin; Riesebosch, Samra; Breugem, Tim I; Mykytyn, Anna Z; Beumer, Joep; Schipper, Debby; Bezstarosti, Karel; Koopman, Charlotte D; Groen, Nathalie; Ravelli, Raimond B G; Duimel, Hans Q; Demmers, Jeroen A A; Verjans, Georges M G M; Koopmans, Marion P G; Muraro, Mauro J; Peters, Peter J; Clevers, Hans; Haagmans, Bart L (2021). "An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells". The EMBO Journal. 40 (5): e105912. doi:10.15252/embj.2020105912. PMC 7883112. PMID 33283287. Archived from the original on 29 June 2022. Retrieved 29 June 2022.
- ^ "Hans C. Clevers". European Molecular Biology Organization. Archived from the original on 26 June 2022. Retrieved 26 June 2022.
- ^ "Hans Clevers". Royal Netherlands Academy of Arts and Sciences. Archived from the original on 16 August 2019. Retrieved 16 August 2019.
- ^ "NWO Spinoza Prize 2001". Dutch Research Council. Archived from the original on 31 October 2020. Retrieved 31 October 2020.
- ^ "Professor Hans CLEVERS". Louis-Jeantet Foundation. Archived from the original on 26 June 2022. Retrieved 26 June 2022.
- ^ "Die Preisträger" (in German). Meyenburg Foundation. Archived from the original on 26 June 2022. Retrieved 26 June 2022.
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timestamp mismatch; 4 April 2022 suggested (help) - ^ "Hans Clevers". Academia Europaea. Archived from the original on 26 June 2022. Retrieved 26 June 2022.
- ^ "Laureates 1976 to 2021". Ernst Jung Foundation. Archived from the original on 27 June 2022. Retrieved 27 June 2022.
- ^ "Johannes Carolus Clevers". American Academy of Arts and Sciences. Archived from the original on 27 June 2022.
- ^ "William Beaumont Prize in Gastroenterology". American Gastroenterological Association. Archived from the original on 27 June 2022. Retrieved 27 June 2022.
- ^ "Hans Clevers". Heineken Prizes. Archived from the original on 27 June 2022. Retrieved 27 June 2022.
- ^ "Koninklijke onderscheidingen 2012" (in Dutch). Utrecht University. Archived from the original on 9 May 2015. Retrieved 9 May 2015.
- ^ "NIEUWE LEDEN" (PDF). Jaarverslag 2012. Koninklijke Hollandsche Maatschappij der Wetenschappen. Archived from the original (PDF) on 27 June 2022. Retrieved 27 June 2022.
- ^ "Hans Clevers". Breakthrough Prize in Life Sciences. Archived from the original on 16 April 2022. Retrieved 16 April 2022.
{{cite web}}
:|archive-date=
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timestamp mismatch; 14 February 2022 suggested (help) - ^ "Hans Clevers". National Academy of Sciences. Archived from the original on 27 June 2022. Retrieved 27 June 2022.
- ^ "Hans Clevers, MD, PhD". American Association for Cancer Research. Archived from the original on 27 June 2022. Retrieved 27 June 2022.
- ^ "Hans Clevers" (in French). French Academy of Sciences. Archived from the original on 28 June 2022. Retrieved 27 June 2022.
- ^ "Hans Clevers" (in German). Pour le Mérite für Wissenschaften und Künste. Archived from the original on 28 June 2022. Retrieved 27 June 2022.
- ^ "Hans CLEVERS" (PDF). Pour le Mérite für Wissenschaften und Künste. Archived from the original (PDF) on 27 June 2022. Retrieved 27 June 2022.
- ^ "Hans Clevers (2016): Replacement organs from a petri dish". Körber Foundation. Archived from the original on 27 June 2022. Retrieved 27 June 2022.
- ^ "German award for Hans Clevers". Princess Máxima Center. 2 March 2018. Archived from the original on 27 June 2022. Retrieved 27 June 2022.
- ^ "Hans Clevers". Royal Society. Archived from the original on 23 June 2022. Retrieved 23 June 2022.
- ^ "Professor Johannes Carolus Clevers ForMemRS, HonFRSE". Royal Society of Edinburgh. Archived from the original on 1 August 2020. Retrieved 1 August 2020.
- ^ "Hans C. Clevers" (in Japanese). Keio University. Archived from the original on 27 June 2022. Retrieved 27 June 2022.
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:|archive-date=
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timestamp mismatch; 15 May 2020 suggested (help)
External links
- Hans Clevers publications indexed by Google Scholar
- 1957 births
- Living people
- Dutch geneticists
- Dutch immunologists
- Fellows of the AACR Academy
- Fellows of the American Academy of Arts and Sciences
- Foreign associates of the National Academy of Sciences
- Foreign Members of the Royal Society
- Honorary Fellows of the Royal Society of Edinburgh
- Knights Commander of the Order of Merit of the Federal Republic of Germany
- Knights of the Order of the Netherlands Lion
- Members of Academia Europaea
- Members of the European Molecular Biology Organization
- Members of the French Academy of Sciences
- Members of the Royal Netherlands Academy of Arts and Sciences
- Recipients of the Pour le Mérite (civil class)
- People from Eindhoven
- Spinoza Prize winners
- Stem cell researchers
- Utrecht University alumni
- Utrecht University faculty
- Winners of the Heineken Prize
- Recipients of the Legion of Honour
- Members of the Koninklijke Hollandsche Maatschappij der Wetenschappen