Revision as of 19:23, 29 May 2020 edit Stephaniesb (talk \| contribs) 27 edits →NRTI resistance: Fixed typo (spelling). Tags: Mobile edit Mobile web edit ← Previous edit		Revision as of 07:34, 10 June 2020 edit undo DrVogel (talk \| contribs) Autopatrolled, Extended confirmed users, Rollbackers 28,449 edits →Mechanism: ce Next edit →
Line 5: When HIV infects a cell, reverse transcriptase copies the viral single stranded [[RNA]] genome into a double-stranded viral [[DNA]]. The viral DNA is then integrated into the host chromosomal DNA, which then allows host cellular processes, such as transcription and translation, to reproduce the virus. RTIs block reverse transcriptase's enzymatic function and prevent completion of synthesis of the double-stranded viral DNA, thus preventing HIV from multiplying. A similar process occurs with other types of viruses. The hepatitis B virus, for example, carries its genetic material in the form of DNA, and employs aan RNA-dependent DNA polymerase to replicate. Some of the same compounds used as RTIs can also block HBV replication; when used in this way they are referred to as polymerase inhibitors. ==Types==

Reverse-transcriptase inhibitor: Difference between revisions