Ambucetamide: Difference between revisions

Ambucetamide
Clinical data
ATC code	none;
Identifiers
	IUPAC name 2-(dibutylamino)-2-(4-methoxyphenyl)acetamide;
CAS Number	519-88-0 ;
PubChem CID	10616;
ChemSpider	10171 ;
UNII	131B408RZI;
ChEMBL	ChEMBL2104638 ;
CompTox Dashboard (EPA)	DTXSID4057760 ;
ECHA InfoCard	100.007.527
Chemical and physical data
Formula	C17H28N2O2
Molar mass	292.423 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N)C(c1ccc(OC)cc1)N(CCCC)CCCC;
	InChI InChI=1S/C17H28N2O2/c1-4-6-12-19(13-7-5-2)16(17(18)20)14-8-10-15(21-3)11-9-14/h8-11,16H,4-7,12-13H2,1-3H3,(H2,18,20) ; Key:WUSAVCGXMSWMQM-UHFFFAOYSA-N ;
	(what is this?) (verify)

Browse history interactively

← Previous edit

Content deleted Content added

VisualWikitext

Inline

Latest revision as of 19:59, 23 September 2024

Ambucetamide is an antispasmodic found to be particularly effective for the relief of menstrual pain. It was discovered in 1953 by Paul Janssen.

References

Hoekstra JB, Fisher DS, Cull KM, Tisch DE, Dickison HL (September 1957). "Studies with a uterine antispasmodic, ambucetamide". Journal of the American Pharmaceutical Association. 46 (9): 564–568. doi:10.1002/jps.3030460915. PMID 13491452.
Pickles VR, Clitheroe HJ (March 1960). "The effects of ambucetamide on human myometrial and other preparations, and its antagonism to the menstrual stimulant". British Journal of Pharmacology and Chemotherapy. 15 (1): 128–30. doi:10.1111/j.1476-5381.1960.tb01220.x. PMC 1481989. PMID 14432761.

This drug article relating to the genito-urinary system is a stub. You can help Wikipedia by expanding it.

@@ Line 1: / Line 1: @@
+{{Short description|Chemical compound}}
-{{drugbox |
+{{Drugbox
-| IUPAC_name        = 2-(dibutylamino)-2-(4-methoxyphenyl)acetamide
+| Verifiedfields = changed
-| image             = Ambucetamide.svg
+| verifiedrevid = 447616955
-| CAS_number        = 519-88-0
+| IUPAC_name = 2-(dibutylamino)-2-(4-methoxyphenyl)acetamide
-| ATC_prefix        =
+| image = Ambucetamide.svg
-| ATC_suffix        =
-| PubChem           = 10616
+<!--Clinical data-->
-| DrugBank          =
-| chemical_formula  =
+| tradename =
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
-| C=17|H=28|N=2|O=2
+| pregnancy_US = <!-- A / B            / C / D / X -->
-| molecular_weight  = 292.417 g·mol<sup>−1</sup>
+| pregnancy_category =
-| bioavailability   =
+| legal_AU = <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
-| protein_bound     =
+| legal_CA = <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
-| metabolism        =
+| legal_UK = <!-- GSL         / P       / POM / CD / Class A, B, C -->
-| elimination_half-life =
+| legal_US = <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
-| excretion         =
+| legal_status =
-| smiles = CCCCN(CCCC)C(C1=CC=C(C=C1)OC)C(=O)N
+| routes_of_administration =
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
+<!--Pharmacokinetic data-->
-| pregnancy_category=
+| bioavailability =
-| legal_AU          =  <!-- Unscheduled / S2 / S3 / S4 / S5 / S6 / S7 / S8 / S9 -->
+| protein_bound =
-| legal_CA          =  <!--             / Schedule I, II, III, IV, V, VI, VII, VIII -->
+| metabolism =
-| legal_UK          =  <!-- GSL         / P       / POM / CD / Class A, B, C -->
+| elimination_half-life =
-| legal_US          =  <!-- OTC                   / Rx-only  / Schedule I, II, III, IV, V -->
+| excretion =
-| legal_status      =
-| routes_of_administration =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
+| CAS_number = 519-88-0
+| ATC_prefix = none
+| ATC_suffix =
+| PubChem = 10616
+| ChEMBL_Ref = {{ebicite|changed|EBI}}
+| ChEMBL = 2104638
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank =
+| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
+| ChemSpiderID = 10171
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = 131B408RZI
+<!--Chemical data-->
+| chemical_formula =
+| C=17 | H=28 | N=2 | O=2
+| smiles = O=C(N)C(c1ccc(OC)cc1)N(CCCC)CCCC
+| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChI = 1S/C17H28N2O2/c1-4-6-12-19(13-7-5-2)16(17(18)20)14-8-10-15(21-3)11-9-14/h8-11,16H,4-7,12-13H2,1-3H3,(H2,18,20)
+| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
+| StdInChIKey = WUSAVCGXMSWMQM-UHFFFAOYSA-N
 }}
-'''Ambucetamide''' is an [[antispasmodic]] found to be particularly effective for the relief of [[menstrual]] pain.  It was discovered in 1953 by [[Paul Janssen]].
+'''Ambucetamide''' is an [[antispasmodic]] found to be particularly effective for the relief of [[menstrual pain]].  It was discovered in 1953 by [[Paul Janssen]].
 ==References==
+{{Reflist}}
-* Hoekstra JB, Fisher DS, Cull KM, Tisch DE, Dickison HL., Studies with a uterine antispasmodic, ambucetamide, J Am Pharm Assoc Am Pharm Assoc (Baltim). 1957 Sep;46(9):564-8.
+* {{cite journal | vauthors = Hoekstra JB, Fisher DS, Cull KM, Tisch DE, Dickison HL | title = Studies with a uterine antispasmodic, ambucetamide | journal = Journal of the American Pharmaceutical Association | volume = 46 | issue = 9 | pages = 564–568 | date = September 1957 | pmid = 13491452 | doi = 10.1002/jps.3030460915 }}
-* Pickles VR, Clitheroe HJ., The effects of ambucetamide on human myometrial and other preparations, and its antagonism to the menstrual stimulant, Br J Pharmacol Chemother. 1960 Mar;15:128-30.
+* {{cite journal | vauthors = Pickles VR, Clitheroe HJ | title = The effects of ambucetamide on human myometrial and other preparations, and its antagonism to the menstrual stimulant | journal = British Journal of Pharmacology and Chemotherapy | volume = 15 | issue = 1| pages = 128–30 | date = March 1960 | pmid = 14432761 | pmc = 1481989 | doi = 10.1111/j.1476-5381.1960.tb01220.x | url = }}
+[[Category:Antispasmodics]]
+[[Category:Acetamides]]
+[[Category:4-Methoxyphenyl compounds]]
+[[Category:Janssen Pharmaceutica]]
+[[Category:Belgian inventions]]
+{{genito-urinary-drug-stub}}
-[[Category:Drugs]]
-{{drug-stub}}