Polyvinyl alcohol: Difference between revisions

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PVA-based polymers are used widely in additive manufacturing. For example, 3D printed oral dosage forms demonstrate great potential in the pharmaceutical industry. It is possible to create drug-loaded tablets with modified drug-release characteristics where PVA is used as a binder substance.<ref>{{cite journal |vauthors = Xu X, Zhao J, Wang M, Wang L, Yang J |display-authors=3|title = 3D Printed Polyvinyl Alcohol Tablets with Multiple Release Profiles |journal = Scientific Reports |volume = 9 |issue = 1 |pages = 12487 |date = August 2019 |pmid = 31462744 |pmc = 6713737 |doi = 10.1038/s41598-019-48921-8 }}</ref>
 
Medically, PVA-based [[Microparticle|microparticles]] have received [[Food and Drug Administration|FDA]] [[510k]] approval to be used as [[Embolization|embolisation]] particles to be used for peripheral hypervascular tumors. <ref>{{Cite web |title=Contour™ - Brief Summary |url=https://www.bostonscientific.com/en-US/products/embolization/contour-pva-embolization-particles/contour-prescriptive-information.html |access-date=2023-08-11 |website=www.bostonscientific.com |language=en-us}}</ref> It may also used as the embolic agent in a Uterine Fibroid Embolectomy (UFE).<ref>{{cite web |title = Uterine Fibroid Embolization and Imaging |url = https://emedicine.medscape.com/article/421734-overview#a4 |vauthors = Siskin GP |veditors = Cho KJ |work=Medscape|publisher = WebMD LLC |archive-url=https://web.archive.org/web/20150304224753/https://emedicine.medscape.com/article/421734-overview#a15 |archive-date=2015-03-04}}</ref> In biomedical engineering research, PVA has also been studied for [[cartilage]], [[Orthopedic surgery|orthopaedic]] applications,<ref>{{Cite journal |last=Baker |first=Maribel I. |last2=Walsh |first2=Steven P. |last3=Schwartz |first3=Zvi |last4=Boyan |first4=Barbara D. |date=July 2012-07 |title=A review of polyvinyl alcohol and its uses in cartilage and orthopedic applications |url=https://onlinelibrary.wiley.com/doi/10.1002/jbm.b.32694 |journal=Journal of Biomedical Materials Research Part B: Applied Biomaterials |language=en |volume=100B |issue=5 |pages=1451–1457 |doi=10.1002/jbm.b.32694}}</ref> and potential materials for [[vascular graft]].<ref>{{Cite journal |last=Chaouat |first=Marc |last2=Le Visage |first2=Catherine |last3=Baille |first3=Wilms E. |last4=Escoubet |first4=Brigitte |last5=Chaubet |first5=Frédéric |last6=Mateescu |first6=Mircea Alexandru |last7=Letourneur |first7=Didier |date=2008-10-09 |title=A Novel Cross-linked Poly(vinyl alcohol) (PVA) for Vascular Grafts |url=https://onlinelibrary.wiley.com/doi/10.1002/adfm.200701261 |journal=Advanced Functional Materials |language=en |volume=18 |issue=19 |pages=2855–2861 |doi=10.1002/adfm.200701261}}</ref>
 
PVA is commonly used in household sponges that absorb more water than [[Polyurethane]] sponges. PVA glue is commonly used for glueing porous materials like wood, paper and cloth.