Adosopine: Difference between revisions
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correct IUPAC name |
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| PIN = ''N''-(5-Methyl-6,11-dioxo-6,11-dihydro-5''H''-dibenzo[''b'',''e'']azepin-10-yl)acetamide |
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| OtherNames = Adosupine |
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| CASNo = 88124-26-9 |
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| PubChem = 65661 |
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| ChemSpiderID = 59096 |
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| ChEMBL = 2103994 |
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| UNII = OKB1O47Q6F |
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| InChI = 1/C17H14N2O3/c1-10(20)18-13-8-5-7-12-15(13)16(21)11-6-3-4-9-14(11)19(2)17(12)22/h3-9H,1-2H3,(H,18,20) |
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| InChIKey = KLSKLNWJEDXFSD-UHFFFAOYAV |
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| Appearance = |
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| StdInChI = 1S/C17H14N2O3/c1-10(20)18-13-8-5-7-12-15(13)16(21)11-6-3-4-9-14(11)19(2)17(12)22/h3-9H,1-2H3,(H,18,20) |
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| StdInChIKey = KLSKLNWJEDXFSD-UHFFFAOYSA-N |
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| SMILES =CC(=O)NC1=CC=CC2=C1C(=O)C3=CC=CC=C3N(C2=O)C }} |
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| C=17 | H=14 | N=2 | O=3 |
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'''Adosopine''' is a [[dibenzoazepine]] [[drug]] that has been studied for the treatment of [[urinary incontinence]].<ref>{{cite journal|pmid=8169779|year=1994|last1=Perico|first1=A|last2=Triolo|first2=A|last3=Viti|first3=G|last4=Mannucci|first4=C|last5=Caviglioli|first5=G|last6=Cocchini|first6=A|last7=Pestellini|first7=V|last8=Paoli|first8=P|last9=Dapporto|first9=P|title=Synthesis, characterization, and analytical studies of adosupine, a potential new drug for urinary incontinence|volume=83|issue=2|pages=137–42|journal=Journal of Pharmaceutical Sciences|doi=10.1002/jps.2600830206}}</ref><ref>{{cite journal|pmid=1618966|year=1992|last1=d'Aranno|first1=V|last2=Mancinelli|first2=A|last3=Manzini|first3=S|title=Determination of the tricyclic compound adosupine and its three metabolites in plasma and brain of rat using high-performance liquid chromatography|volume=574|issue=2|pages=319–25|journal=Journal of Chromatography|doi=10.1016/0378-4347(92)80046-s}}</ref> |
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Adosupine is a bio-active tricyclic compound. |
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==References== |
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{{reflist}} |
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[http://www.ncbi.nlm.nih.gov/pubmed/1618966 Determination of the tricyclic compound adosupine and its three metabolites in plasma and brain of rat using high-performance liquid chromatography] |
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[[Category:Dibenzazepines]] |
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{{organic-chem-stub}} |
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{{genito-urinary-drug-stub}} |
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Latest revision as of 15:50, 23 April 2021
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| Names | |
|---|---|
| Preferred IUPAC name
N-(5-Methyl-6,11-dioxo-6,11-dihydro-5H-dibenzo[b,e]azepin-10-yl)acetamide | |
| Other names
Adosupine
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| Identifiers | |
3D model (JSmol)
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| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.081.230 |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C17H14N2O3 | |
| Molar mass | 294.310 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Adosopine is a dibenzoazepine drug that has been studied for the treatment of urinary incontinence.[1][2]
References
[edit]- ^ Perico, A; Triolo, A; Viti, G; Mannucci, C; Caviglioli, G; Cocchini, A; Pestellini, V; Paoli, P; Dapporto, P (1994). "Synthesis, characterization, and analytical studies of adosupine, a potential new drug for urinary incontinence". Journal of Pharmaceutical Sciences. 83 (2): 137–42. doi:10.1002/jps.2600830206. PMID 8169779.
- ^ d'Aranno, V; Mancinelli, A; Manzini, S (1992). "Determination of the tricyclic compound adosupine and its three metabolites in plasma and brain of rat using high-performance liquid chromatography". Journal of Chromatography. 574 (2): 319–25. doi:10.1016/0378-4347(92)80046-s. PMID 1618966.
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