4-Hexylresorcinol: Difference between revisions

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{{Short description|Chemical compound}}
{{cs1 config |name-list-style=vanc |display-authors=6}}
{{Drugbox
| verifiedrevid = 443857623
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<!--Clinical data-->
| tradename = S.T.37, Crystoids<ref>{{cite web |title=Hexylresorcinol |url=https://webbook.nist.gov/cgi/cbook.cgi?ID=136-77-6 |website=NIST Chemistry WebBook, SRD 69 |publisher=NIST |access-date=19 April 2024}}</ref>
| tradename = S.T.37, Crystoids
| Drugs.com = {{drugs.com|international|hexylresorcinol}}
| pregnancy_category =
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As an [[antiseptic]], it is marketed as '''S.T.37''' by Numark Laboratories, Inc. (in a 0.1% solution) for oral pain relief and as a topical antiseptic. It is available for use topically on small [[skin infection]]s or as an ingredient in [[throat lozenge]]s.
 
As an [[anthelmintic]], 4-hexylresorcinol was sold under the brand Crystoids.<ref>{{cncite web |title=Anthelmintic Crystoids |url=https://americanhistory.si.edu/collections/nmah_212530 |publisher=National Museum of American History |access-date=December19 April 2024 | id = ID number 1985.0481.142 |format=Object in 2022collection}}</ref>
Sytheon Ltd., USA markets 4-hexylresorcinol (trade named Synovea HR).
 
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In mice with cancer, 4-hexylresorcinol inhibited [[NF-κB]] and extended their survival rate.<ref>{{cite journal | vauthors = Kim SG, Lee SW, Park YW, Jeong JH, Choi JY | title = 4-hexylresorcinol inhibits NF-κB phosphorylation and has a synergistic effect with cisplatin in KB cells | journal = Oncology Reports | volume = 26 | issue = 6 | pages = 1527–32 | date = December 2011 | pmid = 21874263 | doi = 10.3892/or.2011.1436 | doi-access = free }}</ref>
 
4-Hexylresorcinol can be used in the synthesis of [[tetrahydrocannabihexol]]<ref>{{cite journal | doi = 10.1021/ja01255a061 | title = Tetrahydrocannabinol Homologs and Analogs with Marihuana Activity. XIII<sup>1</sup> | date = 1942 | last1vauthors = Adams | first1 = Roger | last2 =R, Loewe | first2 = S. | last3 =, Smith | first3 = C. M. | last4 =CM, McPhee | first4 = W. D.WD | journal = Journal of the American Chemical Society | volume = 64 | issue = 3 | pages = 694–697 }}</ref>
 
== References ==
{{Reflist}}
<references />
 
{{Throat preparations}}