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Importing Wikidata short description: Protein-coding gene in the species Homo sapiens (shortdescs-in-category) |
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{{Short description|Protein-coding gene in the species Homo sapiens}} |
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'''Sodium channel subunit beta-2''' is a [[protein]] that in humans is encoded by the ''SCN2B'' [[gene]].<ref name="pmid10198179">{{cite journal | vauthors = Plummer NW, Meisler MH | title = Evolution and diversity of mammalian sodium channel genes | journal = Genomics | volume = 57 | issue = 2 | pages = 323–31 |date=May 1999 | pmid = 10198179 | doi = 10.1006/geno.1998.5735 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SCN2B sodium channel, voltage-gated, type II, beta| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6327}}</ref> |
'''Sodium channel subunit beta-2''' is a [[protein]] that in humans is encoded by the ''SCN2B'' [[gene]].<ref name="pmid10198179">{{cite journal | vauthors = Plummer NW, Meisler MH | title = Evolution and diversity of mammalian sodium channel genes | journal = Genomics | volume = 57 | issue = 2 | pages = 323–31 |date=May 1999 | pmid = 10198179 | doi = 10.1006/geno.1998.5735 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SCN2B sodium channel, voltage-gated, type II, beta| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6327}}</ref> |
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Latest revision as of 00:48, 4 March 2023
Sodium channel subunit beta-2 is a protein that in humans is encoded by the SCN2B gene.[5][6]
See also
[edit]References
[edit]- ^ a b c GRCh38: Ensembl release 89: ENSG00000149575 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000070304 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Plummer NW, Meisler MH (May 1999). "Evolution and diversity of mammalian sodium channel genes". Genomics. 57 (2): 323–31. doi:10.1006/geno.1998.5735. PMID 10198179.
- ^ "Entrez Gene: SCN2B sodium channel, voltage-gated, type II, beta".
Further reading
[edit]- Hartshorne RP, Catterall WA (1984). "The sodium channel from rat brain. Purification and subunit composition". J. Biol. Chem. 259 (3): 1667–75. doi:10.1016/S0021-9258(17)43460-0. PMID 6319405.
- Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence" (PDF). Nature. 377 (6547 Suppl): 3–174. PMID 7566098.
- Isom LL, Ragsdale DS, De Jongh KS, et al. (1996). "Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif". Cell. 83 (3): 433–42. doi:10.1016/0092-8674(95)90121-3. PMID 8521473. S2CID 13998841.
- Eubanks J, Srinivasan J, Dinulos MB, et al. (1997). "Structure and chromosomal localization of the beta2 subunit of the human brain sodium channel". NeuroReport. 8 (12): 2775–9. doi:10.1097/00001756-199708180-00025. PMID 9295116. S2CID 21051920.
- Bolino A, Seri M, Caroli F, et al. (1999). "Exclusion of the SCN2B gene as candidate for CMT4B". Eur. J. Hum. Genet. 6 (6): 629–34. doi:10.1038/sj.ejhg.5200220. PMID 9887383.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Kim DY, Ingano LA, Carey BW, et al. (2005). "Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration". J. Biol. Chem. 280 (24): 23251–61. doi:10.1074/jbc.M412938200. PMID 15833746.
External links
[edit]- SCN2B+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
- Overview of all the structural information available in the PDB for UniProt: O60939 (Sodium channel subunit beta-2) at the PDBe-KB.
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