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| ⚫ | '''Ateronon''' is a [[ |
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| ⚫ | '''Ateronon''' is a [[nutraceutical]] composed of lactolycopene, a combination of [[lycopene]] from tomato oleoresin and a [[whey protein]] matrix which increases the absorption / [[bioavailability]] of lycopene.<ref name=Foot01>{{cite journal |vauthors=Richelle M, Bortlik K, Liardet S, etal |title=A food-based formulation provides lycopene with the same bioavailability to humans as that from tomato paste |journal=J. Nutr. |volume=132 |issue=3 |pages=404–8 |date=March 2002 |pmid=11880563 |type=Clinical trial|doi=10.1093/jn/132.3.404 |doi-access=free }}</ref><ref name=Foot02>{{cite journal |vauthors=Blume-Peytavi U, Rolland A, Darvin ME, etal |title=Cutaneous lycopene and beta-carotene levels measured by resonance Raman spectroscopy: high reliability and sensitivity to oral lactolycopene deprivation and supplementation |journal=Eur J Pharm Biopharm |volume=73 |issue=1 |pages=187–94 |date=September 2009 |pmid=19442725 |doi=10.1016/j.ejpb.2009.04.017 |type=Clinical trial}}</ref> |
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There is no good evidence taking ateronon has more benefit than eating tomato food products, or even that it provides any health benefit at all.<ref name=nhs>{{cite web |publisher=[[NHS Choices]] |url=http://www.nhs.uk/news/2009/06June/Pages/Tomatopillforheartdisease.aspx |date=3 June 2009 |accessdate=December 2014 |title=Tomato pill for heart disease?}}</ref> |
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A report containing data on Ateronon was presented at the British Cardiovascular Society Conference in June 2014.<ref>{{cite web|title=Ateronon briefing sponsored symposium at the British Cardiovascular Society Annual Conference|url=https://thetomatopill.com/pdf/bcs-report.pdf|accessdate=2014-06-03|date=June 2014}}</ref> |
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== Studies == |
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LactoLycopene has been used in numerous studies focused on lycopene bioavailability. A University of Cambridge study shows that lycopene levels in the blood rose between 60% and 100% within two months for people taking LactoLycopene, while another study at Boston's Brigham & Women's Hospital, run by Harvard Medical School, found that it increased average blood levels of lycopene at both six and 12 months.<ref name=Foot04>{{cite journal |vauthors=Karppi J, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S |s2cid=29290243 |title=Serum lycopene decreases the risk of stroke in men. |journal= Neurology|volume=73 |issue=1 |pages=187–94 |date=September 2009 |pmid= 23045517|doi=10.1212/WNL.0b013e31826e26a6 |type=Clinical trial}}</ref> |
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It has also been used to investigate the effects of lycopene on heart function <ref name=Foot05>{{cite journal |vauthors=Gajendragadkar PR, Hubsch A, Mäki-Petäjä KM, Serg M, Wilkinson IB, Cheriyan J |title=Effects of Oral Lycopene Supplementation on Vascular Function in Patients with Cardiovascular Disease and Healthy Volunteers: A Randomised Controlled Trial |journal=PLOS ONE |volume=9 |issue=6 |pages=e99070 |date=June 2014 |doi=10.1371/journal.pone.0099070 |pmid=24911964 |pmc=4049604 |type=Clinical trial|bibcode=2014PLoSO...999070G |doi-access=free }}</ref><ref name=Foot06>{{cite journal |vauthors=Karppi J, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S |s2cid=29290243 |title=Serum lycopene decreases the risk of stroke in men |journal=Neurology |volume=79 |issue=15 |pages=1540–1547 |date=October 2012 |doi=10.1212/WNL.0b013e31826e26a6 |pmid=23045517 |type=Clinical trial}}</ref> and male fertility. |
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A study at the Cleveland Clinic found that lycopene can boost sperm quality by up to 70 per cent,<ref name=Foot07>{{cite journal |vauthors=Durairajanayagam D, Agarwal A, Ong C, Prashast P |title=Lycopene and male infertility |journal= Asian Journal of Andrology|volume=16 |issue=3 |pages=420–425 |date=March 2014 |pmid=24675655 |pmc=4023371 |doi=10.4103/1008-682X.126384 |type=Clinical trial |doi-access=free }}</ref> while a team of researchers at the University of Sheffield found that LactoLycopene supplementation significantly increases the percentage of fast progressive sperm as well as normal and healthy sperm forms.<ref name=Foot08>{{cite journal |vauthors=Williams EA, Parker M, Robinson A et al |title=A randomized placebo-controlled trial to investigate the effect of lactolycopene on semen quality in healthy males |journal= European Journal of Nutrition|date=September 2019 |volume=59 |issue=2 |pages=825–833 |doi=10.1007/s00394-019-02091-5 |pmid=31591650 |pmc=7058571 |type=Clinical trial|doi-access=free }}</ref> |
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== History == |
== History == |
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Ateronon was developed by Cambridge Theranostics Ltd |
Ateronon was developed by Cambridge Theranostics Ltd, UK, and launched in 2009.<ref>{{cite news|title=Tomato pill 'beats heart disease'|url=http://news.bbc.co.uk/2/hi/health/8076556.stm|accessdate=2017-02-12|work=BBC News|date=1 June 2009}}</ref> The patent is currently held by its successor company, FutureYou Cambridge. |
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== References == |
== References == |
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[[Category:Dietary supplements]] |
[[Category:Dietary supplements]] |
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Latest revision as of 22:17, 2 December 2023
Ateronon is a nutraceutical composed of lactolycopene, a combination of lycopene from tomato oleoresin and a whey protein matrix which increases the absorption / bioavailability of lycopene.[1][2]
A report containing data on Ateronon was presented at the British Cardiovascular Society Conference in June 2014.[3]
Studies
[edit]LactoLycopene has been used in numerous studies focused on lycopene bioavailability. A University of Cambridge study shows that lycopene levels in the blood rose between 60% and 100% within two months for people taking LactoLycopene, while another study at Boston's Brigham & Women's Hospital, run by Harvard Medical School, found that it increased average blood levels of lycopene at both six and 12 months.[4]
It has also been used to investigate the effects of lycopene on heart function [5][6] and male fertility.
A study at the Cleveland Clinic found that lycopene can boost sperm quality by up to 70 per cent,[7] while a team of researchers at the University of Sheffield found that LactoLycopene supplementation significantly increases the percentage of fast progressive sperm as well as normal and healthy sperm forms.[8]
History
[edit]Ateronon was developed by Cambridge Theranostics Ltd, UK, and launched in 2009.[9] The patent is currently held by its successor company, FutureYou Cambridge.
References
[edit]- ^ Richelle M, Bortlik K, Liardet S, et al. (March 2002). "A food-based formulation provides lycopene with the same bioavailability to humans as that from tomato paste". J. Nutr. (Clinical trial). 132 (3): 404–8. doi:10.1093/jn/132.3.404. PMID 11880563.
- ^ Blume-Peytavi U, Rolland A, Darvin ME, et al. (September 2009). "Cutaneous lycopene and beta-carotene levels measured by resonance Raman spectroscopy: high reliability and sensitivity to oral lactolycopene deprivation and supplementation". Eur J Pharm Biopharm (Clinical trial). 73 (1): 187–94. doi:10.1016/j.ejpb.2009.04.017. PMID 19442725.
- ^ "Ateronon briefing sponsored symposium at the British Cardiovascular Society Annual Conference" (PDF). June 2014. Retrieved 2014-06-03.
- ^ Karppi J, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S (September 2009). "Serum lycopene decreases the risk of stroke in men". Neurology (Clinical trial). 73 (1): 187–94. doi:10.1212/WNL.0b013e31826e26a6. PMID 23045517. S2CID 29290243.
- ^ Gajendragadkar PR, Hubsch A, Mäki-Petäjä KM, Serg M, Wilkinson IB, Cheriyan J (June 2014). "Effects of Oral Lycopene Supplementation on Vascular Function in Patients with Cardiovascular Disease and Healthy Volunteers: A Randomised Controlled Trial". PLOS ONE (Clinical trial). 9 (6): e99070. Bibcode:2014PLoSO...999070G. doi:10.1371/journal.pone.0099070. PMC 4049604. PMID 24911964.
- ^ Karppi J, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S (October 2012). "Serum lycopene decreases the risk of stroke in men". Neurology (Clinical trial). 79 (15): 1540–1547. doi:10.1212/WNL.0b013e31826e26a6. PMID 23045517. S2CID 29290243.
- ^ Durairajanayagam D, Agarwal A, Ong C, Prashast P (March 2014). "Lycopene and male infertility". Asian Journal of Andrology (Clinical trial). 16 (3): 420–425. doi:10.4103/1008-682X.126384. PMC 4023371. PMID 24675655.
- ^ Williams EA, Parker M, Robinson A, et al. (September 2019). "A randomized placebo-controlled trial to investigate the effect of lactolycopene on semen quality in healthy males". European Journal of Nutrition (Clinical trial). 59 (2): 825–833. doi:10.1007/s00394-019-02091-5. PMC 7058571. PMID 31591650.
- ^ "Tomato pill 'beats heart disease'". BBC News. 1 June 2009. Retrieved 2017-02-12.
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