A growing proportion of Science, Technology, Engineering & Mathematics (STEM) research is increasingly dependent on Cyberinfrastructure (CI). CI has experienced rapid progress in enabling technologies -- hardware, storage, networking, middleware, tools, ...

In this paper we lay out the computational challenges involved in effectively simulating complex phenomena such as sequestering CO₂ in oil and gas reservoirs. The challenges arise at multiple levels: (i) the computational complexity of simulating the ...

Solving large non-negatively constrained least squares systems is frequently used in the physical sciences to estimate model parameters which best fit experimental data. Analytical Ultracentrifugation (AUC) is an important hydrodynamic experimental ...

The Uintah Software system was developed to provide an environment for solving a fluid-structure interaction problems on structured adaptive grids on large-scale, long-running, data-intensive problems. Uintah uses a novel asynchronous task-based ...