Sorafenib: Difference between revisions

Content deleted Content added
Adverse effects: +grapefruit interaction
Tag: Reverted
Undid revision 1129537790 by Neo139 (talk) wrong audience; WP:MEDMOS; WP:NOTGUIDE
Line 121:
 
The phase III DECISION trial showed significant improvement in progression-free survival but not in overall survival. However, as is known, the side effects were very frequent, specially hand and foot skin reaction.<ref>{{cite web|url=https://www.medpagetoday.com/meetingcoverage/asco/39545|title=ASCO: Sorafenib Halts Resistant Thyroid Cancer|date=4 June 2013|website=www.medpagetoday.com|access-date=21 December 2018|archive-date=23 March 2021|archive-url=https://web.archive.org/web/20210323215502/https://www.medpagetoday.com/MeetingCoverage/ASCO/39545|url-status=live}}</ref>
 
==Interactions==
Consumption of [[grapefruit]] while on sorafenib must be avoided as it can cause [[myelotoxicity]].<ref>{{cite web |title=Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? | url=https://www.cmaj.ca/content/suppl/2012/11/26/cmaj.120951.DC1/grape-bailey-1-at.pdf | access-date=2022-12-25 | date=2013-03-05 | first1=David G. |last1=Bailey |first2=George |last2=Dresser |first3=J. Malcolm O. |last3=Arnold}}</ref>
 
==Adverse effects==