Sorafenib: Difference between revisions

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replaced the 3D model of the molecule with one based on experimental data (X-ray crystallography)
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==Medical uses==
Sorafenib is indicated as a treatment for advanced [[renal cell carcinoma]] (RCC), unresectable [[hepatocellular carcinoma]]s (HCC) and [[thyroid cancer]].<ref name = MSR>{{cite web|title=Nexavarn95 mask|url=https://accumed.com/n95-mask-for-sale-respirator-safety-face-mask-z1.html (sorafenib) dosing, indications, interactions, adverse effects, and more|work=Medscape Reference|publisher=WebMD|accessdate=26 December 2013|url=http://reference.medscape.com/drug/nexavar-sorafenib-342260#showall}}</ref><ref name = DM>{{cite web|title=Nexavar (sorafenib) tablet, film coated [Bayer HealthCare Pharmaceuticals Inc.]|work=DailyMed|publisher=Bayer HealthCare Pharmaceuticals Inc.|date=November 2013|accessdate=26 December 2013|url=http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b50667e4-5ebc-4968-a646-d605058dbef0}}</ref><ref name = EMC>{{cite web|title=Nexavar 200mg film-coated tablets - Summary of Product Characteristics (SPC) - (eMC)|work=electronic Medicines Compendium|publisher=Bayer plc|date=27 March 2013|accessdate=26 December 2013|url=http://www.medicines.org.uk/emc/medicine/18520/SPC/Nexavar+200mg+film-coated+tablets/}}</ref><ref name = TGA>{{cite web|title=PRODUCT INFORMATION NEXAVAR (sorafenib tosylate)|work=TGA eBusiness Services|publisher=Bayer Australia Ltd|date=12 December 2012|accessdate=26 December 2013|url=https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2010-PI-07403-3|format=PDF}}</ref>
 
===Kidney cancer===