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'''''Aspergillus sclerotiorum''''' is a [[species]] of fungus in the [[genus]] ''[[Aspergillus]]''. It is from the ''Circumdati'' section.<ref>{{cite journal | last1 = Siqueira | first1 = JPZ | last2 = Sutton | first2 = DA | last3 = Gené | first3 = J | last4 = García | first4 = D | last5 = Wiederhold | first5 = N | last6 = Peterson | first6 = SW | last7 = Guarro | first7 = J | year = 2017 | title = Multilocus phylogeny and antifungal susceptibility of Aspergillus section Circumdati from clinical samples and description of A. pseudosclerotiorum sp. nov | journal = J Clin Microbiol | volume = 55 | issue = 3 | pages = 947–958 | doi = 10.1128/JCM.02012-16 | pmid = 28053212 | pmc = 5328464 | doi-access = free }}</ref> The species was first described in 1933.<ref name="thomchurch1926">{{cite journal | last1 = Huber | first1 = G.A. | year = 1933 | title = Aspergillus sclerotiorum, n. sp., and its relation to decay of apples | journal = Phytopathology | volume = 23 | pages = 306–308 }}</ref> ''A. sclerotiorum'' has been reported to produce penicillic acid, xanthomegnin, viomellein, and vioxanthin.<ref name="isolation">{{cite journal|
In 2016, the [[genome]] of ''A. sclerotiorum'' was [[Sequencing|sequenced]] as a part of the ''Aspergillus'' whole-genome sequencing project - a project dedicated to performing whole-genome sequencing of all members of the genus ''Aspergillus''.<ref name="jgi">{{cite web|url=https://genome.jgi.doe.gov/Aspsc1/Aspsc1.home.html|title=Aspergillus sclerotiorum CBS 549.65 v1.0|website=Department of Energy Joint Genome Institute}}</ref> The genome assembly size was 37.97 [[base pair|Mbp]].<ref name="jgi"/>
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In a study published in Dec 2020, cadmium, chromium, and lead tolerant microbes have been isolated from contaminated mining soil and characterized. Six soil samples were collected from Nanjing mine (32°09′19.29″ N 118°56′57.04″ E). Soil samples were taken from the depth of 0~30 cm and processed within 8 h. After the collection of soil samples, these were kept on dry ice and further used to isolate fungi. Aspergillus Sclerotiorum was one of 5 identified strains that exhibited tolerance to all 3 of these heavy metals.
Molecular characterization of isolated fungi was performed and amplified sequences were deposited in the GenBank NCBI database. Metal tolerance of the various strains has been determined by measuring the minimum inhibitory concentrations (MICs) and the tolerance indexes of all the tested strains against Cd, Cr, and Pb. Bioaccumulation capacities of Trichoderma harzianum and Komagataella phaffi have also been assessed. These findings helped us find a novel strain of Komagataella phaffi and suggested it to be the potential mycoremediation microbe to alleviate the contamination of Cd, Cr, and Pb. Future studies of this fungal strain can help us to understand its resistance mechanism against other heavy metals, too.<ref>{{cite journal |last1=Liaquat |first1=Fiza |last2=Munis |first2=Muhammad Farooq Hussain |last3=Haroon |first3=Urooj |last4=Arif |first4=Samiah |last5=Saqib |first5=Saddam |last6=Zaman |first6=Wajid |last7=Khan |first7=Ali Raza |last8=Shi |first8=Jianxin |last9=Che |first9=Shengquan |last10=Liu |first10=Qunlu |title=Evaluation of Metal Tolerance of Fungal Strains Isolated from Contaminated Mining Soil of Nanjing, China |journal=Biology |date=15 December 2020 |volume=9 |issue=12 |pages=469 |doi=10.3390/biology9120469 |pmid=33333787 |pmc=7765179 |doi-access=free }}</ref>
== References ==
{{Reflist}}
{{Creative Commons text attribution notice|cc=by4|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765179/|author(s)=Laiquat, Munis, Haroon, et al}}
{{Taxonbar|from=Q6719593}}
[[Category:Aspergillus|sclerotiorum]]
[[Category:Fungi described in 1933]]
[[Category:Fungus species]]
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