A-84,543

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A-84543 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. It is widely used in scientific research into the structure and function of this receptor subtype and has been the lead compound for the development of a large family of related derivatives.[1][2][3][4][5]

A-84,543
Identifiers
  • 3-(1-methyl-2-(S)-pyrrolidinylmethoxy)pyridine
PubChem CID
ChemSpider
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC11H16N2O
Molar mass192.257 g·mol−1
3D model (JSmol)
  • O(c1c(nccc1)C)C[C@H]2NCCC2
  • InChI=1S/C11H16N2O/c1-9-11(5-3-6-12-9)14-8-10-4-2-7-13-10/h3,5-6,10,13H,2,4,7-8H2,1H3/t10-/m0/s1 checkY
  • Key:YRVIKLBSVVNSHF-JTQLQIEISA-N checkY
  (verify)

References

  1. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 8632405, please use {{cite journal}} with |pmid=8632405 instead.
  2. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 9871663, please use {{cite journal}} with |pmid=9871663 instead.
  3. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 9871663, please use {{cite journal}} with |pmid=9871663 instead.
  4. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 15771418, please use {{cite journal}} with |pmid=15771418 instead.
  5. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 17371077, please use {{cite journal}} with |pmid=17371077 instead.